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1
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
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Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

Murtaza, Muhammed ; Dawson, Sarah-Jane ; Tsui, Dana W Y ; Gale, Davina ; Forshew, Tim ; Piskorz, Anna M ; Parkinson, Christine ; Chin, Suet-Feung ; Kingsbury, Zoya ; Wong, Alvin S C ; Marass, Francesco ; Humphray, Sean ; Hadfield, James ; Bentley, David ; Chin, Tan Min ; Brenton, James D ; Caldas, Carlos ; Rosenfeld, Nitzan

Nature (London), 2013-05, Vol.497 (7447), p.108-112 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Genomic Approaches to Understanding Response and Resistance to Immunotherapy
Genomic Approaches to Understanding Response and Resistance to Immunotherapy
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Genomic Approaches to Understanding Response and Resistance to Immunotherapy

Braun, David A ; Burke, Kelly P ; Van Allen, Eliezer M

Clinical cancer research, 2016-12, Vol.22 (23), p.5642-5650 [Periódico revisado por pares]

United States

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3
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
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Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Hata, Aaron N ; Niederst, Matthew J ; Archibald, Hannah L ; Gomez-Caraballo, Maria ; Siddiqui, Faria M ; Mulvey, Hillary E ; Maruvka, Yosef E ; Ji, Fei ; Bhang, Hyo-eun C ; Krishnamurthy Radhakrishna, Viveksagar ; Siravegna, Giulia ; Hu, Haichuan ; Raoof, Sana ; Lockerman, Elizabeth ; Kalsy, Anuj ; Lee, Dana ; Keating, Celina L ; Ruddy, David A ; Damon, Leah J ; Crystal, Adam S ; Costa, Carlotta ; Piotrowska, Zofia ; Bardelli, Alberto ; Iafrate, Anthony J ; Sadreyev, Ruslan I ; Stegmeier, Frank ; Getz, Gad ; Sequist, Lecia V ; Faber, Anthony C ; Engelman, Jeffrey A

Nature medicine, 2016-03, Vol.22 (3), p.262-269 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells
PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells
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PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

Kahn, Josephine D. ; Miller, Peter G. ; Silver, Alexander J. ; Sellar, Rob S. ; Bhatt, Shruti ; Gibson, Christopher ; McConkey, Marie ; Adams, Dylan ; Mar, Brenton ; Mertins, Philipp ; Fereshetian, Shaunt ; Krug, Karsten ; Zhu, Haoling ; Letai, Anthony ; Carr, Steven A. ; Doench, John ; Jaiswal, Siddhartha ; Ebert, Benjamin L.

Blood, 2018-09, Vol.132 (11), p.1095-1105 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

Shu, Shaokun ; Lin, Charles Y ; He, Housheng Hansen ; Witwicki, Robert M ; Tabassum, Doris P ; Roberts, Justin M ; Janiszewska, Michalina ; Huh, Sung Jin ; Liang, Yi ; Ryan, Jeremy ; Doherty, Ernest ; Mohammed, Hisham ; Guo, Hao ; Stover, Daniel G ; Ekram, Muhammad B ; Brown, Jonathan ; D'Santos, Clive ; Krop, Ian E ; Dillon, Deborah ; McKeown, Michael ; Ott, Christopher ; Qi, Jun ; Ni, Min ; Rao, Prakash K ; Duarte, Melissa ; Wu, Shwu-Yuan ; Chiang, Cheng-Ming ; Anders, Lars ; Young, Richard A ; Winer, Eric ; Letai, Antony ; Barry, William T ; Carroll, Jason S ; Long, Henry ; Brown, Myles ; Liu, X Shirley ; Meyer, Clifford A ; Bradner, James E ; Polyak, Kornelia

Nature (London), 2016-01, Vol.529 (7586), p.413-417 [Periódico revisado por pares]

England: Nature Publishing Group

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6
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
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The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

DIAZ, Luis A ; WILLIAMS, Richard T ; KINZLER, Kenneth W ; OLINER, Kelly S ; VOGELSTEIN, Bert ; JIAN WU ; KINDE, Isaac ; HECHT, J. Randolph ; BERLIN, Jordan ; ALLEN, Benjamin ; BOZIC, Ivana ; REITER, Johannes G ; NOWAK, Martin A

Nature (London), 2012-06, Vol.486 (7404), p.537-540 [Periódico revisado por pares]

London: Nature Publishing Group

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7
Replication fork stability confers chemoresistance in BRCA-deficient cells
Replication fork stability confers chemoresistance in BRCA-deficient cells
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Replication fork stability confers chemoresistance in BRCA-deficient cells

Ray Chaudhuri, Arnab ; Callen, Elsa ; Ding, Xia ; Gogola, Ewa ; Duarte, Alexandra A ; Lee, Ji-Eun ; Wong, Nancy ; Lafarga, Vanessa ; Calvo, Jennifer A ; Panzarino, Nicholas J ; John, Sam ; Day, Amanda ; Crespo, Anna Vidal ; Shen, Binghui ; Starnes, Linda M ; de Ruiter, Julian R ; Daniel, Jeremy A ; Konstantinopoulos, Panagiotis A ; Cortez, David ; Cantor, Sharon B ; Fernandez-Capetillo, Oscar ; Ge, Kai ; Jonkers, Jos ; Rottenberg, Sven ; Sharan, Shyam K ; Nussenzweig, André

Nature (London), 2016-07, Vol.535 (7612), p.382-387 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Targeting the PI3K/AKT/mTOR Pathway in Hormone-Positive Breast Cancer
Targeting the PI3K/AKT/mTOR Pathway in Hormone-Positive Breast Cancer
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Targeting the PI3K/AKT/mTOR Pathway in Hormone-Positive Breast Cancer

Nunnery, Sara E. ; Mayer, Ingrid A.

Drugs (New York, N.Y.), 2020-11, Vol.80 (16), p.1685-1697 [Periódico revisado por pares]

Cham: Springer International Publishing

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9
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
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Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

Shaffer, Sydney M ; Dunagin, Margaret C ; Torborg, Stefan R ; Torre, Eduardo A ; Emert, Benjamin ; Krepler, Clemens ; Beqiri, Marilda ; Sproesser, Katrin ; Brafford, Patricia A ; Xiao, Min ; Eggan, Elliott ; Anastopoulos, Ioannis N ; Vargas-Garcia, Cesar A ; Singh, Abhyudai ; Nathanson, Katherine L ; Herlyn, Meenhard ; Raj, Arjun

Nature (London), 2017-06, Vol.546 (7658), p.431-435 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
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Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial

Cortes, Jorge E. ; Kim, Dong-Wook ; Pinilla-Ibarz, Javier ; le Coutre, Philipp D. ; Paquette, Ronald ; Chuah, Charles ; Nicolini, Franck E. ; Apperley, Jane F. ; Khoury, H. Jean ; Talpaz, Moshe ; DeAngelo, Daniel J. ; Abruzzese, Elisabetta ; Rea, Delphine ; Baccarani, Michele ; Müller, Martin C. ; Gambacorti-Passerini, Carlo ; Lustgarten, Stephanie ; Rivera, Victor M. ; Haluska, Frank G. ; Guilhot, François ; Deininger, Michael W. ; Hochhaus, Andreas ; Hughes, Timothy P. ; Shah, Neil P. ; Kantarjian, Hagop M.

Blood, 2018-07, Vol.132 (4), p.393-404 [Periódico revisado por pares]

United States: Elsevier Inc

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