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1 |
Material Type: Artigo
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The molecular basis of JAK/STAT inhibition by SOCS1Liau, Nicholas P D ; Laktyushin, Artem ; Lucet, Isabelle S ; Murphy, James M ; Yao, Shenggen ; Whitlock, Eden ; Callaghan, Kimberley ; Nicola, Nicos A ; Kershaw, Nadia J ; Babon, Jeffrey JNature communications, 2018-04, Vol.9 (1), p.1558-14, Article 1558 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapyKOPPIKAR, Priya ; BHAGWAT, Neha ; LEUNG, Laura ; WEINSTEIN, Abby ; MARUBAYASHI, Sachie ; GOEL, Aviva ; GÖNEN, Mithat ; ESTROV, Zeev ; EBERT, Benjamin L ; CHIOSIS, Gabriela ; NIMER, Stephen D ; BERNSTEIN, Bradley E ; KILPIVAARA, Outi ; VERSTOVSEK, Srdan ; LEVINE, Ross L ; MANSHOURI, Taghi ; ADLI, Mazhar ; HRICIK, Todd ; FAN LIU ; SAUNDERS, Lindsay M ; MULLALLY, Ann ; ABDEL-WAHAB, OmarNature (London), 2012-09, Vol.489 (7414), p.155-159 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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3 |
Material Type: Artigo
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JAK inhibition in the treatment of diabetic kidney diseaseBrosius, Frank C. ; Tuttle, Katherine R. ; Kretzler, MatthiasDiabetologia, 2016-08, Vol.59 (8), p.1624-1627 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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4 |
Material Type: Artigo
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The molecular regulation of Janus kinase (JAK) activationBabon, Jeffrey J ; Lucet, Isabelle S ; Murphy, James M ; Nicola, Nicos A ; Varghese, Leila NBiochemical journal, 2014-08, Vol.462 (1), p.1-13 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitroMurakami, Kohei ; Kobayashi, Yasuhiro ; Uehara, Shunsuke ; Suzuki, Takako ; Koide, Masanori ; Yamashita, Teruhito ; Nakamura, Midori ; Takahashi, Naoyuki ; Kato, Hiroyuki ; Udagawa, Nobuyuki ; Nakamura, Yukio Reddy, Sakamuri V.PloS one, 2017-07, Vol.12 (7), p.e0181126-e0181126 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical TrialReich, Kristian ; Kabashima, Kenji ; Peris, Ketty ; Silverberg, Jonathan I ; Eichenfield, Lawrence F ; Bieber, Thomas ; Kaszuba, Aleksandra ; Kolodsick, Jill ; Yang, Fan E ; Gamalo, Margaret ; Brinker, Dennis R ; DeLozier, Amy M ; Janes, Jonathan M ; Nunes, Fabio P ; Thyssen, Jacob P ; Simpson, Eric LArchives of dermatology (1960), 2020-12, Vol.156 (12), p.1333-1343 [Periódico revisado por pares]United States: American Medical AssociationTexto completo disponível |
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Material Type: Artigo
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathwayOllila, Saara ; Domènech-Moreno, Eva ; Laajanen, Kaisa ; Wong, Iris Pl ; Tripathi, Sushil ; Pentinmikko, Nalle ; Gao, Yajing ; Yan, Yan ; Niemelä, Elina H ; Wang, Timothy C ; Viollet, Benoit ; Leone, Gustavo ; Katajisto, Pekka ; Vaahtomeri, Kari ; Mäkelä, Tomi PThe Journal of clinical investigation, 2018-01, Vol.128 (1), p.402-414 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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Material Type: Artigo
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Identification of essential genes for cancer immunotherapyPatel, Shashank J ; Sanjana, Neville E ; Kishton, Rigel J ; Eidizadeh, Arash ; Vodnala, Suman K ; Cam, Maggie ; Gartner, Jared J ; Jia, Li ; Steinberg, Seth M ; Yamamoto, Tori N ; Merchant, Anand S ; Mehta, Gautam U ; Chichura, Anna ; Shalem, Ophir ; Tran, Eric ; Eil, Robert ; Sukumar, Madhusudhanan ; Guijarro, Eva Perez ; Day, Chi-Ping ; Robbins, Paul ; Feldman, Steve ; Merlino, Glenn ; Zhang, Feng ; Restifo, Nicholas PNature (London), 2017-08, Vol.548 (7669), p.537-542 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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9 |
Material Type: Artigo
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Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxiaAlmiron Bonnin, D A ; Havrda, M C ; Lee, M C ; Liu, H ; Zhang, Z ; Nguyen, L N ; Harrington, L X ; Hassanpour, S ; Cheng, C ; Israel, M AOncogene, 2018-02, Vol.37 (8), p.1107-1118 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathwayZhuang, Guanglei ; Wu, Xiumin ; Jiang, Zhaoshi ; Kasman, Ian ; Yao, Jenny ; Guan, Yinghui ; Oeh, Jason ; Modrusan, Zora ; Bais, Carlos ; Sampath, Deepak ; Ferrara, NapoleoneThe EMBO journal, 2012-08, Vol.31 (17), p.3513-3523 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |