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A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
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A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases

Nishimiya, Daisuke ; Kawaguchi, Yoshirou ; Kodama, Shiho ; Nasu, Hatsumi ; Yano, Hidenori ; Yamaguchi, Aya ; Tamura, Masakazu ; Hashimoto, Ryuji

Scientific reports, 2019-08, Vol.9 (1), p.11436-11, Article 11436 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

Wettstein, Lukas ; Weil, Tatjana ; Conzelmann, Carina ; Müller, Janis A ; Groß, Rüdiger ; Hirschenberger, Maximilian ; Seidel, Alina ; Klute, Susanne ; Zech, Fabian ; Prelli Bozzo, Caterina ; Preising, Nico ; Fois, Giorgio ; Lochbaum, Robin ; Knaff, Philip Maximilian ; Mailänder, Volker ; Ständker, Ludger ; Thal, Dietmar Rudolf ; Schumann, Christian ; Stenger, Steffen ; Kleger, Alexander ; Lochnit, Günter ; Mayer, Benjamin ; Ruiz-Blanco, Yasser B ; Hoffmann, Markus ; Sparrer, Konstantin M J ; Pöhlmann, Stefan ; Sanchez-Garcia, Elsa ; Kirchhoff, Frank ; Frick, Manfred ; Münch, Jan

Nature communications, 2021-03, Vol.12 (1), p.1726-1726, Article 1726 [Periódico revisado por pares]

England: Nature Publishing Group

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3
NSP4, an elastase-related protease in human neutrophils with arginine specificity
NSP4, an elastase-related protease in human neutrophils with arginine specificity
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NSP4, an elastase-related protease in human neutrophils with arginine specificity

Perera, Natascha C ; Schilling, Oliver ; Kittel, Heike ; Back, Walter ; Kremmer, Elisabeth ; Jenne, Dieter E

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6229-6234 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Novel scabies mite serpins inhibit the three pathways of the human complement system
Novel scabies mite serpins inhibit the three pathways of the human complement system
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Novel scabies mite serpins inhibit the three pathways of the human complement system

Mika, Angela ; Reynolds, Simone L ; Mohlin, Frida C ; Willis, Charlene ; Swe, Pearl M ; Pickering, Darren A ; Halilovic, Vanja ; Wijeyewickrema, Lakshmi C ; Pike, Robert N ; Blom, Anna M ; Kemp, David J ; Fischer, Katja Benarafa, Charaf

PloS one, 2012-07, Vol.7 (7), p.e40489-e40489 [Periódico revisado por pares]

United States: Public Library of Science

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5
Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes
Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes
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Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes

An, Chunju ; Hiromasa, Yasuaki ; Zhang, Xin ; Lovell, Scott ; Zolkiewski, Michal ; Tomich, John M ; Michel, Kristin Dimopoulos, George

PloS one, 2012-11, Vol.7 (11), p.e48689-e48689 [Periódico revisado por pares]

United States: Public Library of Science

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6
SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms
SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms
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SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms

Chen, Zongyun ; Wang, Bin ; Hu, Jun ; Yang, Weishan ; Cao, Zhijian ; Zhuo, Renxi ; Li, Wenxin ; Wu, Yingliang Ho, Paulo Lee

PloS one, 2013-03, Vol.8 (3), p.e57529-e57529 [Periódico revisado por pares]

United States: Public Library of Science

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7
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
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The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

Malaker, Stacy A. ; Pedram, Kayvon ; Ferracane, Michael J. ; Bensing, Barbara A. ; Krishnan, Venkatesh ; Pett, Christian ; Yu, Jin ; Woods, Elliot C. ; Kramer, Jessica R. ; Westerlind, Ulrika ; Dorigo, Oliver ; Bertozzi, Carolyn R.

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7278-7287 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
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Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Hander Tim ; Fernández-Fernández, Álvaro D ; Kumpf, Robert P ; Willems, Patrick ; Schatowitz Hendrik ; Rombaut Debbie ; Staes An ; Nolf Jonah ; Pottie, Robin ; Yao Panfeng ; Gonçalves, Amanda ; Pavie Benjamin ; Boller, Thomas ; Gevaert Kris ; Frank, Van Breusegem ; Bartels, Sebastian ; Stael Simon

Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6433) [Periódico revisado por pares]

Washington: The American Association for the Advancement of Science

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9
Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein
Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein
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Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein

Schmidt, Karin ; Gardill, Bernd R. ; Kern, Alina ; Kirchweger, Peter ; Börsch, Michael ; Muller, Yves A.

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.5744-5749 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Human FAM111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1
Human FAM111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1
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Human FAM111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1

Zhu, Junda ; Gao, Xintao ; Li, Yijing ; Zhang, Zihui ; Xie, Shijie ; Ren, Shuning ; Li, Yarui ; Li, Hua ; Niu, Kang ; Fu, Shufang ; Deng, Yining ; Li, Yinü ; Moss, Bernard ; Wu, Wenxue ; Peng, Chen

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (35), p.e2304242120-e2304242120 [Periódico revisado por pares]

United States: National Academy of Sciences

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