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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
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Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, Edit ; Tripolt, Sabrina ; Hoelbl-Kovacic, Andrea ; Gisslinger, Bettina ; Bago-Horvath, Zsuzsanna ; Casanova-Hevia, Emilio ; Clappier, Emmanuelle ; Decker, Thomas ; Fajmann, Sabine ; Fux, Daniela A. ; Greiner, Georg ; Gueltekin, Sinan ; Heller, Gerwin ; Herkner, Harald ; Hoermann, Gregor ; Kiladjian, Jean-Jacques ; Kolbe, Thomas ; Kornauth, Christoph ; Krauth, Maria-Theresa ; Kralovics, Robert ; Muellauer, Leonhard ; Mueller, Mathias ; Prchal-Murphy, Michaela ; Putz, Eva Maria ; Raffoux, Emmanuel ; Schiefer, Ana-Iris ; Schmetterer, Klaus ; Schneckenleithner, Christine ; Simonitsch-Klupp, Ingrid ; Skrabs, Cathrin ; Sperr, Wolfgang R. ; Staber, Philipp Bernhard ; Strobl, Birgit ; Valent, Peter ; Jaeger, Ulrich ; Gisslinger, Heinz ; Sexl, Veronika

Blood, 2018-08, Vol.132 (7), p.694-706 [Peer Reviewed Journal]

United States: Elsevier Inc

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2
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
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Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance

QUINTAS-CARDAMA, Alfonso ; VERSTOVSEK, Srdan

Clinical cancer research, 2013-04, Vol.19 (8), p.1933-1940 [Peer Reviewed Journal]

Philadelphia, PA: American Association for Cancer Research

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3
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

Maude, Shannon L. ; Tasian, Sarah K. ; Vincent, Tiffaney ; Hall, Junior W. ; Sheen, Cecilia ; Roberts, Kathryn G. ; Seif, Alix E. ; Barrett, David M. ; Chen, I-Ming ; Collins, J. Racquel ; Mullighan, Charles G. ; Hunger, Stephen P. ; Harvey, Richard C. ; Willman, Cheryl L. ; Fridman, Jordan S. ; Loh, Mignon L. ; Grupp, Stephan A. ; Teachey, David T.

Blood, 2012-10, Vol.120 (17), p.3510-3518 [Peer Reviewed Journal]

Washington, DC: Elsevier Inc

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4
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
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Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Lupardus, Patrick J. ; Ultsch, Mark ; Wallweber, Heidi ; Kohli, Pawan Bir ; Johnson, Adam R. ; Eigenbrot, Charles

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8025-8030 [Peer Reviewed Journal]

United States: National Academy of Sciences

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5
JAK mutations in high-risk childhood acute lymphoblastic leukemia
JAK mutations in high-risk childhood acute lymphoblastic leukemia
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JAK mutations in high-risk childhood acute lymphoblastic leukemia

Mullighan, Charles G ; Zhang, Jinghui ; Harvey, Richard C ; Collins-Underwood, J. Racquel ; Schulman, Brenda A ; Phillips, Letha A ; Tasian, Sarah K ; Loh, Mignon L ; Su, Xiaoping ; Liu, Wei ; Devidas, Meenakshi ; Atlas, Susan R ; Chen, I. Ming ; Clifford, Robert J ; Gerhard, Daniela S ; Carroll, William L ; Reaman, Gregory H ; Smith, Malcolm ; Downing, James R ; Hunger, Stephen P ; Willman, Cheryl L

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9414-9418 [Peer Reviewed Journal]

United States: National Academy of Sciences

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6
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
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African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

Li, Dan ; Zhang, Jing ; Yang, Wenping ; Li, Pan ; Ru, Yi ; Kang, Weifang ; Li, LuLu ; Ran, Yong ; Zheng, Haixue

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101190-101190, Article 101190 [Peer Reviewed Journal]

United States: Elsevier Inc

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7
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
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Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation

Glassman, Caleb R ; Tsutsumi, Naotaka ; Saxton, Robert A ; Lupardus, Patrick J ; Jude, Kevin M ; Garcia, K Christopher

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6589), p.163-169 [Peer Reviewed Journal]

United States: The American Association for the Advancement of Science

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8
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma

Biffi, Giulia ; Oni, Tobiloba E ; Spielman, Benjamin ; Hao, Yuan ; Elyada, Ela ; Park, Youngkyu ; Preall, Jonathan ; Tuveson, David A

Cancer discovery, 2019-02, Vol.9 (2), p.282-301

United States

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9
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
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JAK2 inhibitors for myeloproliferative neoplasms: what is next?

Bose, Prithviraj ; Verstovsek, Srdan

Blood, 2017-07, Vol.130 (2), p.115-125 [Peer Reviewed Journal]

United States: Elsevier Inc

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10
Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
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Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway

Tang, Liu-Ya ; Heller, Mary ; Meng, Zhaojing ; Yu, Li-Rong ; Tang, Yi ; Zhou, Ming ; Zhang, Ying E.

The Journal of biological chemistry, 2017-03, Vol.292 (10), p.4302-4312 [Peer Reviewed Journal]

United States: Elsevier Inc

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