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1 |
Material Type: Artigo
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The molecular basis of JAK/STAT inhibition by SOCS1Liau, Nicholas P D ; Laktyushin, Artem ; Lucet, Isabelle S ; Murphy, James M ; Yao, Shenggen ; Whitlock, Eden ; Callaghan, Kimberley ; Nicola, Nicos A ; Kershaw, Nadia J ; Babon, Jeffrey JNature communications, 2018-04, Vol.9 (1), p.1558-14, Article 1558 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibitionLupardus, Patrick J. ; Ultsch, Mark ; Wallweber, Heidi ; Kohli, Pawan Bir ; Johnson, Adam R. ; Eigenbrot, CharlesProceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8025-8030 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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The molecular regulation of Janus kinase (JAK) activationBabon, Jeffrey J ; Lucet, Isabelle S ; Murphy, James M ; Nicola, Nicos A ; Varghese, Leila NBiochemical journal, 2014-08, Vol.462 (1), p.1-13 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitroMurakami, Kohei ; Kobayashi, Yasuhiro ; Uehara, Shunsuke ; Suzuki, Takako ; Koide, Masanori ; Yamashita, Teruhito ; Nakamura, Midori ; Takahashi, Naoyuki ; Kato, Hiroyuki ; Udagawa, Nobuyuki ; Nakamura, Yukio Reddy, Sakamuri V.PloS one, 2017-07, Vol.12 (7), p.e0181126-e0181126 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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JAK mutations in high-risk childhood acute lymphoblastic leukemiaMullighan, Charles G ; Zhang, Jinghui ; Harvey, Richard C ; Collins-Underwood, J. Racquel ; Schulman, Brenda A ; Phillips, Letha A ; Tasian, Sarah K ; Loh, Mignon L ; Su, Xiaoping ; Liu, Wei ; Devidas, Meenakshi ; Atlas, Susan R ; Chen, I. Ming ; Clifford, Robert J ; Gerhard, Daniela S ; Carroll, William L ; Reaman, Gregory H ; Smith, Malcolm ; Downing, James R ; Hunger, Stephen P ; Willman, Cheryl LProceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9414-9418 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signalingLi, Dan ; Zhang, Jing ; Yang, Wenping ; Li, Pan ; Ru, Yi ; Kang, Weifang ; Li, LuLu ; Ran, Yong ; Zheng, HaixueThe Journal of biological chemistry, 2021-11, Vol.297 (5), p.101190-101190, Article 101190 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD PathwayTang, Liu-Ya ; Heller, Mary ; Meng, Zhaojing ; Yu, Li-Rong ; Tang, Yi ; Zhou, Ming ; Zhang, Ying E.The Journal of biological chemistry, 2017-03, Vol.292 (10), p.4302-4312 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathwayZhuang, Guanglei ; Wu, Xiumin ; Jiang, Zhaoshi ; Kasman, Ian ; Yao, Jenny ; Guan, Yinghui ; Oeh, Jason ; Modrusan, Zora ; Bais, Carlos ; Sampath, Deepak ; Ferrara, NapoleoneThe EMBO journal, 2012-08, Vol.31 (17), p.3513-3523 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |
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Material Type: Artigo
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathwayOllila, Saara ; Domènech-Moreno, Eva ; Laajanen, Kaisa ; Wong, Iris Pl ; Tripathi, Sushil ; Pentinmikko, Nalle ; Gao, Yajing ; Yan, Yan ; Niemelä, Elina H ; Wang, Timothy C ; Viollet, Benoit ; Leone, Gustavo ; Katajisto, Pekka ; Vaahtomeri, Kari ; Mäkelä, Tomi PThe Journal of clinical investigation, 2018-01, Vol.128 (1), p.402-414 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
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10 |
Material Type: Artigo
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STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptorWang, Yuxin ; van Boxel-Dezaire, Anette H. H. ; Cheon, HyeonJoo ; Yang, Jinbo ; Stark, George R.Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (42), p.16975-16980 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |