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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, Edit ; Tripolt, Sabrina ; Hoelbl-Kovacic, Andrea ; Gisslinger, Bettina ; Bago-Horvath, Zsuzsanna ; Casanova-Hevia, Emilio ; Clappier, Emmanuelle ; Decker, Thomas ; Fajmann, Sabine ; Fux, Daniela A. ; Greiner, Georg ; Gueltekin, Sinan ; Heller, Gerwin ; Herkner, Harald ; Hoermann, Gregor ; Kiladjian, Jean-Jacques ; Kolbe, Thomas ; Kornauth, Christoph ; Krauth, Maria-Theresa ; Kralovics, Robert ; Muellauer, Leonhard ; Mueller, Mathias ; Prchal-Murphy, Michaela ; Putz, Eva Maria ; Raffoux, Emmanuel ; Schiefer, Ana-Iris ; Schmetterer, Klaus ; Schneckenleithner, Christine ; Simonitsch-Klupp, Ingrid ; Skrabs, Cathrin ; Sperr, Wolfgang R. ; Staber, Philipp Bernhard ; Strobl, Birgit ; Valent, Peter ; Jaeger, Ulrich ; Gisslinger, Heinz ; Sexl, Veronika

Blood, 2018-08, Vol.132 (7), p.694-706 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

Maude, Shannon L. ; Tasian, Sarah K. ; Vincent, Tiffaney ; Hall, Junior W. ; Sheen, Cecilia ; Roberts, Kathryn G. ; Seif, Alix E. ; Barrett, David M. ; Chen, I-Ming ; Collins, J. Racquel ; Mullighan, Charles G. ; Hunger, Stephen P. ; Harvey, Richard C. ; Willman, Cheryl L. ; Fridman, Jordan S. ; Loh, Mignon L. ; Grupp, Stephan A. ; Teachey, David T.

Blood, 2012-10, Vol.120 (17), p.3510-3518 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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3
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
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African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

Li, Dan ; Zhang, Jing ; Yang, Wenping ; Li, Pan ; Ru, Yi ; Kang, Weifang ; Li, LuLu ; Ran, Yong ; Zheng, Haixue

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101190-101190, Article 101190 [Periódico revisado por pares]

United States: Elsevier Inc

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4
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
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JAK2 inhibitors for myeloproliferative neoplasms: what is next?

Bose, Prithviraj ; Verstovsek, Srdan

Blood, 2017-07, Vol.130 (2), p.115-125 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
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Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway

Tang, Liu-Ya ; Heller, Mary ; Meng, Zhaojing ; Yu, Li-Rong ; Tang, Yi ; Zhou, Ming ; Zhang, Ying E.

The Journal of biological chemistry, 2017-03, Vol.292 (10), p.4302-4312 [Periódico revisado por pares]

United States: Elsevier Inc

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6
CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms
CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms
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CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

Tyner, Jeffrey W. ; Bumm, Thomas G. ; Deininger, Jutta ; Wood, Lisa ; Aichberger, Karl J. ; Loriaux, Marc M. ; Druker, Brian J. ; Burns, Christopher J. ; Fantino, Emmanuelle ; Deininger, Michael W.

Blood, 2010-06, Vol.115 (25), p.5232-5240 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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7
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain
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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain

Tokarski, John S. ; Zupa-Fernandez, Adriana ; Tredup, Jeffrey A. ; Pike, Kristen ; Chang, ChiehYing ; Xie, Dianlin ; Cheng, Lihong ; Pedicord, Donna ; Muckelbauer, Jodi ; Johnson, Stephen R. ; Wu, Sophie ; Edavettal, Suzanne C. ; Hong, Yang ; Witmer, Mark R. ; Elkin, Lisa L. ; Blat, Yuval ; Pitts, William J. ; Weinstein, David S. ; Burke, James R.

The Journal of biological chemistry, 2015-04, Vol.290 (17), p.11061-11074 [Periódico revisado por pares]

United States: Elsevier Inc

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8
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
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JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML

Karjalainen, Riikka ; Pemovska, Tea ; Popa, Mihaela ; Liu, Minxia ; Javarappa, Komal K. ; Majumder, Muntasir M. ; Yadav, Bhagwan ; Tamborero, David ; Tang, Jing ; Bychkov, Dmitrii ; Kontro, Mika ; Parsons, Alun ; Suvela, Minna ; Mayoral Safont, Mireia ; Porkka, Kimmo ; Aittokallio, Tero ; Kallioniemi, Olli ; McCormack, Emmet ; Gjertsen, Bjørn T. ; Wennerberg, Krister ; Knowles, Jonathan ; Heckman, Caroline A.

Blood, 2017-08, Vol.130 (6), p.789-802 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project
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Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project

Loh, Mignon L. ; Zhang, Jinghui ; Harvey, Richard C. ; Roberts, Kathryn ; Payne-Turner, Debbie ; Kang, Huining ; Wu, Gang ; Chen, Xiang ; Becksfort, Jared ; Edmonson, Michael ; Buetow, Kenneth H. ; Carroll, William L. ; Chen, I-Ming ; Wood, Brent ; Borowitz, Michael J. ; Devidas, Meenakshi ; Gerhard, Daniela S. ; Bowman, Paul ; Larsen, Eric ; Winick, Naomi ; Raetz, Elizabeth ; Smith, Malcolm ; Downing, James R. ; Willman, Cheryl L. ; Mullighan, Charles G. ; Hunger, Stephen P.

Blood, 2013-01, Vol.121 (3), p.485-488 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities
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Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities

Losdyck, Elisabeth ; Hornakova, Tekla ; Springuel, Lorraine ; Degryse, Sandrine ; Gielen, Olga ; Cools, Jan ; Constantinescu, Stefan N. ; Flex, Elisabetta ; Tartaglia, Marco ; Renauld, Jean-Christophe ; Knoops, Laurent

The Journal of biological chemistry, 2015-11, Vol.290 (48), p.29022-29034 [Periódico revisado por pares]

United States: Elsevier Inc

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