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Molecular basis for amyloid-β polymorphism
Molecular basis for amyloid-β polymorphism
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Molecular basis for amyloid-β polymorphism

Colletier, Jacques-Philippe ; Laganowsky, Arthur ; Landau, Meytal ; Zhao, Minglei ; Soriaga, Angela B ; Goldschmidt, Lukasz ; Flot, David ; Cascio, Duilio ; Sawaya, Michael R ; Eisenberg, David

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.16938-16943 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Expanding metabolism for biosynthesis of nonnatural alcohols
Expanding metabolism for biosynthesis of nonnatural alcohols
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Expanding metabolism for biosynthesis of nonnatural alcohols

Zhang, Kechun ; Sawaya, Michael R ; Eisenberg, David S ; Liao, James C

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20653-20658 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
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The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

Boyer, David R. ; Li, Binsen ; Sun, Chuanqi ; Fan, Weijia ; Zhou, Kang ; Hughes, Michael P. ; Sawaya, Michael R. ; Jiang, Lin ; Eisenberg, David S.

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (7), p.3592-3602 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE Protein Complex from Mycobacterium tuberculosis
Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE Protein Complex from Mycobacterium tuberculosis
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Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE Protein Complex from Mycobacterium tuberculosis

Strong, Michael ; Sawaya, Michael R. ; Wang, Shuishu ; Phillips, Martin ; Cascio, Duilio ; Eisenberg, David

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (21), p.8060-8065 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Molecular basis for insulin fibril assembly
Molecular basis for insulin fibril assembly
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Molecular basis for insulin fibril assembly

Ivanova, Magdalena I ; Sievers, Stuart A ; Sawaya, Michael R ; Wall, Joseph S ; Eisenberg, David

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (45), p.18990-18995 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Selective molecular transport through the protein shell of a bacterial microcompartment organelle
Selective molecular transport through the protein shell of a bacterial microcompartment organelle
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Selective molecular transport through the protein shell of a bacterial microcompartment organelle

Chowdhury, Chiranjit ; Chun, Sunny ; Pang, Allan ; Sawaya, Michael R. ; Sinha, Sharmistha ; Yeates, Todd O. ; Bobik, Thomas A.

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (10), p.2990-2995 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity
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The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

Hochberg, Georg K. A. ; Ecroyd, Heath ; Liu, Cong ; Cox, Dezerae ; Cascio, Duilio ; Sawaya, Michael R. ; Collier, Miranda P. ; Stroud, James ; Carver, John A. ; Baldwin, Andrew J. ; Robinson, Carol V. ; Eisenberg, David S. ; Benesch, Justin L. P. ; Laganowsky, Arthur

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5771-5771 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates
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Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates

Liu, Cong ; Zhao, Minglei ; Jiang, Lin ; Cheng, Pin-Nan ; Park, Jiyong ; Sawaya, Michael R. ; Pensalfini, Anna ; Gou, Dawei ; Berk, Arnold J. ; Glabe, Charles G. ; Nowick, James ; Eisenberg, David

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (51), p.20913-20918 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)
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Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)

Sangwan, Smriti ; Zhao, Anni ; Adams, Katrina L. ; Jayson, Christina K. ; Sawaya, Michael R. ; Guenther, Elizabeth L. ; Pan, Albert C. ; Ngo, Jennifer ; Moore, Destaye M. ; Soriaga, Angela B. ; Do, Thanh D. ; Goldschmidt, Lukasz ; Nelson, Rebecca ; Bowers, Michael T. ; Koehler, Carla M. ; Shaw, David E. ; Novitch, Bennett G. ; Eisenberg, David S.

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (33), p.8770-8775 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS
Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS
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Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS

Ivanova, Magdalena I. ; Sievers, Stuart A. ; Guenther, Elizabeth L. ; Johnson, Lisa M. ; Winkler, Duane D. ; Galaleldeen, Ahmad ; Sawaya, Michael R. ; Hart, John ; Eisenberg, David S.

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.197-201 [Periódico revisado por pares]

United States: National Academy of Sciences

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