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1 |
Material Type: Artigo
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Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry PerspectiveBohnert, Tonika ; Patel, Aarti ; Templeton, Ian ; Chen, Yuan ; Lu, Chuang ; Lai, George ; Leung, Louis ; Tse, Susanna ; Einolf, Heidi J ; Wang, Ying-Hong ; Sinz, Michael ; Stearns, Ralph ; Walsky, Robert ; Geng, Wanping ; Sudsakorn, Sirimas ; Moore, David ; He, Ling ; Wahlstrom, Jan ; Keirns, Jim ; Narayanan, Rangaraj ; Lang, Dieter ; Yang, XiaoqingDrug metabolism and disposition, 2016-08, Vol.44 (8), p.1399-1423 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Relationships Between Burnout and Resilience: Experiences of Physical Therapists and Occupational Therapists During the COVID-19 PandemicRoundy, Preston E ; Stearns, Zachary R ; Willis, Michael W ; Blevins, Joshua J ; Linton, Travis A ; Medlin, Thomas R ; Winger, Joseph G ; Dorfman, Caroline S ; Shelby, Rebecca APhysical therapy, 2023-05, Vol.103 (5), p.1 [Periódico revisado por pares]United States: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily membersSTEARNS, R. A ; CHAKRAVARTY, P. K ; CHEN, R ; SHUET-HING LEE CHIUDrug metabolism and disposition, 1995-02, Vol.23 (2), p.207-215 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated MetabolitesWEI TANG ; STEARNS, R. A ; STRAUSS, J. R ; KWEI, G. Y ; RUSHMORE, T. H ; CHIU, S.-H. L ; BAILLIE, T. A ; BANDIERA, S. M ; YONG ZHANG ; RAAB, C ; BRAUN, M. P ; DEAN, D. C ; JIANMEI PANG ; LEUNG, K. H ; DOSS, G. ADrug metabolism and disposition, 1999-03, Vol.27 (3), p.365-372 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humansPOON, Grace K ; QING CHEN ; BAILLIE, Thomas A ; WEI TANG ; TEFFERA, Yohannes ; NGUI, Jason S ; GRIFFIN, Patrick R ; BRAUN, Mathew P ; DOSS, George A ; FREEDEN, Christopher ; STEARNS, Ralph A ; EVANS, David CDrug metabolism and disposition, 2001-12, Vol.29 (12), p.1608-1613 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Cytochrome P450 3A4-Mediated Interaction of Diclofenac and QuinidineNgui, J S ; Tang, W ; Stearns, R A ; Shou, M ; Miller, R R ; Zhang, Y ; Lin, J H ; Baillie, T ADrug metabolism and disposition, 2000-09, Vol.28 (9), p.1043-1050 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Gadolinium induces macrophage apoptosisMizgerd, Joseph P. ; Molina, Ramon M. ; Stearns, Rebecca C. ; Brain, Joseph D. ; Warner, Angeline E.Journal of leukocyte biology, 1996-02, Vol.59 (2), p.189-195 [Periódico revisado por pares]United States: Society for Leukocyte BiologyTexto completo disponível |
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Material Type: Artigo
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On the Role of the Weather in the Deaths of R. F. Scott and His CompanionsSolomon, Susan ; Stearns, Charles R.Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13012-13016 [Periódico revisado por pares]United States: National Academy of Sciences of the United States of AmericaTexto completo disponível |
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Material Type: Artigo
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In vitro stimulation of warfarin metabolism by quinidine : Increases in the formation of 4'- and 10-hydroxywarfarinNGUI, Jason S ; QING CHEN ; MAGANG SHOU ; WANG, Regina W ; STEARNS, Ralph A ; BAILLIE, Thomas A ; WEI TANGDrug metabolism and disposition, 2001-06, Vol.29 (6), p.877-886 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urineBALANI, S. K ; ARISON, B. H ; MATHAI, L ; KAUFFMAN, L. R ; MILLER, R. R ; STEARNS, R. A ; I-WU CHEN ; LIN, J. HDrug metabolism and disposition, 1995-02, Vol.23 (2), p.266-270 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |