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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura ; Yuan, Shuofeng ; Yin, Xin ; Martin-Sancho, Laura ; Matsunaga, Naoko ; Pache, Lars ; Burgstaller-Muehlbacher, Sebastian ; De Jesus, Paul D ; Teriete, Peter ; Hull, Mitchell V ; Chang, Max W ; Chan, Jasper Fuk-Woo ; Cao, Jianli ; Poon, Vincent Kwok-Man ; Herbert, Kristina M ; Cheng, Kuoyuan ; Nguyen, Tu-Trinh H ; Rubanov, Andrey ; Pu, Yuan ; Nguyen, Courtney ; Choi, Angela ; Rathnasinghe, Raveen ; Schotsaert, Michael ; Miorin, Lisa ; Dejosez, Marion ; Zwaka, Thomas P ; Sit, Ko-Yung ; Martinez-Sobrido, Luis ; Liu, Wen-Chun ; White, Kris M ; Chapman, Mackenzie E ; Lendy, Emma K ; Glynne, Richard J ; Albrecht, Randy ; Ruppin, Eytan ; Mesecar, Andrew D ; Johnson, Jeffrey R ; Benner, Christopher ; Sun, Ren ; Schultz, Peter G ; Su, Andrew I ; García-Sastre, Adolfo ; Chatterjee, Arnab K ; Yuen, Kwok-Yung ; Chanda, Sumit K

Nature (London), 2020-10, Vol.586 (7827), p.113-119 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents
Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents
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Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents

Mody, Vicky ; Ho, Joanna ; Wills, Savannah ; Mawri, Ahmed ; Lawson, Latasha ; Ebert, Maximilian C C J C ; Fortin, Guillaume M ; Rayalam, Srujana ; Taval, Shashidharamurthy

Communications biology, 2021-01, Vol.4 (1), p.93-93, Article 93 [Periódico revisado por pares]

England: Nature Publishing Group

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3
A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
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A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases

Nishimiya, Daisuke ; Kawaguchi, Yoshirou ; Kodama, Shiho ; Nasu, Hatsumi ; Yano, Hidenori ; Yamaguchi, Aya ; Tamura, Masakazu ; Hashimoto, Ryuji

Scientific reports, 2019-08, Vol.9 (1), p.11436-11, Article 11436 [Periódico revisado por pares]

England: Nature Publishing Group

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Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4
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Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4

Kim, Solbi ; Ko, Dongjoon ; Lee, Yunhee ; Jang, Seonghui ; Lee, Younghoon ; Lee, Ill Young ; Kim, Semi

Scientific reports, 2019-07, Vol.9 (1), p.10003-13, Article 10003 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

Wettstein, Lukas ; Weil, Tatjana ; Conzelmann, Carina ; Müller, Janis A ; Groß, Rüdiger ; Hirschenberger, Maximilian ; Seidel, Alina ; Klute, Susanne ; Zech, Fabian ; Prelli Bozzo, Caterina ; Preising, Nico ; Fois, Giorgio ; Lochbaum, Robin ; Knaff, Philip Maximilian ; Mailänder, Volker ; Ständker, Ludger ; Thal, Dietmar Rudolf ; Schumann, Christian ; Stenger, Steffen ; Kleger, Alexander ; Lochnit, Günter ; Mayer, Benjamin ; Ruiz-Blanco, Yasser B ; Hoffmann, Markus ; Sparrer, Konstantin M J ; Pöhlmann, Stefan ; Sanchez-Garcia, Elsa ; Kirchhoff, Frank ; Frick, Manfred ; Münch, Jan

Nature communications, 2021-03, Vol.12 (1), p.1726-1726, Article 1726 [Periódico revisado por pares]

England: Nature Publishing Group

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6
NSP4, an elastase-related protease in human neutrophils with arginine specificity
NSP4, an elastase-related protease in human neutrophils with arginine specificity
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NSP4, an elastase-related protease in human neutrophils with arginine specificity

Perera, Natascha C ; Schilling, Oliver ; Kittel, Heike ; Back, Walter ; Kremmer, Elisabeth ; Jenne, Dieter E

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6229-6234 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Novel scabies mite serpins inhibit the three pathways of the human complement system
Novel scabies mite serpins inhibit the three pathways of the human complement system
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Novel scabies mite serpins inhibit the three pathways of the human complement system

Mika, Angela ; Reynolds, Simone L ; Mohlin, Frida C ; Willis, Charlene ; Swe, Pearl M ; Pickering, Darren A ; Halilovic, Vanja ; Wijeyewickrema, Lakshmi C ; Pike, Robert N ; Blom, Anna M ; Kemp, David J ; Fischer, Katja Benarafa, Charaf

PloS one, 2012-07, Vol.7 (7), p.e40489-e40489 [Periódico revisado por pares]

United States: Public Library of Science

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8
Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes
Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes
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Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes

An, Chunju ; Hiromasa, Yasuaki ; Zhang, Xin ; Lovell, Scott ; Zolkiewski, Michal ; Tomich, John M ; Michel, Kristin Dimopoulos, George

PloS one, 2012-11, Vol.7 (11), p.e48689-e48689 [Periódico revisado por pares]

United States: Public Library of Science

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9
New structural variants of aeruginosin produced by the toxic bloom forming cyanobacterium Nodularia spumigena
New structural variants of aeruginosin produced by the toxic bloom forming cyanobacterium Nodularia spumigena
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New structural variants of aeruginosin produced by the toxic bloom forming cyanobacterium Nodularia spumigena

Fewer, David P ; Jokela, Jouni ; Paukku, Eeva ; Österholm, Julia ; Wahlsten, Matti ; Permi, Perttu ; Aitio, Olli ; Rouhiainen, Leo ; Gomez-Saez, Gonzalo V ; Sivonen, Kaarina Harder, Tilmann

PloS one, 2013-09, Vol.8 (9), p.e73618 [Periódico revisado por pares]

United States: Public Library of Science

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10
SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms
SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms
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SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms

Chen, Zongyun ; Wang, Bin ; Hu, Jun ; Yang, Weishan ; Cao, Zhijian ; Zhuo, Renxi ; Li, Wenxin ; Wu, Yingliang Ho, Paulo Lee

PloS one, 2013-03, Vol.8 (3), p.e57529-e57529 [Periódico revisado por pares]

United States: Public Library of Science

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