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11
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Zheng, Qinheng ; Woehl, Jordan L. ; Kitamura, Seiya ; Santos-Martins, Diogo ; Smedley, Christopher J. ; Li, Gencheng ; Forli, Stefano ; Moses, John E. ; Wolan, Dennis W. ; Sharpless, K. Barry

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18808-18814 [Periódico revisado por pares]

United States: National Academy of Sciences

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12
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
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Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets

Sriram, Krishna ; Insel, Paul A

Physiological reviews, 2021-04, Vol.101 (2), p.545-567 [Periódico revisado por pares]

United States: American Physiological Society

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13
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
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Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases

Powers, James C ; Asgian, Juliana L ; Ekici, Özlem Doǧan ; James, Karen Ellis

Chemical reviews, 2002-12, Vol.102 (12), p.4639-4750 [Periódico revisado por pares]

United States: American Chemical Society

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14
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases
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Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

Park, Ji-Young ; Kim, Jang Hoon ; Kim, Young Min ; Jeong, Hyung Jae ; Kim, Dae Wook ; Park, Ki Hun ; Kwon, Hyung-Jun ; Park, Su-Jin ; Lee, Woo Song ; Ryu, Young Bae

Bioorganic & medicinal chemistry, 2012-10, Vol.20 (19), p.5928-5935 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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15
Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure‐Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects
Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure‐Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects
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Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure‐Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects

Palmér, Robert ; Mäenpää, Jukka ; Jauhiainen, Alexandra ; Larsson, Bengt ; Mo, John ; Russell, Muir ; Root, James ; Prothon, Susanne ; Chialda, Ligia ; Forte, Pablo ; Egelrud, Torbjörn ; Stenvall, Kristina ; Gardiner, Philip

Clinical pharmacology and therapeutics, 2018-12, Vol.104 (6), p.1155-1164 [Periódico revisado por pares]

United States: John Wiley and Sons Inc

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16
Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus
Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus
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Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus

Wang, Yan ; Wang, Baojie ; Liu, Mei ; Jiang, Keyong ; Wang, Mengqiang ; Wang, Lei

Developmental and comparative immunology, 2021-01, Vol.114, p.103871-103871, Article 103871 [Periódico revisado por pares]

United States: Elsevier Ltd

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17
A proteomic atlas of senescence-associated secretomes for aging biomarker development
A proteomic atlas of senescence-associated secretomes for aging biomarker development
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A proteomic atlas of senescence-associated secretomes for aging biomarker development

Basisty, Nathan ; Kale, Abhijit ; Jeon, Ok Hee ; Kuehnemann, Chisaka ; Payne, Therese ; Rao, Chirag ; Holtz, Anja ; Shah, Samah ; Sharma, Vagisha ; Ferrucci, Luigi ; Campisi, Judith ; Schilling, Birgit Serrano, Manuel

PLoS biology, 2020-01, Vol.18 (1), p.e3000599-e3000599 [Periódico revisado por pares]

United States: Public Library of Science

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18
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer
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Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer

Lyu, Peng ; Ge, Lilin ; Ma, Rui ; Wei, Ran ; McCrudden, Cian M ; Chen, Tianbao ; Shaw, Chris ; Kwok, Hang Fai

Scientific reports, 2018-09, Vol.8 (1), p.14502-10, Article 14502 [Periódico revisado por pares]

England: Nature Publishing Group

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19
Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)
Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)
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Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)

Rahman, Noor ; Basharat, Zarrin ; Yousuf, Muhammad ; Castaldo, Giuseppe ; Rastrelli, Luca ; Khan, Haroon

Molecules (Basel, Switzerland), 2020-05, Vol.25 (10), p.2271 [Periódico revisado por pares]

Switzerland: MDPI AG

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20
Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease
Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease
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Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease

Hollenberg, M D ; Mihara, K ; Polley, D ; Suen, J Y ; Han, A ; Fairlie, D P ; Ramachandran, R

British journal of pharmacology, 2014-03, Vol.171 (5), p.1180-1194 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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Deste Autor:

  1. Scheid, L
  2. Pozzatti, P
  3. Line, S
  4. Silveira, C
  5. Bollela, V

Neste Assunto:

  1. Science & Technology
  2. Life Sciences & Biomedicine
  3. Humans
  4. Animals
  5. Biological And Medical Sciences

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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