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1
Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance
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Artigo
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Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance

TSUKUMO, Daniela M. L ; CARVALHO-FILHO, Marco A ; SAAD, Mario J. A ; CARVALHEIRA, José B. C ; PRADA, Patricia O ; HIRABARA, Sandro M ; SCHENKA, André A ; ARAUJO, Eliana P ; VASSALLO, José ; CURI, Rui ; VELLOSO, Licio A

Diabetes (New York, N.Y.), 2007-08, Vol.56 (8), p.1986-1998 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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2
Notch controls the survival of memory CD4+ T cells by regulating glucose uptake
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Artigo
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Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

Maekawa, Yoichi ; Ishifune, Chieko ; Tsukumo, Shin-ichi ; Hozumi, Katsuto ; Yagita, Hideo ; Yasutomo, Koji

Nature medicine, 2015-01, Vol.21 (1), p.55-61 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Bach2 maintains T cells in a naive state by suppressing effector memory-related genes
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Artigo
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Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

Tsukumo, Shin-ichi ; Unno, Midori ; Muto, Akihiko ; Takeuchi, Arata ; Kometani, Kohei ; Kurosaki, Tomohiro ; Igarashi, Kazuhiko ; Saito, Takashi

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10735-10740 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis
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Artigo
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A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis

Takezaki, Akio ; Tsukumo, Shin-Ichi ; Setoguchi, Yasuhiro ; Ledford, Julie G ; Goto, Hisatsugu ; Hosomichi, Kazuyoshi ; Uehara, Hisanori ; Nishioka, Yasuhiko ; Yasutomo, Koji

The Journal of experimental medicine, 2019-12, Vol.216 (12), p.2724-2735 [Periódico revisado por pares]

United States: Rockefeller University Press

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5
Slicer function of Drosophila Argonautes and its involvement in RISC formation
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Artigo
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Slicer function of Drosophila Argonautes and its involvement in RISC formation

Miyoshi, Keita ; Tsukumo, Hiroko ; Nagami, Tomoko ; Siomi, Haruhiko ; Siomi, Mikiko C

Genes & development, 2005-12, Vol.19 (23), p.2837-2848 [Periódico revisado por pares]

United States: Cold Spring Harbor Laboratory Press

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6
Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression
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Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression

Zaman, Taskia Sultana ; Arimochi, Hideki ; Maruyama, Satoshi ; Ishifune, Chieko ; Tsukumo, Shin-Ichi ; Kitamura, Akiko ; Yasutomo, Koji

The Journal of immunology (1950), 2017-09, Vol.199 (6), p.1989-1997 [Periódico revisado por pares]

United States: American Association of Immunologists

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7
La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)
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La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)

Fonseca, Bruno D. ; Zakaria, Chadi ; Jia, Jian-Jun ; Graber, Tyson E. ; Svitkin, Yuri ; Tahmasebi, Soroush ; Healy, Danielle ; Hoang, Huy-Dung ; Jensen, Jacob M. ; Diao, Ilo T. ; Lussier, Alexandre ; Dajadian, Christopher ; Padmanabhan, Niranjan ; Wang, Walter ; Matta-Camacho, Edna ; Hearnden, Jaclyn ; Smith, Ewan M. ; Tsukumo, Yoshinori ; Yanagiya, Akiko ; Morita, Masahiro ; Petroulakis, Emmanuel ; González, Jose L. ; Hernández, Greco ; Alain, Tommy ; Damgaard, Christian K.

The Journal of biological chemistry, 2015-06, Vol.290 (26), p.15996-16020 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Escape of malaria parasites from host immunity requires CD4 + CD25 + regulatory T cells
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Escape of malaria parasites from host immunity requires CD4 + CD25 + regulatory T cells

Yasutomo, Koji ; Hisaeda, Hajime ; Maekawa, Yoichi ; Iwakawa, Daiji ; Okada, Hiroko ; Himeno, Kunisuke ; Kishihara, Kenji ; Tsukumo, Shin-ichi

Nature medicine, 2004-01, Vol.10 (1), p.29-30 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells
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Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells

Ishifune, Chieko ; Tsukumo, Shin-Ichi ; Maekawa, Yoichi ; Hozumi, Katsuto ; Chung, Doo Hyun ; Motozono, Chihiro ; Yamasaki, Sho ; Nakano, Hiroyasu ; Yasutomo, Koji Oliver, Paula M.

PLoS biology, 2019-05, Vol.17 (5), p.e3000262-e3000262 [Periódico revisado por pares]

United States: Public Library of Science

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10
Development of a potent small‐molecule degrader against oncogenic BRAFV600E protein that evades paradoxical MAPK activation
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Development of a potent small‐molecule degrader against oncogenic BRAFV600E protein that evades paradoxical MAPK activation

Ohoka, Nobumichi ; Suzuki, Masanori ; Uchida, Takuya ; Tsukumo, Yoshinori ; Yoshida, Masayuki ; Inoue, Takao ; Ohki, Hitoshi ; Naito, Mikihiko

Cancer science, 2022-08, Vol.113 (8), p.2828-2838 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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