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The molecular basis of JAK/STAT inhibition by SOCS1
The molecular basis of JAK/STAT inhibition by SOCS1
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The molecular basis of JAK/STAT inhibition by SOCS1

Liau, Nicholas P D ; Laktyushin, Artem ; Lucet, Isabelle S ; Murphy, James M ; Yao, Shenggen ; Whitlock, Eden ; Callaghan, Kimberley ; Nicola, Nicos A ; Kershaw, Nadia J ; Babon, Jeffrey J

Nature communications, 2018-04, Vol.9 (1), p.1558-14, Article 1558 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, Edit ; Tripolt, Sabrina ; Hoelbl-Kovacic, Andrea ; Gisslinger, Bettina ; Bago-Horvath, Zsuzsanna ; Casanova-Hevia, Emilio ; Clappier, Emmanuelle ; Decker, Thomas ; Fajmann, Sabine ; Fux, Daniela A. ; Greiner, Georg ; Gueltekin, Sinan ; Heller, Gerwin ; Herkner, Harald ; Hoermann, Gregor ; Kiladjian, Jean-Jacques ; Kolbe, Thomas ; Kornauth, Christoph ; Krauth, Maria-Theresa ; Kralovics, Robert ; Muellauer, Leonhard ; Mueller, Mathias ; Prchal-Murphy, Michaela ; Putz, Eva Maria ; Raffoux, Emmanuel ; Schiefer, Ana-Iris ; Schmetterer, Klaus ; Schneckenleithner, Christine ; Simonitsch-Klupp, Ingrid ; Skrabs, Cathrin ; Sperr, Wolfgang R. ; Staber, Philipp Bernhard ; Strobl, Birgit ; Valent, Peter ; Jaeger, Ulrich ; Gisslinger, Heinz ; Sexl, Veronika

Blood, 2018-08, Vol.132 (7), p.694-706 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages

Runtsch, Marah C. ; Angiari, Stefano ; Hooftman, Alexander ; Wadhwa, Ridhima ; Zhang, Yanling ; Zheng, Yunan ; Spina, Joseph S. ; Ruzek, Melanie C. ; Argiriadi, Maria A. ; McGettrick, Anne F. ; Mendez, Rui Santalla ; Zotta, Alessia ; Peace, Christian G. ; Walsh, Aoife ; Chirillo, Roberta ; Hams, Emily ; Fallon, Padraic G. ; Jayaraman, Ranjith ; Dua, Kamal ; Brown, Alexandra C. ; Kim, Richard Y. ; Horvat, Jay C. ; Hansbro, Philip M. ; Wang, Chu ; O’Neill, Luke A.J.

Cell metabolism, 2022-03, Vol.34 (3), p.487-501.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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4
A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro
A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro
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A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro

Murakami, Kohei ; Kobayashi, Yasuhiro ; Uehara, Shunsuke ; Suzuki, Takako ; Koide, Masanori ; Yamashita, Teruhito ; Nakamura, Midori ; Takahashi, Naoyuki ; Kato, Hiroyuki ; Udagawa, Nobuyuki ; Nakamura, Yukio Reddy, Sakamuri V.

PloS one, 2017-07, Vol.12 (7), p.e0181126-e0181126 [Periódico revisado por pares]

United States: Public Library of Science

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5
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
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Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Garcia-Diaz, Angel ; Shin, Daniel Sanghoon ; Moreno, Blanca Homet ; Saco, Justin ; Escuin-Ordinas, Helena ; Rodriguez, Gabriel Abril ; Zaretsky, Jesse M. ; Sun, Lu ; Hugo, Willy ; Wang, Xiaoyan ; Parisi, Giulia ; Saus, Cristina Puig ; Torrejon, Davis Y. ; Graeber, Thomas G. ; Comin-Anduix, Begonya ; Hu-Lieskovan, Siwen ; Damoiseaux, Robert ; Lo, Roger S. ; Ribas, Antoni

Cell reports (Cambridge), 2017-05, Vol.19 (6), p.1189-1201 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial
Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial
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Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial

Reich, Kristian ; Kabashima, Kenji ; Peris, Ketty ; Silverberg, Jonathan I ; Eichenfield, Lawrence F ; Bieber, Thomas ; Kaszuba, Aleksandra ; Kolodsick, Jill ; Yang, Fan E ; Gamalo, Margaret ; Brinker, Dennis R ; DeLozier, Amy M ; Janes, Jonathan M ; Nunes, Fabio P ; Thyssen, Jacob P ; Simpson, Eric L

Archives of dermatology (1960), 2020-12, Vol.156 (12), p.1333-1343 [Periódico revisado por pares]

United States: American Medical Association

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7
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
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African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

Li, Dan ; Zhang, Jing ; Yang, Wenping ; Li, Pan ; Ru, Yi ; Kang, Weifang ; Li, LuLu ; Ran, Yong ; Zheng, Haixue

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101190-101190, Article 101190 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients
Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients
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Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

Kim, Hanna ; Brooks, Kristina M. ; Tang, Cheng Cai ; Wakim, Paul ; Blake, Mary ; Brooks, Stephen R. ; Montealegre Sanchez, Gina A. ; de Jesus, Adriana A. ; Huang, Yan ; Tsai, Wanxia Li ; Gadina, Massimo ; Prakash, Apurva ; Janes, Jonathan Marcus ; Zhang, Xin ; Macias, William L. ; Kumar, Parag ; Goldbach‐Mansky, Raphaela

Clinical pharmacology and therapeutics, 2018-08, Vol.104 (2), p.364-373 [Periódico revisado por pares]

United States

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9
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
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Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation

Glassman, Caleb R ; Tsutsumi, Naotaka ; Saxton, Robert A ; Lupardus, Patrick J ; Jude, Kevin M ; Garcia, K Christopher

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6589), p.163-169 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma

Biffi, Giulia ; Oni, Tobiloba E ; Spielman, Benjamin ; Hao, Yuan ; Elyada, Ela ; Park, Youngkyu ; Preall, Jonathan ; Tuveson, David A

Cancer discovery, 2019-02, Vol.9 (2), p.282-301

United States

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