Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs

Sperling, Adam S. ; Burgess, Michael ; Keshishian, Hasmik ; Gasser, Jessica A. ; Bhatt, Shruti ; Jan, Max ; Słabicki, Mikołaj ; Sellar, Rob S. ; Fink, Emma C. ; Miller, Peter G. ; Liddicoat, Brian J. ; Sievers, Quinlan L. ; Sharma, Rohan ; Adams, Dylan N. ; Olesinski, Elyse A. ; Fulciniti, Mariateresa ; Udeshi, Namrata D. ; Kuhn, Eric ; Letai, Anthony ; Munshi, Nikhil C. ; Carr, Steven A. ; Ebert, Benjamin L.

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Modeling and targeting of erythroleukemia by hematopoietic genome editing

Iacobucci, Ilaria ; Qu, Chunxu ; Varotto, Elena ; Janke, Laura J. ; Yang, Xu ; Seth, Aman ; Shelat, Anang ; Friske, Jake D. ; Fukano, Reiji ; Yu, Jiyang ; Freeman, Burgess B. ; Kennedy, James A. ; Sperling, Adam S. ; Zheng, Rena ; Wang, Yingzhe ; Jogiraju, Harini ; Dickerson, Kirsten M. ; Payne-Turner, Debbie ; Morris, Sarah M. ; Hollis, Emily S. ; Ghosn, Nina ; Haggard, Georgia E. ; Lindsley, R. Coleman ; Ebert, Benjamin L. ; Mullighan, Charles G.

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Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms

Sperling, Adam S. ; Guerra, Veronica A. ; Kennedy, James A. ; Yan, Yuanqing ; Hsu, Joanne I. ; Wang, Feng ; Nguyen, Andrew T. ; Miller, Peter G. ; McConkey, Marie E. ; Quevedo Barrios, Vanessa A. ; Furudate, Ken ; Zhang, Linda ; Kanagal-Shamanna, Rashmi ; Zhang, Jianhua ; Little, Latasha ; Gumbs, Curtis ; Daver, Naval ; DiNardo, Courtney D. ; Kadia, Tapan ; Ravandi, Farhad ; Kantarjian, Hagop ; Garcia-Manero, Guillermo ; Futreal, P. Andrew ; Ebert, Benjamin L. ; Takahashi, Koichi

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Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML

Bourgeois, Wallace ; Cutler, Jevon A. ; Aubrey, Brandon J. ; Wenge, Daniela V. ; Perner, Florian ; Martucci, Cynthia ; Henrich, Jill A. ; Klega, Kelly ; Nowak, Radosław P. ; Donovan, Katherine A. ; Boileau, Meaghan ; Wen, Yanhe ; Hatton, Charlie ; Apazidis, Athina A. ; Olsen, Sarah Naomi ; Kirmani, Nadia ; Pikman, Yana ; Pollard, Jessica A. ; Perry, Jennifer A. ; Sperling, Adam S. ; Ebert, Benjamin L. ; McGeehan, Gerard M. ; Crompton, Brian D. ; Fischer, Eric S. ; Armstrong, Scott A.

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UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability

Tsai, Jonathan M ; Aguirre, Jacob D ; Brown, Jared ; Focht, Vivian ; Li, Yen-Der ; Kempf, Georg ; Kater, Lukas ; Galli, Pius ; Cavadini, Simone ; Sandoval, Brittany E ; Zou, Charles ; Rutter, Justine ; Donovan, Katherine ; Sievers, Quinlan ; Park, Paul ; Cutler, Jevon A. ; Hatton, Charlie ; Ener, Elizabeth ; Sperling, Micah T ; Slabicki, Mikolaj ; Miller, Peter G. ; Belizaire, Roger ; Sperling, Adam S. ; Armstrong, Scott A. ; Fischer, Eric S. ; Thomä, Nicolas ; Ebert, Benjamin L.

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Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Miller, Peter G. ; Qiao, Dandi ; Rojas-Quintero, Joselyn ; Honigberg, Michael C. ; Sperling, Adam S. ; Gibson, Christopher J. ; Bick, Alexander G. ; Niroula, Abhishek ; McConkey, Marie E. ; Sandoval, Brittany ; Miller, Brian C. ; Shi, Weiwei ; Viswanathan, Kaushik ; Leventhal, Matthew ; Werner, Lillian ; Moll, Matthew ; Cade, Brian E. ; Barr, R. Graham ; Correa, Adolfo ; Cupples, L. Adrienne ; Gharib, Sina A. ; Jain, Deepti ; Gogarten, Stephanie M. ; Lange, Leslie A. ; London, Stephanie J. ; Manichaikul, Ani ; O'Connor, George T. ; Oelsner, Elizabeth C. ; Redline, Susan ; Rich, Stephen S. ; Rotter, Jerome I. ; Ramachandran, Vasan ; Yu, Bing ; Sholl, Lynette ; Neuberg, Donna ; Jaiswal, Siddhartha ; Levy, Bruce D. ; Owen, Caroline A. ; Natarajan, Pradeep ; Silverman, Edwin K. ; van Galen, Peter ; Tesfaigzi, Yohannes ; Cho, Michael H. ; Ebert, Benjamin L.

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Burkitt lymphoma in the modern era: real-world outcomes and prognostication across 30 US cancer centers

Evens, Andrew M. ; Danilov, Alexey ; Jagadeesh, Deepa ; Sperling, Amy ; Kim, Seo-Hyun ; Vaca, Ryan ; Wei, Catherine ; Rector, Daniel ; Sundaram, Suchitra ; Reddy, Nishitha ; Lin, Yong ; Farooq, Umar ; D'Angelo, Christopher ; Bond, David A. ; Berg, Stephanie ; Churnetski, Michael C. ; Godara, Amandeep ; Khan, Nadia ; Choi, Yun Kyong ; Yazdy, Maryam ; Rabinovich, Emma ; Varma, Gaurav ; Karmali, Reem ; Mian, Agrima ; Savani, Malvi ; Burkart, Madelyn ; Martin, Peter ; Ren, Albert ; Chauhan, Ayushi ; Diefenbach, Catherine ; Straker-Edwards, Allandria ; Klein, Andreas K. ; Blum, Kristie A. ; Boughan, Kirsten Marie ; Smith, Scott E. ; Haverkos, Brad M. ; Orellana-Noia, Victor M. ; Kenkre, Vaishalee P. ; Zayac, Adam ; Ramdial, Jeremy ; Maliske, Seth M. ; Epperla, Narendranath ; Venugopal, Parameswaran ; Feldman, Tatyana A. ; Smith, Stephen D. ; Stadnik, Andrzej ; David, Kevin A. ; Naik, Seema ; Lossos, Izidore S. ; Lunning, Matthew A. ; Caimi, Paolo ; Kamdar, Manali ; Palmisiano, Neil ; Bachanova, Veronika ; Portell, Craig A. ; Phillips, Tycel ; Olszewski, Adam J. ; Alderuccio, Juan Pablo

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Analytical and Clinical Validation of Duoseq, a Novel Assay for Rapid, on-Site Clinical DNA and RNA Sequencing of Hematologic Malignancies

Hsi, Eric D. ; Czader, Magdalena ; Hill, Brian T. ; Thacker, Elizabeth ; Wang, Lin ; Giauque, Christopher ; Vrydaghs, Andrea ; Sperling, Matt ; Bouldin, Jordan ; Erno, Robert ; Happ, Lanie ; Parker, Clayton ; Love, Cassandra L. ; Shingleton, Jennifer ; Dave, Sandeep

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Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A -r and NPM1c AML

Bourgeois, Wallace ; Cutler, Jevon A. ; Aubrey, Brandon J ; Wenge, Daniela ; Perner, Florian ; Martucci, Cynthia ; Henrich, Jill A. ; Klega, Kelly ; Nowak, Radoslaw P ; Donovan, Katherine Aleisha ; Boileau, Meaghan ; Wen, Yanhe ; Hatton, Charles ; Apazidis, Athina A. ; Olsen, Sarah N. ; Kirmani, Nadia ; Pikman, Yana ; Pollard, Jessica A. ; Perry, Jennifer A. ; Sperling, Adam S. ; Ebert, Benjamin L ; McGeehan, Gerard M. ; Crompton, Brian D. ; Fischer, Eric S ; Armstrong, Scott A.

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Acalabrutinib in Combination with Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy in Relapsed/Refractory B-Cell Lymphoma: A Phase I/II Study of Safety, Efficacy and Immune Correlative Analysis

Poh, Christina ; Chow, Victor A ; Lynch, Ryan C ; Ujjani, Chaitra S ; Shadman, Mazyar ; Till, Brian G ; Raghunathan, Vikram ; Warren, Edus H ; Gauthier, Jordan ; Smith, Stephen D ; Gujral, Taran ; Morishima, Chihiro ; Wu, Qian ; Voutsinas, Jenna M ; Sperling, Amy ; Dizon, Joshua ; Maloney, David G ; Gopal, Ajay K

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