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11
JAK mutations in high-risk childhood acute lymphoblastic leukemia
JAK mutations in high-risk childhood acute lymphoblastic leukemia
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JAK mutations in high-risk childhood acute lymphoblastic leukemia

Mullighan, Charles G ; Zhang, Jinghui ; Harvey, Richard C ; Collins-Underwood, J. Racquel ; Schulman, Brenda A ; Phillips, Letha A ; Tasian, Sarah K ; Loh, Mignon L ; Su, Xiaoping ; Liu, Wei ; Devidas, Meenakshi ; Atlas, Susan R ; Chen, I. Ming ; Clifford, Robert J ; Gerhard, Daniela S ; Carroll, William L ; Reaman, Gregory H ; Smith, Malcolm ; Downing, James R ; Hunger, Stephen P ; Willman, Cheryl L

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9414-9418 [Peer Reviewed Journal]

United States: National Academy of Sciences

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12
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
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Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Garcia-Diaz, Angel ; Shin, Daniel Sanghoon ; Moreno, Blanca Homet ; Saco, Justin ; Escuin-Ordinas, Helena ; Rodriguez, Gabriel Abril ; Zaretsky, Jesse M. ; Sun, Lu ; Hugo, Willy ; Wang, Xiaoyan ; Parisi, Giulia ; Saus, Cristina Puig ; Torrejon, Davis Y. ; Graeber, Thomas G. ; Comin-Anduix, Begonya ; Hu-Lieskovan, Siwen ; Damoiseaux, Robert ; Lo, Roger S. ; Ribas, Antoni

Cell reports (Cambridge), 2017-05, Vol.19 (6), p.1189-1201 [Peer Reviewed Journal]

United States: Elsevier Inc

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13
Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial
Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial
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Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial

Reich, Kristian ; Kabashima, Kenji ; Peris, Ketty ; Silverberg, Jonathan I ; Eichenfield, Lawrence F ; Bieber, Thomas ; Kaszuba, Aleksandra ; Kolodsick, Jill ; Yang, Fan E ; Gamalo, Margaret ; Brinker, Dennis R ; DeLozier, Amy M ; Janes, Jonathan M ; Nunes, Fabio P ; Thyssen, Jacob P ; Simpson, Eric L

Archives of dermatology (1960), 2020-12, Vol.156 (12), p.1333-1343 [Peer Reviewed Journal]

United States: American Medical Association

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14
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
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African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

Li, Dan ; Zhang, Jing ; Yang, Wenping ; Li, Pan ; Ru, Yi ; Kang, Weifang ; Li, LuLu ; Ran, Yong ; Zheng, Haixue

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101190-101190, Article 101190 [Peer Reviewed Journal]

United States: Elsevier Inc

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15
Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients
Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients
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Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

Kim, Hanna ; Brooks, Kristina M. ; Tang, Cheng Cai ; Wakim, Paul ; Blake, Mary ; Brooks, Stephen R. ; Montealegre Sanchez, Gina A. ; de Jesus, Adriana A. ; Huang, Yan ; Tsai, Wanxia Li ; Gadina, Massimo ; Prakash, Apurva ; Janes, Jonathan Marcus ; Zhang, Xin ; Macias, William L. ; Kumar, Parag ; Goldbach‐Mansky, Raphaela

Clinical pharmacology and therapeutics, 2018-08, Vol.104 (2), p.364-373 [Peer Reviewed Journal]

United States

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16
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
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Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation

Glassman, Caleb R ; Tsutsumi, Naotaka ; Saxton, Robert A ; Lupardus, Patrick J ; Jude, Kevin M ; Garcia, K Christopher

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6589), p.163-169 [Peer Reviewed Journal]

United States: The American Association for the Advancement of Science

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17
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma

Biffi, Giulia ; Oni, Tobiloba E ; Spielman, Benjamin ; Hao, Yuan ; Elyada, Ela ; Park, Youngkyu ; Preall, Jonathan ; Tuveson, David A

Cancer discovery, 2019-02, Vol.9 (2), p.282-301

United States

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18
Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway
Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway

Ollila, Saara ; Domènech-Moreno, Eva ; Laajanen, Kaisa ; Wong, Iris Pl ; Tripathi, Sushil ; Pentinmikko, Nalle ; Gao, Yajing ; Yan, Yan ; Niemelä, Elina H ; Wang, Timothy C ; Viollet, Benoit ; Leone, Gustavo ; Katajisto, Pekka ; Vaahtomeri, Kari ; Mäkelä, Tomi P

The Journal of clinical investigation, 2018-01, Vol.128 (1), p.402-414 [Peer Reviewed Journal]

United States: American Society for Clinical Investigation

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19
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
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JAK2 inhibitors for myeloproliferative neoplasms: what is next?

Bose, Prithviraj ; Verstovsek, Srdan

Blood, 2017-07, Vol.130 (2), p.115-125 [Peer Reviewed Journal]

United States: Elsevier Inc

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20
JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms
JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms
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JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms

Parampalli Yajnanarayana, Sowmya ; Stübig, Thomas ; Cornez, Isabelle ; Alchalby, Haefaa ; Schönberg, Kathrin ; Rudolph, Janna ; Triviai, Ioanna ; Wolschke, Christine ; Heine, Annkristin ; Brossart, Peter ; Kröger, Nicolaus ; Wolf, Dominik

British journal of haematology, 2015-06, Vol.169 (6), p.824-833 [Peer Reviewed Journal]

England

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