High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer

Rogic, Anita ; Pant, Ila ; Grumolato, Luca ; Fernandez-Rodriguez, Ruben ; Edwards, Andrew ; Das, Suvendu ; Sun, Aaron ; Yao, Shen ; Qiao, Rui ; Jaffer, Shabnam ; Sachidanandam, Ravi ; Akturk, Guray ; Karlic, Rosa ; Skobe, Mihaela ; Aaronson, Stuart A

England: Nature Publishing Group

Texto completo disponível

Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing

Wang, Li ; Sfakianos, John P ; Beaumont, Kristin G ; Akturk, Guray ; Horowitz, Amir ; Sebra, Robert P ; Farkas, Adam M ; Gnjatic, Sacha ; Hake, Austin ; Izadmehr, Sudeh ; Wiklund, Peter ; Oh, William K ; Szabo, Peter M ; Wind-Rotolo, Megan ; Unsal-Kacmaz, Keziban ; Yao, Xin ; Schadt, Eric ; Sharma, Padmanee ; Bhardwaj, Nina ; Zhu, Jun ; Galsky, Matthew D

United States

Texto completo disponível

BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology

Bigenwald, Camille ; Le Berichel, Jessica ; Wilk, C. Matthias ; Chakraborty, Rikhia ; Chen, Steven T. ; Tabachnikova, Alexandra ; Mancusi, Rebecca ; Abhyankar, Harshal ; Casanova-Acebes, Maria ; Laface, Ilaria ; Akturk, Guray ; Jobson, Jenielle ; Karoulia, Zoi ; Martin, Jerome C. ; Grout, John ; Rafiei, Anahita ; Lin, Howard ; Manz, Markus G. ; Baccarini, Alessia ; Poulikakos, Poulikos I. ; Brown, Brian D. ; Gnjatic, Sacha ; Lujambio, Amaia ; McClain, Kenneth L. ; Picarsic, Jennifer ; Allen, Carl E. ; Merad, Miriam

New York: Nature Publishing Group

Texto completo disponível

1309 Deep learning reveals predictive immune signature of response to checkpoint blockade in multiplexed spatial immunohistochemistry data

Sidhom, John-William ; Anker, Jonathan ; Akturk, Guray ; Izadmehr, Sudeh ; David, Justin ; Gupta, Saurabh ; Kim-Schulze, Seunghee ; Sharma, Padmanee ; Gnjatic, Sacha ; Galsky, Matthew

London: BMJ Publishing Group Ltd

Texto completo disponível

1465 Multiplex imaging identifies unique immunophenotypic and spatial characteristics associated with response to immune checkpoint inhibitors (ICIs) in metastatic urothelial cancer (mUC)

Anker, Jonathan ; Sidhom, John-William ; Akturk, Guray ; Izadmehr, Sudeh ; David, Justin ; Gupta, Saurabh ; Kim-Schulze, Seunghee ; Sharma, Padmanee ; Gnjatic, Sacha ; Galsky, Matthew

London: BMJ Publishing Group Ltd

Texto completo disponível

Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis

Akturk, Guray ; Sweeney, Robert ; Remark, Romain ; Merad, Miriam ; Gnjatic, Sacha

New York, NY: Springer New York

Sem texto completo

Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages

Hughes, Kelly ; Akturk, Guray ; Gnjatic, Sacha ; Chen, Benjamin ; Klotman, Mary ; Blasi, Maria

England: Copyright Wolters Kluwer Health, Inc

Texto completo disponível

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

Martin, Jerome C. ; Chang, Christie ; Boschetti, Gilles ; Ungaro, Ryan ; Giri, Mamta ; Grout, John A. ; Gettler, Kyle ; Chuang, Ling-shiang ; Nayar, Shikha ; Greenstein, Alexander J. ; Dubinsky, Marla ; Walker, Laura ; Leader, Andrew ; Fine, Jay S. ; Whitehurst, Charles E. ; Mbow, M Lamine ; Kugathasan, Subra ; Denson, Lee A. ; Hyams, Jeffrey S. ; Friedman, Joshua R. ; Desai, Prerak T. ; Ko, Huaibin M. ; Laface, Ilaria ; Akturk, Guray ; Schadt, Eric E. ; Salmon, Helene ; Gnjatic, Sacha ; Rahman, Adeeb H. ; Merad, Miriam ; Cho, Judy H. ; Kenigsberg, Ephraim

United States: Elsevier Inc

Texto completo disponível

Spatial CRISPR genomics identifies regulators of the tumor microenvironment

Dhainaut, Maxime ; Rose, Samuel A. ; Akturk, Guray ; Wroblewska, Aleksandra ; Nielsen, Sebastian R. ; Park, Eun Sook ; Buckup, Mark ; Roudko, Vladimir ; Pia, Luisanna ; Sweeney, Robert ; Le Berichel, Jessica ; Wilk, C. Matthias ; Bektesevic, Anela ; Lee, Brian H. ; Bhardwaj, Nina ; Rahman, Adeeb H. ; Baccarini, Alessia ; Gnjatic, Sacha ; Pe’er, Dana ; Merad, Miriam ; Brown, Brian D.

United States: Elsevier Inc

Texto completo disponível

Abstract PO-140: Unsupervised clustering and data modeling reveals molecular signatures linked a distinct African American enriched cluster with higher probability of death in triple negative breast cancer

Gonzalez-Kozlova, Edgar ; Chalumeau, Clelia ; LaFace, Ilaria ; Shapiro, Charles ; Akturk, Guray ; Del Valle, Diane Marie ; Gnjatic, Sacha

Texto completo disponível