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Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus
Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus
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Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus

Lam, Angela M ; Espiritu, Christine ; Vogel, Robert ; Ren, Suping ; Lau, Vincent ; Kelly, Mollie ; Kuduk, Scott D ; Hartman, George D ; Flores, Osvaldo A ; Klumpp, Klaus

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1) [Periódico revisado por pares]

United States: American Society for Microbiology

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2
Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
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Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study

Gounder, Mrinal ; Schöffski, Patrick ; Jones, Robin L ; Agulnik, Mark ; Cote, Gregory M ; Villalobos, Victor M ; Attia, Steven ; Chugh, Rashmi ; Chen, Tom Wei-Wu ; Jahan, Thierry ; Loggers, Elizabeth T ; Gupta, Abha ; Italiano, Antoine ; Demetri, George D ; Ratan, Ravin ; Davis, Lara E ; Mir, Olivier ; Dileo, Palma ; Van Tine, Brian A ; Pressey, Joseph G ; Lingaraj, Trupti ; Rajarethinam, Anand ; Sierra, Laura ; Agarwal, Shefali ; Stacchiotti, Silvia

The lancet oncology, 2020-11, Vol.21 (11), p.1423-1432 [Periódico revisado por pares]

England: Elsevier Ltd

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3
A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers
A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers
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A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Paik, Paul K ; Shen, Ronglai ; Berger, Michael F ; Ferry, David ; Soria, Jean-Charles ; Mathewson, Alastair ; Rooney, Claire ; Smith, Neil R ; Cullberg, Marie ; Kilgour, Elaine ; Landers, Donal ; Frewer, Paul ; Brooks, Nigel ; André, Fabrice

Clinical cancer research, 2017-09, Vol.23 (18), p.5366-5373 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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4
Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study
Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study
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Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study

Italiano, Antoine ; Soria, Jean-Charles ; Toulmonde, Maud ; Michot, Jean-Marie ; Lucchesi, Carlo ; Varga, Andrea ; Coindre, Jean-Michel ; Blakemore, Stephen J ; Clawson, Alicia ; Suttle, Benjamin ; McDonald, Alice A ; Woodruff, Mark ; Ribich, Scott ; Hedrick, Eric ; Keilhack, Heike ; Thomson, Blythe ; Owa, Takashi ; Copeland, Robert A ; Ho, Peter T C ; Ribrag, Vincent

The lancet oncology, 2018-05, Vol.19 (5), p.649-659 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Oral Tecovirimat for the Treatment of Smallpox
Oral Tecovirimat for the Treatment of Smallpox
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Oral Tecovirimat for the Treatment of Smallpox

Grosenbach, Douglas W ; Honeychurch, Kady ; Rose, Eric A ; Chinsangaram, Jarasvech ; Frimm, Annie ; Maiti, Biswajit ; Lovejoy, Candace ; Meara, Ingrid ; Long, Paul ; Hruby, Dennis E

The New England journal of medicine, 2018-07, Vol.379 (1), p.44-53 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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6
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
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Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

Byrd, John C ; Harrington, Bonnie ; O’Brien, Susan ; Jones, Jeffrey A ; Schuh, Anna ; Devereux, Steve ; Chaves, Jorge ; Wierda, William G ; Awan, Farrukh T ; Brown, Jennifer R ; Hillmen, Peter ; Stephens, Deborah M ; Ghia, Paolo ; Barrientos, Jacqueline C ; Pagel, John M ; Woyach, Jennifer ; Johnson, Dave ; Huang, Jane ; Wang, Xiaolin ; Kaptein, Allard ; Lannutti, Brian J ; Covey, Todd ; Fardis, Maria ; McGreivy, Jesse ; Hamdy, Ahmed ; Rothbaum, Wayne ; Izumi, Raquel ; Diacovo, Thomas G ; Johnson, Amy J ; Furman, Richard R

The New England journal of medicine, 2016-01, Vol.374 (4), p.323-332 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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7
A Novel G Protein-Biased Agonist at the δ Opioid Receptor with Analgesic Efficacy in Models of Chronic Pain
A Novel G Protein-Biased Agonist at the δ Opioid Receptor with Analgesic Efficacy in Models of Chronic Pain
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A Novel G Protein-Biased Agonist at the δ Opioid Receptor with Analgesic Efficacy in Models of Chronic Pain

Conibear, Alexandra E ; Asghar, Junaid ; Hill, Rob ; Henderson, Graeme ; Borbely, Eva ; Tekus, Valeria ; Helyes, Zsuzsanna ; Palandri, Josephine ; Bailey, Chris ; Starke, Ingemar ; von Mentzer, Bengt ; Kendall, David ; Kelly, Eamonn

The Journal of pharmacology and experimental therapeutics, 2020-02, Vol.372 (2), p.224-236 [Periódico revisado por pares]

United States: The American Society for Pharmacology and Experimental Therapeutics

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8
Selective targeting of tumor cells and tumor associated macrophages separately by twin-like core-shell nanoparticles for enhanced tumor-localized chemoimmunotherapy
Selective targeting of tumor cells and tumor associated macrophages separately by twin-like core-shell nanoparticles for enhanced tumor-localized chemoimmunotherapy
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Selective targeting of tumor cells and tumor associated macrophages separately by twin-like core-shell nanoparticles for enhanced tumor-localized chemoimmunotherapy

Wang, Tianqi ; Zhang, Jing ; Hou, Teng ; Yin, Xiaolan ; Zhang, Na

Nanoscale, 2019-08, Vol.11 (29), p.13934-13946 [Periódico revisado por pares]

England: Royal Society of Chemistry

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9
Fusarithioamide B, a new benzamide derivative from the endophytic fungus Fusarium chlamydosporium with potent cytotoxic and antimicrobial activities
Fusarithioamide B, a new benzamide derivative from the endophytic fungus Fusarium chlamydosporium with potent cytotoxic and antimicrobial activities
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Fusarithioamide B, a new benzamide derivative from the endophytic fungus Fusarium chlamydosporium with potent cytotoxic and antimicrobial activities

Ibrahim, Sabrin R.M. ; Mohamed, Gamal A. ; Al Haidari, Rwaida A. ; Zayed, Mohamed F. ; El-Kholy, Amal A. ; Elkhayat, Ehab S. ; Ross, Samir A.

Bioorganic & medicinal chemistry, 2018-02, Vol.26 (3), p.786-790 [Periódico revisado por pares]

England: Elsevier Ltd

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10
1,2,4-Oxadiazole-Based Bio-Isosteres of Benzamides: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo
1,2,4-Oxadiazole-Based Bio-Isosteres of Benzamides: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo
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1,2,4-Oxadiazole-Based Bio-Isosteres of Benzamides: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo

Yang, Sen ; Ren, Chao-Li ; Ma, Tian-Yang ; Zou, Wen-Qian ; Dai, Li ; Tian, Xiao-Yu ; Liu, Xing-Hai ; Tan, Cheng-Xia

International journal of molecular sciences, 2021-02, Vol.22 (5), p.2367 [Periódico revisado por pares]

Switzerland: MDPI AG

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