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1 |
Material Type: Artigo
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Genetic Regulation of Birth Weight and Fasting Glucose by a Common Polymorphism in the Islet Cell Promoter of the Glucokinase GeneWEEDON, Michael N ; FRAYLING, Timothy M ; SMITH, George Davey ; RING, Sue ; JONES, Richard ; GOLDING, Jean ; BYBERG, Liisa ; MANN, Vera ; AXELSSON, Tomas ; SYVÄNEN, Ann-Christine ; LEON, David ; HATTERSLEY, Andrew T ; SHIELDS, Beverley ; KNIGHT, Beatrice ; TURNER, Tina ; METCALF, Bradley S ; VOSS, Linda ; WILKIN, Terence J ; MCCARTHY, Anne ; BEN-SHLOMO, YoavDiabetes (New York, N.Y.), 2005-02, Vol.54 (2), p.576-581 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-CellsCardozo, Alessandra K ; Ortis, Fernanda ; Storling, Joachim ; Feng, Ying-Mei ; Rasschaert, Joanne ; Tonnesen, Morten ; Van Eylen, Françoise ; Mandrup-Poulsen, Thomas ; Herchuelz, André ; Eizirik, Décio LDiabetes (New York, N.Y.), 2005-02, Vol.54 (2), p.452-461 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Microbial phenolic metabolites improve glucose-stimulated insulin secretion and protect pancreatic beta cells against tert-butyl hydroperoxide-induced toxicity via ERKs and PKC pathwaysFernández-Millán, Elisa ; Ramos, Sonia ; Alvarez, Carmen ; Bravo, Laura ; Goya, Luis ; Martín, María ÁngelesFood and chemical toxicology, 2014-04, Vol.66, p.245-253 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Functional and Molecular Defects of Pancreatic Islets in Human Type 2 DiabetesDEL GUERRA, Silvia ; LUPI, Roberto ; DEL PRATO, Stefano ; MARCHETTI, Piero ; MARSELLI, Lorella ; MASINI, Matilde ; BUGLIANI, Marco ; SBRANA, Simone ; TORRI, Scilla ; POLLERA, Maria ; BOGGI, Ugo ; MOSCA, FrancoDiabetes (New York, N.Y.), 2005-03, Vol.54 (3), p.727-735 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Vildagliptin, a Dipeptidyl Peptidase-IV Inhibitor, Improves Model-Assessed β-Cell Function in Patients with Type 2 DiabetesMari, A ; Sallas, W. M ; He, Y. L ; Watson, C ; Ligueros-Saylan, M ; Dunning, B. E ; Deacon, C. F ; Holst, J. J ; Foley, J. EThe journal of clinical endocrinology and metabolism, 2005-08, Vol.90 (8), p.4888-4894 [Periódico revisado por pares]Bethesda, MD: Endocrine SocietyTexto completo disponível |
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Material Type: Artigo
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The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathwaysFavaro, E. ; Granata, R. ; Miceli, I. ; Baragli, A. ; Settanni, F. ; Cavallo Perin, P. ; Ghigo, E. ; Camussi, G. ; Zanone, M. M.Diabetologia, 2012-04, Vol.55 (4), p.1058-1070 [Periódico revisado por pares]Berlin/Heidelberg: Springer-VerlagTexto completo disponível |
7 |
Material Type: Artigo
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L-cysteine inhibits insulin release from the pancreatic β-cell : Possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitterKANEKO, Yukiko ; KIMURA, Yuka ; KIMURA, Hideo ; NIKI, IchiroDiabetes (New York, N.Y.), 2006-05, Vol.55 (5), p.1391-1397 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
8 |
Material Type: Artigo
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Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell lineMorgan, D ; Oliveira-Emilio, H. R ; Keane, D ; Hirata, A. E ; Santos da Rocha, M ; Bordin, S ; Curi, R ; Newsholme, P ; Carpinelli, A. RDiabetologia, 2007-02, Vol.50 (2), p.359-369 [Periódico revisado por pares]Berlin: Berlin/Heidelberg : Springer-VerlagTexto completo disponível |
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Material Type: Artigo
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Exendin-4 Suppresses Src Activation and Reactive Oxygen Species Production in Diabetic Goto-Kakizaki Rat Islets in an Epac-Dependent MannerMUKAI, Eri ; FUJIMOTO, Shimpei ; SATO, Hiroki ; ONEYAMA, Chitose ; KOMINATO, Rieko ; SATO, Yuichi ; SASAKI, Mayumi ; NISHI, Yuichi ; OKADA, Masato ; INAGAKI, NobuyaDiabetes (New York, N.Y.), 2011-01, Vol.60 (1), p.218-226 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
10 |
Material Type: Artigo
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Co-immobilization of urokinase and thrombomodulin on islet surfaces by poly(ethylene glycol)-conjugated phospholipidChen, Hao ; Teramura, Yuji ; Iwata, HirooJournal of controlled release, 2011-03, Vol.150 (2), p.229-234 [Periódico revisado por pares]Kidlington: Elsevier B.VTexto completo disponível |