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11
Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity
Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity
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Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity

Schönegge, Anne-Marie ; Gallion, Jonathan ; Picard, Louis-Philippe ; Wilkins, Angela D. ; Le Gouill, Christian ; Audet, Martin ; Stallaert, Wayne ; Lohse, Martin J. ; Kimmel, Marek ; Lichtarge, Olivier ; Bouvier, Michel

Nature communications, 2017-12, Vol.8 (1), p.1-12, Article 2169 [Periódico revisado por pares]

London: Nature Publishing Group

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12
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
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GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics

Wright, Shane C ; Motso, Aikaterini ; Koutsilieri, Stefania ; Beusch, Christian M ; Sabatier, Pierre ; Berghella, Alessandro ; Blondel-Tepaz, Élodie ; Mangenot, Kimberley ; Pittarokoilis, Ioannis ; Sismanoglou, Despoina-Christina ; Le Gouill, Christian ; Olsen, Jesper V ; Zubarev, Roman A ; Lambert, Nevin A ; Hauser, Alexander S ; Bouvier, Michel ; Lauschke, Volker M

Nature communications, 2023-10, Vol.14 (1), p.6243-6243, Article 6243 [Periódico revisado por pares]

England: Nature Publishing Group

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13
Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
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Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

Hamoud, Noumeira ; Tran, Viviane ; Aimi, Takahiro ; Kakegawa, Wataru ; Lahaie, Sylvie ; Thibault, Marie-Pier ; Pelletier, Ariane ; Wong, G William ; Kim, In-San ; Kania, Artur ; Yuzaki, Michisuke ; Bouvier, Michel ; Côté, Jean-François

Nature communications, 2018-10, Vol.9 (1), p.4470-16, Article 4470 [Periódico revisado por pares]

England: Nature Publishing Group

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14
Computationally designed GPCR quaternary structures bias signaling pathway activation
Computationally designed GPCR quaternary structures bias signaling pathway activation
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Computationally designed GPCR quaternary structures bias signaling pathway activation

Paradis, Justine S ; Feng, Xiang ; Murat, Brigitte ; Jefferson, Robert E ; Sokrat, Badr ; Szpakowska, Martyna ; Hogue, Mireille ; Bergkamp, Nick D ; Heydenreich, Franziska M ; Smit, Martine J ; Chevigné, Andy ; Bouvier, Michel ; Barth, Patrick

Nature communications, 2022-11, Vol.13 (1), p.6826-6826, Article 6826 [Periódico revisado por pares]

England: Nature Publishing Group

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15
Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy
Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy
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Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy

Teixeira, Larissa B. ; Parreiras-e-Silva, Lucas T. ; Bruder-Nascimento, Thiago ; Duarte, Diego A. ; Simões, Sarah C. ; Costa, Rafael M. ; Rodríguez, Deisy Y. ; Ferreira, Pedro A. B. ; Silva, Carlos A. A. ; Abrao, Emiliana P. ; Oliveira, Eduardo B. ; Bouvier, Michel ; Tostes, Rita C. ; Costa-Neto, Claudio M.

Scientific reports, 2017-09, Vol.7 (1), p.1-10, Article 11903 [Periódico revisado por pares]

London: Nature Publishing Group

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16
G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
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G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

Kossatz, Elk ; Diez-Alarcia, Rebeca ; Gaitonde, Supriya A. ; Ramon-Duaso, Carla ; Stepniewski, Tomasz Maciej ; Aranda-Garcia, David ; Muneta-Arrate, Itziar ; Tepaz, Elodie ; Saen-Oon, Suwipa ; Soliva, Robert ; Shahraki, Aida ; Moreira, David ; Brea, Jose ; Loza, Maria Isabel ; de la Torre, Rafael ; Kolb, Peter ; Bouvier, Michel ; Meana, J. Javier ; Robledo, Patricia ; Selent, Jana

Nature communications, 2024-05, Vol.15 (1), p.4307-15, Article 4307 [Periódico revisado por pares]

London: Nature Publishing Group

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17
Comprehensive Analysis of Kisspeptin Signaling: Effects on Cellular Dynamics in Cervical Cancer
Comprehensive Analysis of Kisspeptin Signaling: Effects on Cellular Dynamics in Cervical Cancer
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Comprehensive Analysis of Kisspeptin Signaling: Effects on Cellular Dynamics in Cervical Cancer

Rodríguez-Sarmiento, Deisy Yurley ; Rondón-Villarreal, Paola ; Scarpelli-Pereira, Pedro Henrique ; Bouvier, Michel

Biomolecules (Basel, Switzerland), 2024-07, Vol.14 (8), p.923 [Periódico revisado por pares]

Basel: MDPI AG

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18
How carvedilol does not activate β2-adrenoceptors
How carvedilol does not activate β2-adrenoceptors
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How carvedilol does not activate β2-adrenoceptors

Lefkowitz, Robert J ; Rockman, Howard A ; Shim, Paul J ; Liu, Samuel ; Ahn, Seungkirl ; Pani, Biswaranjan ; Rajagopal, Sudarshan ; Shenoy, Sudha K ; Bouvier, Michel ; Benovic, Jeffrey L ; Liggett, Stephen B ; Ruffolo, Robert R ; Bristow, Michael R ; Packer, Milton

Nature communications, 2023-11, Vol.14 (1), p.7866-7866, Article 7866 [Periódico revisado por pares]

London: Nature Publishing Group

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19
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
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Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Sokolina, Kate ; Kittanakom, Saranya ; Snider, Jamie ; Kotlyar, Max ; Maurice, Pascal ; Gandía, Jorge ; Benleulmi‐Chaachoua, Abla ; Tadagaki, Kenjiro ; Oishi, Atsuro ; Wong, Victoria ; Malty, Ramy H ; Deineko, Viktor ; Aoki, Hiroyuki ; Amin, Shahreen ; Yao, Zhong ; Morató, Xavier ; Otasek, David ; Kobayashi, Hiroyuki ; Menendez, Javier ; Auerbach, Daniel ; Angers, Stephane ; Pržulj, Natasa ; Bouvier, Michel ; Babu, Mohan ; Ciruela, Francisco ; Jockers, Ralf ; Jurisica, Igor ; Stagljar, Igor

Molecular systems biology, 2017-03, Vol.13 (3), p.918-n/a [Periódico revisado por pares]

England: EMBO Press

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20
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response
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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Benredjem, Besma ; Gallion, Jonathan ; Pelletier, Dennis ; Dallaire, Paul ; Charbonneau, Johanie ; Cawkill, Darren ; Nagi, Karim ; Gosink, Mark ; Lukasheva, Viktoryia ; Jenkinson, Stephen ; Ren, Yong ; Somps, Christopher ; Murat, Brigitte ; Van Der Westhuizen, Emma ; Le Gouill, Christian ; Lichtarge, Olivier ; Schmidt, Anne ; Bouvier, Michel ; Pineyro, Graciela

Nature communications, 2019-09, Vol.10 (1), p.4075-4075, Article 4075 [Periódico revisado por pares]

England: Nature Publishing Group

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