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Material Type: Artigo
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HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycleDEARDORFF, Matthew A ; BANDO, Masashige ; COLE, Kathryn E ; DE BAERE, Elfride ; DECROOS, Christophe ; DI DONATO, Nataliya ; ERNST, Sarah ; FRANCEY, Lauren J ; GYFTODIMOU, Yolanda ; HIRASHIMA, Kyotaro ; HULLINGS, Melanie ; ISHIKAWA, Yuuichi ; NAKATO, Ryuichiro ; JAULIN, Christian ; KAUR, Maninder ; KIYONO, Tohru ; LOMBARDI, Patrick M ; MAGNAGHI-JAULIN, Laura ; MORTIER, Geert R ; NOZAKI, Naohito ; PETERSEN, Michael B ; SEIMIYA, Hiroyuki ; SIU, Victoria M ; WATRIN, Erwan ; SUZUKI, Yutaka ; TAKAGAKI, Kentaro ; WILDE, Jonathan J ; WILLEMS, Patrick J ; PRIGENT, Claude ; GILLESSEN-KAESBACH, Gabriele ; CHRISTIANSON, David W ; KAISER, Frank J ; JACKSON, Laird G ; HIROTA, Toru ; ITOH, Takehiko ; KRANTZ, Ian D ; SHIRAHIGE, Katsuhiko ; MINAMINO, Masashi ; SAITOH, Katsuya ; KOMATA, Makiko ; KATOU, Yuki ; CLARK, DinahNature (London), 2012-09, Vol.489 (7415), p.313-317 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growthHATZIVASSILIOU, Georgia ; KYUNG SONG ; MORALES, Tony ; ALIAGAS, Ignacio ; BONNIE LIU ; SIDERIS, Steve ; HOEFLICH, Klaus P ; JAISWAL, Bijay S ; SESHAGIRI, Somasekar ; KOEPPEN, Hartmut ; BELVIN, Marcia ; FRIEDMAN, Lori S ; YEN, Ivana ; MALEK, Shiva ; BRANDHUBER, Barbara J ; ANDERSON, Daniel J ; ALVARADO, Ryan ; LUDLAM, Mary J. C ; STOKOE, David ; GLOOR, Susan L ; VIGERS, GuyNature (London), 2010-03, Vol.464 (7287), p.431-435 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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3 |
Material Type: Artigo
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The HSP90 Inhibitor XL888 Overcomes BRAF Inhibitor Resistance Mediated through Diverse MechanismsPARAISO, Kim H. T ; HAARBERG, H. Eirik ; JOHN, Jobin K ; SARNAIK, Amod A ; KOOMEN, John M ; SMALLEY, Keiran S. M ; WOOD, Elizabeth ; REBECCA, Vito W ; CHEN, Y. Ann ; YUN XIANG ; RIBAS, Antoni ; LO, Roger S ; WEBER, Jeffrey S ; SONDAK, Vernon KClinical cancer research, 2012-05, Vol.18 (9), p.2502-2514 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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4 |
Material Type: Artigo
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The serine threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cellsASANO, J ; NAKANO, A ; KAGAWA, K ; ENDO, I ; YATA, K ; SAKAI, A ; OZAKI, S ; MATSUMOTO, T ; ABE, M ; ODA, A ; AMOU, H ; HIASA, M ; TAKEUCHI, K ; MIKI, H ; NAKAMURA, S ; HARADA, T ; FUJII, SLeukemia, 2011-07, Vol.25 (7), p.1182-1188 [Periódico revisado por pares]Avenel, NJ: Nature Publishing GroupTexto completo disponível |
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5 |
Material Type: Artigo
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Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of CancerDE BACCO, Francesca ; LURAGHI, Paolo ; MEDICO, Enzo ; REATO, Gigliola ; GIROLAMI, Flavia ; PERERA, Timothy ; GABRIELE, Pietro ; COMOGLIO, Paolo M ; BOCCACCIO, CarlaJNCI : Journal of the National Cancer Institute, 2011-04, Vol.103 (8), p.645-661 [Periódico revisado por pares]Cary, NC: Oxford University PressTexto completo disponível |
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6 |
Material Type: Artigo
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Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and NoxaINOUE, S ; RILEY, J ; GANT, T. W ; DYER, M. J. S ; COHEN, G. MLeukemia, 2007-08, Vol.21 (8), p.1773-1782 [Periódico revisado por pares]London: Nature PublishingTexto completo disponível |
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7 |
Material Type: Artigo
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Identification of a Primary Target of Thalidomide TeratogenicityIto, Takumi ; Ando, Hideki ; Suzuki, Takayuki ; Ogura, Toshihiko ; Hotta, Kentaro ; Imamura, Yoshimasa ; Yamaguchi, Yuki ; Handa, HiroshiScience (American Association for the Advancement of Science), 2010-03, Vol.327 (5971), p.1345-1350 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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8 |
Material Type: Artigo
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Regulation of myeloid leukaemia by the cell-fate determinant MusashiGerrard, Gareth ; Lento, William E ; Lagoo, Anand ; Zimdahl, Bryan ; Blum, Jordan ; Radich, Jerald P ; Kwon, Hyog Young ; Congdon, Kendra L ; Chuah, Charles ; Oehler, Vivian G ; Kim, Dong-Wook ; Goh, Harriet ; Kim, Soo-Hyun ; Jordan, Craig T ; Zhao, Chen ; Foroni, Letizia ; Ito, Takahiro ; Reya, Tannishtha ; Goldman, JohnNature, 2010-08, Vol.466 (7307), p.765-768 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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9 |
Material Type: Artigo
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Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein BaxMCKENZIE, Mark D ; JAMIESON, Emma ; JANSEN, Elisa S ; SCOTT, Clare L ; HUANG, David C. S ; BOUILLET, Philippe ; ALLISON, Janette ; KAY, Thomas W. H ; STRASSER, Andreas ; THOMAS, Helen EDiabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.644-652 [Periódico revisado por pares]Alexandria, VA: American Diabetes AssociationTexto completo disponível |
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10 |
Material Type: Artigo
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Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsKOO, Bon-Kyoung ; SPIT, Maureen ; CLEVERS, Hans ; JORDENS, Ingrid ; LOW, Teck Y ; STANGE, Daniel E ; VAN DE WETERING, Marc ; ES, Johan H. Van ; MOHAMMED, Shabaz ; HECK, Albert J. R ; MAURICE, Madelon MNature (London), 2012-08, Vol.488 (7413), p.665-669 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |