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LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS -Mutant Lung Adenocarcinoma
LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS -Mutant Lung Adenocarcinoma
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LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS -Mutant Lung Adenocarcinoma

Galan-Cobo, Ana ; Sitthideatphaiboon, Piyada ; Qu, Xiao ; Poteete, Alissa ; Pisegna, Marlese A ; Tong, Pan ; Chen, Pei-Hsuan ; Boroughs, Lindsey K ; Rodriguez, Mirna L M ; Zhang, Winter ; Parlati, Francesco ; Wang, Jing ; Gandhi, Varsha ; Skoulidis, Ferdinandos ; DeBerardinis, Ralph J ; Minna, John D ; Heymach, John V

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13), p.3251-3267 [Periódico revisado por pares]

United States

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2
CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib
CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib
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CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib

Sen, Triparna ; Tong, Pan ; Stewart, C Allison ; Cristea, Sandra ; Valliani, Aly ; Shames, David S ; Redwood, Abena B ; Fan, You Hong ; Li, Lerong ; Glisson, Bonnie S ; Minna, John D ; Sage, Julien ; Gibbons, Don L ; Piwnica-Worms, Helen ; Heymach, John V ; Wang, Jing ; Byers, Lauren Averett

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (14), p.3870-3884 [Periódico revisado por pares]

United States: American Association for Cancer Research, Inc

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3
Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis
Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis
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Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis

Yan, Xiang ; Zhang, Xiaoshan ; Wang, Li ; Zhang, Ran ; Pu, Xingxiang ; Wu, Shuhong ; Li, Lei ; Tong, Pan ; Wang, Jing ; Meng, Qing H ; Jensen, Vanessa B ; Girard, Luc ; Minna, John D ; Roth, Jack A ; Swisher, Stephen G ; Heymach, John V ; Fang, Bingliang

Cancer research (Chicago, Ill.), 2019-01, Vol.79 (1), p.125-132 [Periódico revisado por pares]

United States

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4
STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment
STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment
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STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

Koyama, Shohei ; Akbay, Esra A ; Li, Yvonne Y ; Aref, Amir R ; Skoulidis, Ferdinandos ; Herter-Sprie, Grit S ; Buczkowski, Kevin A ; Liu, Yan ; Awad, Mark M ; Denning, Warren L ; Diao, Lixia ; Wang, Jing ; Parra-Cuentas, Edwin R ; Wistuba, Ignacio I ; Soucheray, Margaret ; Thai, Tran ; Asahina, Hajime ; Kitajima, Shunsuke ; Altabef, Abigail ; Cavanaugh, Jillian D ; Rhee, Kevin ; Gao, Peng ; Zhang, Haikuo ; Fecci, Peter E ; Shimamura, Takeshi ; Hellmann, Matthew D ; Heymach, John V ; Hodi, F Stephen ; Freeman, Gordon J ; Barbie, David A ; Dranoff, Glenn ; Hammerman, Peter S ; Wong, Kwok-Kin

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (5), p.999-1008 [Periódico revisado por pares]

United States

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5
CXCR2 Expression in Tumor Cells is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma
CXCR2 Expression in Tumor Cells is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma
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CXCR2 Expression in Tumor Cells is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma

SAINTIGNY, Pierre ; MASSARELLI, Erminia ; LIZHANG ; YUAN PING ; BEHRENS, Carmen ; SOLIS SOTO, Luisa M ; HEYMACH, John V ; KIM, Edward S ; HERBST, Roy S ; LIPPMAN, Scott M ; WISTUBA, Ignacio I ; KI HONG, Waun ; LIN, Steven ; KURIE, Jonathan M ; JA SEOK KOO ; AHN, Young-Ho ; YULONG CHEN ; GOSWAMI, Sangeeta ; EREZ, Baruch ; O'REILLY, Michael S ; DIANELIU ; JACK LEE, J

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (2), p.571-582 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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6
The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
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The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA

RABELLINO, Andrea ; CARTER, Brandon ; PAOLO SCAGLIONI, Pier ; KONSTANTINIDOU, Georgia ; WU, Shwu-Yuan ; RIMESSI, Alessandro ; BYERS, Lauren A ; HEYMACH, John V ; GIRARD, Luc ; CHIANG, Cheng-Ming ; TERUYA-FELDSTEIN, Julie

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2275-2284 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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7
Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection
Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection
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Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection

Tummers, Willemieke S ; Warram, Jason M ; Tipirneni, Kiranya E ; Fengler, John ; Jacobs, Paula ; Shankar, Lalitha ; Henderson, Lori ; Ballard, Betsy ; Pfefer, T Joshua ; Pogue, Brian W ; Weichert, Jamey P ; Bouvet, Michael ; Sorger, Jonathan ; Contag, Christopher H ; Frangioni, John V ; Tweedle, Michael F ; Basilion, James P ; Gambhir, Sanjiv S ; Rosenthal, Eben L

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (9), p.2197-2206 [Periódico revisado por pares]

United States: American Association for Cancer Research, Inc

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8
PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib
PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib
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PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib

ENGELMAN, Jeffrey A ; ZEJNULLAHU, Kreshnik ; ALTHAUS, Irene W ; GANDHI, Leena ; SHAPIRO, Geoffrey I ; NELSON, James M ; HEYMACH, John V ; MEYERSON, Matthew ; WONG, Kwok-Kin ; JÄNNE, Pasi A ; GALE, Christopher-Michael ; LIFSHITS, Eugene ; GONZALES, Andrea J ; SHIMAMURA, Takeshi ; FENG ZHAO ; VINCENT, Patrick W ; NAUMOV, George N ; BRADNER, James E

Cancer research (Chicago, Ill.), 2007-12, Vol.67 (24), p.11924-11932 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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9
Transcription Factor KLF11 Integrates Progesterone Receptor Signaling and Proliferation in Uterine Leiomyoma Cells
Transcription Factor KLF11 Integrates Progesterone Receptor Signaling and Proliferation in Uterine Leiomyoma Cells
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Transcription Factor KLF11 Integrates Progesterone Receptor Signaling and Proliferation in Uterine Leiomyoma Cells

PING YIN ; ZHIHONG LIN ; KIM, J. Julie ; CHAKRAVARTI, Debabrata ; BULUN, Serdar E ; REIERSTAD, Scott ; JU WU ; ISHIKAWA, Hiroshi ; MARSH, Erica E ; INNES, Joy ; YOUHONG CHENG ; PEARSON, Kerry ; SAYLER COON V, John

Cancer research (Chicago, Ill.), 2010-02, Vol.70 (4), p.1722-1730 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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10
Plasma Cytokine and Angiogenic Factor Profiling Identifies Markers Associated with Tumor Shrinkage in Early-Stage Non-Small Cell Lung Cancer Patients Treated with Pazopanib
Plasma Cytokine and Angiogenic Factor Profiling Identifies Markers Associated with Tumor Shrinkage in Early-Stage Non-Small Cell Lung Cancer Patients Treated with Pazopanib
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Plasma Cytokine and Angiogenic Factor Profiling Identifies Markers Associated with Tumor Shrinkage in Early-Stage Non-Small Cell Lung Cancer Patients Treated with Pazopanib

NIKOLINAKOS, Petros G ; ALTORKI, Nasser ; YANKELEVITZ, David ; TRAN, Hai T ; SHAOYU YAN ; RAJAGOPALAN, Dilip ; BORDOGNA, Walter ; OTTESEN, Lone H ; HEYMACH, John V

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2171-2179 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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