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Mesothelin CAR-T cells expressing tumor-targeted immunocytokine IL-12 yield durable efficacy and fewer side effectsZhu, Yuankui ; Wang, Ke ; Yue, Linghe ; Zuo, Dianbao ; Sheng, Junfeng ; Lan, Sina ; Zhao, Zilong ; Dong, Shuang ; Hu, Sheng ; Chen, Xin ; Feng, MingqianPharmacological research, 2024-05, Vol.203, p.107186-107186, Article 107186 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Interleukin‐12 (IL‐12), but not IL‐23, induces the expression of IL‐7 in microglia and macrophages: implications for multiple sclerosisJana, Malabendu ; Mondal, Susanta ; Jana, Arundhati ; Pahan, KalipadaImmunology, 2014-04, Vol.141 (4), p.549-563 [Periódico revisado por pares]England: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Non-canonical interleukin 23 receptor complex assembly: p40 protein recruits interleukin 12 receptor β1 via site II and induces p19/interleukin 23 receptor interaction via site IIISchröder, Jutta ; Moll, Jens M ; Baran, Paul ; Grötzinger, Joachim ; Scheller, Jürgen ; Floss, Doreen MThe Journal of biological chemistry, 2015-01, Vol.290 (1), p.359-370 [Periódico revisado por pares]United States: American Society for Biochemistry and Molecular BiologyTexto completo disponível |
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Material Type: Artigo
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Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 VariantsHirschfield, Gideon M ; Liu, Xiangdong ; Xu, Chun ; Lu, Yan ; Lu, Yue ; Xie, Gang ; Gu, Xiangjun ; Walker, Erin J ; Jing, Kaiyan ; Juran, Brian D ; Mason, Andrew L ; Myers, Robert P ; Peltekian, Kevork M ; Ghent, Cameron N ; Coltescu, Catalina ; Atkinson, Elizabeth J ; Heathcote, E. Jenny ; Lazaridis, Konstantinos N ; Amos, Christopher I ; Siminovitch, Katherine AThe New England journal of medicine, 2009-06, Vol.360 (24), p.2544-2555 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
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Material Type: Artigo
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Genome-Wide Association Studies in Primary Biliary CirrhosisGulamhusein, Aliya F. ; Juran, Brian D. ; Lazaridis, Konstantinos N.Seminars in liver disease, 2015-11, Vol.35 (4), p.392-401 [Periódico revisado por pares]333 Seventh Avenue, New York, NY 10001, USA: Thieme Medical PublishersTexto completo disponível |
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Material Type: Artigo
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Consanguineous marriages increase the incidence of recurrent tuberculosis: Evidence from whole exome sequencingAkbar, Noor ul ; Ahmad, Sajjad ; Khan, Taj Ali ; Tayyeb, Muhammad ; Akhter, Naheed ; Shafiq, Laraib ; Khan, Shahid Niaz ; Alam, Mohammad Mahtab ; Abdullah, Alduwish Manal ; Rehman, Muhammad Fayyaz ur ; Bajaber, Majed A. ; Akram, Muhammad SafwanInfection, genetics and evolution, 2024-03, Vol.118, p.105559-105559, Article 105559 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12Lupardus, Patrick J. ; Garcia, K. ChristopherJournal of molecular biology, 2008-10, Vol.382 (4), p.931-941 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Nucleotide variation in IL‐10 and IL‐12 and their receptors and cervical and vulvar cancer risk: A hybrid case–parent triad and case–control studyHussain, Shehnaz K. ; Madeleine, Margaret M. ; Johnson, Lisa G. ; Du, Qin ; Galloway, Denise A. ; Daling, Janet R. ; Malkki, Mari ; Petersdorf, Effie W. ; Schwartz, Stephen M.International journal of cancer, 2013-07, Vol.133 (1), p.201-213 [Periódico revisado por pares]Hoboken, NJ: Wiley-BlackwellTexto completo disponível |
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Material Type: Artigo
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Associations between polymorphisms in IL-12A, IL-12B, IL-12Rβ1, IL-27 gene and serum levels of IL-12p40, IL-27p28 with esophageal cancerTao, Yi-Peng ; Wang, Wan-Ling ; Li, Song-Yue ; Zhang, Jian ; Shi, Qi-Zhong ; Zhao, Fen ; Zhao, Bao-ShengJournal of cancer research and clinical oncology, 2012-11, Vol.138 (11), p.1891-1900 [Periódico revisado por pares]Berlin/Heidelberg: Springer-VerlagTexto completo disponível |
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Material Type: Artigo
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Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transductionGeorgy, Jacqueline ; Arlt, Yvonne ; Moll, Jens M. ; Ouzin, Meryem ; Weitz, Hendrik T. ; Gremer, Lothar ; Willbold, Dieter ; Grötzinger, Joachim ; Thives-Kurenbach, Felix ; Scheller, Jürgen ; Floss, Doreen M.The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101295-101295, Article 101295 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |