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Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors
Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors
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Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors

Cui, Shengyang ; Wang, Yongjin ; Wang, Yuting ; Tang, Xia ; Ren, Xiaomei ; Zhang, Lei ; Xu, Yong ; Zhang, Zhang ; Zhang, Zhi-Min ; Lu, Xiaoyun ; Ding, Ke

European journal of medicinal chemistry, 2019-10, Vol.179, p.470-482 [Periódico revisado por pares]

France: Elsevier Masson SAS

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2
Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors
Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors
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Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors

Qin, Qiaohua ; Fu, Qinglin ; Wang, Xin ; Lv, Ruicheng ; Lu, Shuyu ; Guo, Zhiqiang ; Wu, Tianxiao ; Sun, Yin ; Sun, Yixiang ; Liu, Nian ; Zhao, Dongmei ; Cheng, Maosheng

European journal of medicinal chemistry, 2023-05, Vol.253, p.115291-115291, Article 115291 [Periódico revisado por pares]

France: Elsevier Masson SAS

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3
Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors
Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors
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Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors

Duan, Yunxin ; Wang, Jie ; Zhu, Sihua ; Tu, Zheng-Chao ; Zhang, Zhang ; Chan, Shingpan ; Ding, Ke

European journal of medicinal chemistry, 2020-10, Vol.203, p.112552, Article 112552 [Periódico revisado por pares]

France: Elsevier Masson SAS

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4
Discovery of 3-pyrazolyl-substituted pyrazolo[1,5-a]pyrimidine derivatives as potent TRK inhibitors to overcome clinically acquired resistance
Discovery of 3-pyrazolyl-substituted pyrazolo[1,5-a]pyrimidine derivatives as potent TRK inhibitors to overcome clinically acquired resistance
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Discovery of 3-pyrazolyl-substituted pyrazolo[1,5-a]pyrimidine derivatives as potent TRK inhibitors to overcome clinically acquired resistance

Gong, Yi ; Wu, Feng-Xu ; Wang, Ming-Shu ; Xu, Hong-Chuang ; Zhuo, Lin-Sheng ; Yang, Guang-Fu ; Huang, Wei

European journal of medicinal chemistry, 2022-11, Vol.241, p.114654-114654, Article 114654 [Periódico revisado por pares]

Elsevier Masson SAS

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5
Identification and structural analysis of a selective tropomyosin receptor kinase C (TRKC) inhibitor
Identification and structural analysis of a selective tropomyosin receptor kinase C (TRKC) inhibitor
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Identification and structural analysis of a selective tropomyosin receptor kinase C (TRKC) inhibitor

Wang, Zhijie ; Ren, Jiwei ; Jia, Kun ; Zhao, Yuming ; Liang, Li ; Cheng, Zitian ; Huang, Fei ; Zhao, Xiaofei ; Cheng, Jie ; Song, Shiyu ; Sheng, Tiancheng ; Wan, Weiqi ; Shu, Qingqing ; Wu, Donglin ; Zhang, Junhao ; Lu, Tao ; Chen, Yadong ; Ran, Ting ; Lu, Shuai

European journal of medicinal chemistry, 2022-11, Vol.241, p.114601-114601, Article 114601 [Periódico revisado por pares]

Elsevier Masson SAS

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