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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth
Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth
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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

Kleffel, Sonja ; Posch, Christian ; Barthel, Steven R. ; Mueller, Hansgeorg ; Schlapbach, Christoph ; Guenova, Emmanuella ; Elco, Christopher P. ; Lee, Nayoung ; Juneja, Vikram R. ; Zhan, Qian ; Lian, Christine G. ; Thomi, Rahel ; Hoetzenecker, Wolfram ; Cozzio, Antonio ; Dummer, Reinhard ; Mihm, Martin C. ; Flaherty, Keith T. ; Frank, Markus H. ; Murphy, George F. ; Sharpe, Arlene H. ; Kupper, Thomas S. ; Schatton, Tobias

Cell, 2015-09, Vol.162 (6), p.1242-1256 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
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Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice

Spencer, Alexandra J ; McKay, Paul F ; Belij-Rammerstorfer, Sandra ; Ulaszewska, Marta ; Bissett, Cameron D ; Hu, Kai ; Samnuan, Karnyart ; Blakney, Anna K ; Wright, Daniel ; Sharpe, Hannah R ; Gilbride, Ciaran ; Truby, Adam ; Allen, Elizabeth R ; Gilbert, Sarah C ; Shattock, Robin J ; Lambe, Teresa

Nature communications, 2021-05, Vol.12 (1), p.2893-2893, Article 2893 [Periódico revisado por pares]

England: Nature Publishing Group

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3
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
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PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

Tan, Catherine L ; Kuchroo, Juhi R ; Sage, Peter T ; Liang, Dan ; Francisco, Loise M ; Buck, Jessica ; Thaker, Youg Raj ; Zhang, Qianxia ; McArdel, Shannon L ; Juneja, Vikram R ; Lee, Sun Jung ; Lovitch, Scott B ; Lian, Christine ; Murphy, George F ; Blazar, Bruce R ; Vignali, Dario A A ; Freeman, Gordon J ; Sharpe, Arlene H

The Journal of experimental medicine, 2021-01, Vol.218 (1) [Periódico revisado por pares]

United States: Rockefeller University Press

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4
A Sertoli Cell-Selective Knockout of the Androgen Receptor Causes Spermatogenic Arrest in Meiosis
A Sertoli Cell-Selective Knockout of the Androgen Receptor Causes Spermatogenic Arrest in Meiosis
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A Sertoli Cell-Selective Knockout of the Androgen Receptor Causes Spermatogenic Arrest in Meiosis

De Gendt, Karel ; Swinnen, Johannes V. ; Philippa T. K. Saunders ; Schoonjans, Luc ; Dewerchin, Mieke ; Devos, Ann ; Tan, Karen ; Atanassova, Nina ; Claessens, Frank ; Lécureuil, Charlotte ; Heyns, Walter ; Carmeliet, Peter ; Guillou, Florian ; Sharpe, Richard M. ; Verhoeven, Guido

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (5), p.1327-1332 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
PD-1 Dependent Exhaustion of CD8+ T Cells Drives Chronic Malaria
PD-1 Dependent Exhaustion of CD8+ T Cells Drives Chronic Malaria
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PD-1 Dependent Exhaustion of CD8+ T Cells Drives Chronic Malaria

Horne-Debets, Joshua M. ; Faleiro, Rebecca ; Karunarathne, Deshapriya S. ; Liu, Xue Q. ; Lineburg, Katie E. ; Poh, Chek Meng ; Grotenbreg, Gijsbert M. ; Hill, Geoffrey R. ; MacDonald, Kelli P.A. ; Good, Michael F. ; Renia, Laurent ; Ahmed, Rafi ; Sharpe, Arlene H. ; Wykes, Michelle N.

Cell reports (Cambridge), 2013-12, Vol.5 (5), p.1204-1213 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
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Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

Reardon, David A ; Gokhale, Prafulla C ; Klein, Sarah R ; Ligon, Keith L ; Rodig, Scott J ; Ramkissoon, Shakti H ; Jones, Kristen L ; Conway, Amy Saur ; Liao, Xiaoyun ; Zhou, Jun ; Wen, Patrick Y ; Van Den Abbeele, Annick D ; Hodi, F Stephen ; Qin, Lei ; Kohl, Nancy E ; Sharpe, Arlene H ; Dranoff, Glenn ; Freeman, Gordon J

Cancer immunology research, 2016-02, Vol.4 (2), p.124-135 [Periódico revisado por pares]

United States

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7
PTPN2 regulates the generation of exhausted CD8 + T cell subpopulations and restrains tumor immunity
PTPN2 regulates the generation of exhausted CD8 + T cell subpopulations and restrains tumor immunity
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PTPN2 regulates the generation of exhausted CD8 + T cell subpopulations and restrains tumor immunity

LaFleur, Martin W ; Nguyen, Thao H ; Coxe, Matthew A ; Miller, Brian C ; Yates, Kathleen B ; Gillis, Jacob E ; Sen, Debattama R ; Gaudiano, Emily F ; Al Abosy, Rose ; Freeman, Gordon J ; Haining, W Nicholas ; Sharpe, Arlene H

Nature immunology, 2019-10, Vol.20 (10), p.1335-1347 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
Heparin is essential for the storage of specific granule proteases in mast cells
Heparin is essential for the storage of specific granule proteases in mast cells
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Heparin is essential for the storage of specific granule proteases in mast cells

Humphries, Donald E ; Stevens, Richard L ; Wong, Guang W ; Friend, Daniel S ; Gurish, Michael F ; Qiu, Wen-Tao ; Huang, Chifu ; Sharpe, Arlene H

Nature (London), 1999-08, Vol.400 (6746), p.769-772 [Periódico revisado por pares]

London: Nature Publishing

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9
Oncometabolite d-2HG alters T cell metabolism to impair CD8 + T cell function
Oncometabolite d-2HG alters T cell metabolism to impair CD8 + T cell function
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Oncometabolite d-2HG alters T cell metabolism to impair CD8 + T cell function

Notarangelo, Giulia ; Spinelli, Jessica B ; Perez, Elizabeth M ; Baker, Gregory J ; Kurmi, Kiran ; Elia, Ilaria ; Stopka, Sylwia A ; Baquer, Gerard ; Lin, Jia-Ren ; Golby, Alexandra J ; Joshi, Shakchhi ; Baron, Heide F ; Drijvers, Jefte M ; Georgiev, Peter ; Ringel, Alison E ; Zaganjor, Elma ; McBrayer, Samuel K ; Sorger, Peter K ; Sharpe, Arlene H ; Wucherpfennig, Kai W ; Santagata, Sandro ; Agar, Nathalie Y R ; Suvà, Mario L ; Haigis, Marcia C

Science (American Association for the Advancement of Science), 2022-09, Vol.377 (6614), p.1519-1529 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction
Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction
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Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction

Pellegrini, Hannah ; Sharpe, Elizabeth H. ; Liu, Guangyi ; Nishiuchi, Eiko ; Doerr, Nicholas ; Kipp, Kevin R. ; Chin, Tiffany ; Schimmel, Margaret F. ; Weimbs, Thomas

The Journal of biological chemistry, 2023-09, Vol.299 (9), p.105158-105158, Article 105158 [Periódico revisado por pares]

United States: Elsevier Inc

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