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1 |
Material Type: Artigo
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Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensorsYoon Namkung Christian LeGouill; Sahil Kumar; Yubo Cao; Larissa B Teixeira; Viktoriya Lukasheva; Jenna Giubilaro; Sarah Capelupe Simões; Jean-Michel Longpré; Dominic Devost; Terence E Hébert; Graciela Piñeyro; Richard Leduc; Claudio Miguel da Costa Neto; Michel Bouvier; Stéphane A LaporteScience Signaling Washington v. 11, n. 559,art. eaat 1631, 2018Washington 2018Acesso online. A biblioteca também possui exemplares impressos. |
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Material Type: Artigo
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Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensorsNamkung, Yoon ; LeGouill, Christian ; Kumar, Sahil ; Cao, Yubo ; Teixeira, Larissa B ; Lukasheva, Viktoriya ; Giubilaro, Jenna ; Simões, Sarah C ; Longpré, Jean-Michel ; Devost, Dominic ; Hébert, Terence E ; Piñeyro, Graciela ; Leduc, Richard ; Costa-Neto, Claudio M ; Bouvier, Michel ; Laporte, Stéphane AScience signaling, 2018-12, Vol.11 (559) [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cellsYagi, Hiroshi ; Tan, Wenfu ; Dillenburg-Pilla, Patricia ; Armando, Sylvain ; Amornphimoltham, Panomwat ; Simaan, May ; Weigert, Roberto ; Molinolo, Alfredo A ; Bouvier, Michel ; Gutkind, J SilvioScience signaling, 2011-09, Vol.4 (191), p.ra60-ra60 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9Luttrell, Louis M ; Wang, Jialu ; Plouffe, Bianca ; Smith, Jeffrey S ; Yamani, Lama ; Kaur, Suneet ; Jean-Charles, Pierre-Yves ; Gauthier, Christophe ; Lee, Mi-Hye ; Pani, Biswaranjan ; Kim, Jihee ; Ahn, Seungkirl ; Rajagopal, Sudarshan ; Reiter, Eric ; Bouvier, Michel ; Shenoy, Sudha K ; Laporte, Stéphane A ; Rockman, Howard A ; Lefkowitz, Robert JScience signaling, 2018-09, Vol.11 (549) [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Conformation- and activation-based BRET sensors differentially report on GPCR–G protein couplingWright, Shane C ; Avet, Charlotte ; Gaitonde, Supriya A ; Muneta-Arrate, Itziar ; Christian Le Gouill ; Hogue, Mireille ; Breton, Billy ; Koutsilieri, Stefania ; Rebeca Diez Alarcia ; Héroux, Madeleine ; Lauschke, Volker M ; Bouvier, MichelScience signaling, 2024-06, Vol.17 (841), p.eadi4747 [Periódico revisado por pares]Washington: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogsZimmerman, Brandon ; Beautrait, Alexandre ; Aguila, Benjamin ; Charles, Ricardo ; Escher, Emanuel ; Claing, Audrey ; Bouvier, Michel ; Laporte, Stéphane AScience signaling, 2012-04, Vol.5 (221), p.ra33-ra33 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRsWright, Shane C ; Cañizal Maria Consuelo Alonso ; Benkel Tobias ; Simon, Katharina ; Le Gouill Christian ; Matricon Pierre ; Yoon, Namkung ; Lukasheva Viktoria ; König, Gabriele M ; Laporte, Stéphane A ; Carlsson Jens ; Kostenis Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, CarstenScience signaling, 2018-12, Vol.11 (559) [Periódico revisado por pares]Washington: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Type 2 diabetes–associated variants of the MT2 melatonin receptor affect distinct modes of signalingKaramitri Angeliki ; Plouffe Bianca ; Bonnefond Amélie ; Chen, Min ; Gallion, Jonathan ; Guillaume Jean-Luc ; Hegron Alan ; Boissel Mathilde ; Canouil Mickaël ; Langenberg, Claudia ; Wareham, Nicholas J ; Le Gouill Christian ; Lukasheva Viktoria ; Lichtarge Olivier ; Froguel Philippe ; Bouvier, Michel ; Jockers RalfScience signaling, 2018-08, Vol.11 (545) [Periódico revisado por pares]Washington: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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FZD(5) is a G alpha(q)-coupled receptor that exhibits the functional hallmarks of prototypical GPCRsWright, Shane C. ; Canizal, Maria Consuelo Alonso ; Benkel, Tobias ; Simon, Katharina ; Le Gouill, Christian ; Matricon, Pierre ; Namkung, Yoon ; Lukasheva, Viktoria ; Koenig, Gabriele M. ; Laporte, Stephane A. ; Carlsson, Jens ; Kostenis, Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, CarstenScience signaling, 2018, Vol.11 (559) [Periódico revisado por pares]Texto completo disponível |
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Material Type: Artigo
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FZD 5 is a Gα q -coupled receptor that exhibits the functional hallmarks of prototypical GPCRsWright, Shane C ; Cañizal, Maria Consuelo Alonso ; Benkel, Tobias ; Simon, Katharina ; Le Gouill, Christian ; Matricon, Pierre ; Namkung, Yoon ; Lukasheva, Viktoria ; König, Gabriele M ; Laporte, Stéphane A ; Carlsson, Jens ; Kostenis, Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, CarstenScience signaling, 2018-12, Vol.11 (559) [Periódico revisado por pares]United StatesTexto completo disponível |