skip to main content
Idioma:
Primo Advanced Search
Primo Advanced Search Query Term
Primo Advanced Search Query Term
Primo Advanced Search Query Term
Primo Advanced Search prefilters
Busca Simples
Refinado por: assunto: Chemistry, Medicinal remover
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3‑Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS)
Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3‑Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS)
Material Type:
Artigo 		Adicionar ao Meu Espaço

Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3‑Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS)

Come, Jon H ; Collier, Philip N ; Henderson, James A ; Pierce, Albert C ; Davies, Robert J ; Le Tiran, Arnaud ; O’Dowd, Hardwin ; Bandarage, Upul K ; Cao, Jingrong ; Deininger, David ; Grey, Ron ; Krueger, Elaine B ; Lowe, Derek B ; Liang, Jianglin ; Liao, Yusheng ; Messersmith, David ; Nanthakumar, Suganthi ; Sizensky, Emmanuelle ; Wang, Jian ; Xu, Jinwang ; Chin, Elaine Y ; Damagnez, Veronique ; Doran, John D ; Dworakowski, Wojciech ; Griffith, James P ; Jacobs, Marc D ; Khare-Pandit, Suvarna ; Mahajan, Sudipta ; Moody, Cameron S ; Aronov, Alex M

Journal of medicinal chemistry, 2018-06, Vol.61 (12), p.5245-5256 [Periódico revisado por pares]

United States: American Chemical Society

Texto completo disponível

Citações Citado por
2
Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency
Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency
Material Type:
Artigo 		Adicionar ao Meu Espaço

Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency

Henderson, James A. ; Bilimoria, Darius ; Bubenik, Monica ; Cadilhac, Caroline ; Cottrell, Kevin M. ; Dietrich, Evelyne ; Denis, Francois ; Ewing, Nigel ; Falardeau, Guy ; Giroux, Simon ; Grey, Ronald ; L’Heureux, Lucille ; Liu, Bingcan ; Mani, Nagraj ; Morris, Mark ; Nicolas, Olivier ; Pereira, Oswy Z. ; Poisson, Carl ; Govinda Rao, B. ; Reddy, T. Jagadeeswar ; Selliah, Subajini ; Shawgo, Rebecca S. ; Vaillancourt, Louis ; Wang, Jian ; Yannopoulos, Constantin G. ; Chauret, Nathalie ; Berlioz-Seux, Francoise ; Chan, Laval C. ; Das, Sanjoy K. ; Grillot, Anne-Laure ; Bennani, Youssef L. ; Maxwell, John P.

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (4), p.944-947 [Periódico revisado por pares]

England: Elsevier Ltd

Texto completo disponível

Citações Citado por
3
Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: Non-symmetric inhibitors with potent activity against genotype 1a and 1b
Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: Non-symmetric inhibitors with potent activity against genotype 1a and 1b
Material Type:
Artigo 		Adicionar ao Meu Espaço

Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: Non-symmetric inhibitors with potent activity against genotype 1a and 1b

Giroux, Simon ; Bilimoria, Darius ; Cadilhac, Caroline ; Cottrell, Kevin M. ; Denis, Francois ; Dietrich, Evelyne ; Ewing, Nigel ; Henderson, James A. ; L’Heureux, Lucille ; Mani, Nagraj ; Morris, Mark ; Nicolas, Olivier ; Reddy, T. Jagadeeswar ; Selliah, Subajini ; Shawgo, Rebecca S. ; Xu, Jinwang ; Chauret, Nathalie ; Berlioz-Seux, Francoise ; Chan, Laval C. ; Das, Sanjoy K. ; Grillot, Anne-Laure ; Bennani, Youssef L. ; Maxwell, John P.

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (4), p.940-943 [Periódico revisado por pares]

England: Elsevier Ltd

Texto completo disponível

Citações Citado por
4
Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors
Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors
Material Type:
Artigo 		Adicionar ao Meu Espaço

Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors

Giroux, Simon ; Xu, Jinwang ; Reddy, T. Jagadeeswar ; Morris, Mark ; Cottrell, Kevin M ; Cadilhac, Caroline ; Henderson, James A ; Nicolas, Oliver ; Bilimoria, Darius ; Denis, Francois ; Mani, Nagraj ; Ewing, Nigel ; Shawgo, Rebecca ; L’Heureux, Lucille ; Selliah, Subajini ; Chan, Laval ; Chauret, Nathalie ; Berlioz-Seux, Francoise ; Namchuk, Mark N ; Grillot, Anne-Laure ; Bennani, Youssef L ; Das, Sanjoy K ; Maxwell, John P

ACS medicinal chemistry letters, 2014-03, Vol.5 (3), p.240-243 [Periódico revisado por pares]

United States: American Chemical Society

Texto completo disponível

Citações Citado por

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.