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Material Type: Artigo
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Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosusHasni, Sarfaraz A ; Gupta, Sarthak ; Davis, Michael ; Poncio, Elaine ; Temesgen-Oyelakin, Yenealem ; Carlucci, Philip M ; Wang, Xinghao ; Naqi, Mohammad ; Playford, Martin P ; Goel, Rishi R ; Li, Xiaobai ; Biehl, Ann J ; Ochoa-Navas, Isabel ; Manna, Zerai ; Shi, Yinghui ; Thomas, Donald ; Chen, Jinguo ; Biancotto, Angélique ; Apps, Richard ; Cheung, Foo ; Kotliarov, Yuri ; Babyak, Ashley L ; Zhou, Huizhi ; Shi, Rongye ; Stagliano, Katie ; Tsai, Wanxia Li ; Vian, Laura ; Gazaniga, Nathalia ; Giudice, Valentina ; Lu, Shajia ; Brooks, Stephen R ; MacKay, Meggan ; Gregersen, Peter ; Mehta, Nehal N ; Remaley, Alan T ; Diamond, Betty ; O'Shea, John J ; Gadina, Massimo ; Kaplan, Mariana JNature communications, 2021-06, Vol.12 (1), p.3391-11, Article 3391 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosusFurie, Richard ; Werth, Victoria P ; Merola, Joseph F ; Stevenson, Lauren ; Reynolds, Taylor L ; Naik, Himanshu ; Wang, Wenting ; Christmann, Romy ; Gardet, Agnes ; Pellerin, Alex ; Hamann, Stefan ; Auluck, Pavan ; Barbey, Catherine ; Gulati, Parul ; Rabah, Dania ; Franchimont, NathalieThe Journal of clinical investigation, 2019-03, Vol.129 (3), p.1359-1371 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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3 |
Material Type: Artigo
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B cell-intrinsic TLR9 expression is protective in murine lupusTilstra, Jeremy S ; John, Shinu ; Gordon, Rachael A ; Leibler, Claire ; Kashgarian, Michael ; Bastacky, Sheldon ; Nickerson, Kevin M ; Shlomchik, Mark JThe Journal of clinical investigation, 2020-06, Vol.130 (6), p.3172-3187 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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4 |
Material Type: Artigo
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Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestationsJeremiah, Nadia ; Neven, Bénédicte ; Gentili, Matteo ; Callebaut, Isabelle ; Maschalidi, Sophia ; Stolzenberg, Marie-Claude ; Goudin, Nicolas ; Frémond, Marie-Louis ; Nitschke, Patrick ; Molina, Thierry J ; Blanche, Stéphane ; Picard, Capucine ; Rice, Gillian I ; Crow, Yanick J ; Manel, Nicolas ; Fischer, Alain ; Bader-Meunier, Brigitte ; Rieux-Laucat, FrédéricThe Journal of clinical investigation, 2014-12, Vol.124 (12), p.5516-5520 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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Material Type: Artigo
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Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groupsWang, Yong-Fei ; Zhang, Yan ; Lin, Zhiming ; Zhang, Huoru ; Wang, Ting-You ; Cao, Yujie ; Morris, David L ; Sheng, Yujun ; Yin, Xianyong ; Zhong, Shi-Long ; Gu, Xiaoqiong ; Lei, Yao ; He, Jing ; Wu, Qi ; Shen, Jiangshan Jane ; Yang, Jing ; Lam, Tai-Hing ; Lin, Jia-Huang ; Mai, Zhi-Ming ; Guo, Mengbiao ; Tang, Yuanjia ; Chen, Yanhui ; Song, Qin ; Ban, Bo ; Mok, Chi Chiu ; Cui, Yong ; Lu, Liangjing ; Shen, Nan ; Sham, Pak C ; Lau, Chak Sing ; Smith, David K ; Vyse, Timothy J ; Zhang, Xuejun ; Lau, Yu Lung ; Yang, WanlingNature communications, 2021-02, Vol.12 (1), p.772-772, Article 772 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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6 |
Material Type: Artigo
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Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus ModelTumurkhuu, Gantsetseg ; Chen, Shuang ; Montano, Erica N ; Ercan Laguna, Duygu ; De Los Santos, Gabriela ; Yu, Jeong Min ; Lane, Malcolm ; Yamashita, Michifumi ; Markman, Janet L ; Blanco, Luz P ; Kaplan, Mariana J ; Shimada, Kenichi ; Crother, Timothy R ; Ishimori, Mariko ; Wallace, Daniel J ; Jefferies, Caroline A ; Arditi, MosheFrontiers in immunology, 2020-09, Vol.11, p.554725 [Periódico revisado por pares]Switzerland: Frontiers Research FoundationTexto completo disponível |
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7 |
Material Type: Artigo
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T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunityMoulton, Vaishali R ; Tsokos, George CThe Journal of clinical investigation, 2015-06, Vol.125 (6), p.2220-2227 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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8 |
Material Type: Artigo
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High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosusOke, Vilija ; Gunnarsson, Iva ; Dorschner, Jessica ; Eketjäll, Susanna ; Zickert, Agneta ; Niewold, Timothy B ; Svenungsson, ElisabetArthritis research & therapy, 2019-04, Vol.21 (1), p.107-107, Article 107 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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9 |
Material Type: Artigo
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Roles of circular RNAs in immune regulation and autoimmune diseasesZhou, Zheng ; Sun, Bao ; Huang, Shiqiong ; Zhao, LinglingCell death & disease, 2019-06, Vol.10 (7), p.503-13, Article 503 [Periódico revisado por pares]England: Springer Nature B.VTexto completo disponível |
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10 |
Material Type: Artigo
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Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populationsAbsher, Devin M ; Li, Xinrui ; Waite, Lindsay L ; Gibson, Andrew ; Roberts, Kevin ; Edberg, Jeffrey ; Chatham, W Winn ; Kimberly, Robert P O'Shea, JohnPLoS genetics, 2013-08, Vol.9 (8), p.e1003678-e1003678 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |