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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Shi, Hubing ; Sazegar, Hooman ; Nazarian, Ramin ; Chodon, Thinle ; Lee, Hane ; Sosman, Jeffrey A ; Lo, Roger S ; Koya, Richard C ; Lee, Mi-Kyung ; Attar, Narsis ; Kong, Xiangju ; Nelson, Stanley F ; Ribas, Antoni ; Chen, Zugen ; McArthur, Grant ; Wang, Qi

Nature (London), 2010-12, Vol.468 (7326), p.973-977 [Periódico revisado por pares]

London: Nature Publishing Group

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2
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Emery, Caroline M ; Hieronymus, Haley ; Zhao, Jean J ; Boehm, Jesse S ; Golub, Todd ; Yang, Xiaoping ; Root, David E ; Roberts, Thomas M ; Hahn, William C ; Hill, David E ; Wilson, Christopher J ; Weber, Barbara L ; Garraway, Levi A ; Johnson, Laura A ; Kim, Sungjoon ; Harris, Jennifer L ; Kim, So Young ; Vidal, Marc ; Finan, Peter M ; Myer, Vic E ; Sellers, William R ; Barretina, Jordi ; Alkan, Ozan ; Thomas, Sapana R ; Wardwell, Leslie ; Cogdill, Alexandria P ; Dummer, Reinhard ; Schlegel, Robert ; Stransky, Nicolas ; Flaherty, Keith T ; Wargo, Jennifer A ; Murray, Ryan R ; Johannessen, Cory M ; Salehi-Ashtiani, Kourosh ; Caponigro, Giordano

Nature (London), 2010-12, Vol.468 (7326), p.968-972 [Periódico revisado por pares]

London: Nature Publishing Group

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3
Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban
Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban
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Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban

Mueck, Wolfgang ; Stampfuss, Jan ; Kubitza, Dagmar ; Becka, Michael

Clinical pharmacokinetics, 2014-01, Vol.53 (1), p.1-16 [Periódico revisado por pares]

Cham: Springer International Publishing

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4
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

WILSON, Timothy R ; FRIDLYAND, Jane ; RIBAS, Antoni ; JIANG LI ; MOFFAT, John ; SUTHERLIN, Daniel P ; KOEPPEN, Hartmut ; MERCHANT, Mark ; NEVE, Richard ; SETTLEMAN, Jeff ; YIBING YAN ; PENUEL, Elicia ; BURTON, Luciana ; CHAN, Emily ; JING PENG ; EVA LIN ; YULEI WANG ; SOSMAN, Jeff

Nature (London), 2012-07, Vol.487 (7408), p.505-509 [Periódico revisado por pares]

London: Nature Publishing Group

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5
Suppression of inflammation by a synthetic histone mimic
Suppression of inflammation by a synthetic histone mimic
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Suppression of inflammation by a synthetic histone mimic

NICODEME, Edwige ; JEFFREY, Kate L ; WHITE, Julia ; KIRILOVSKY, Jorge ; RICE, Charles M ; LORA, Jose M ; PRINJHA, Rab K ; LEE, Kevin ; TARAKHOVSKY, Alexander ; SCHAEFER, Uwe ; BEINKE, Soren ; DEWELL, Scott ; CHUNG, Chun-Wa ; CHANDWANI, Rohit ; MARAZZI, Ivan ; WILSON, Paul ; COSTE, Hervé

Nature (London), 2010-11, Vol.468 (7327), p.1119-1123 [Periódico revisado por pares]

London: Nature Publishing Group

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6
Systematic identification of genomic markers of drug sensitivity in cancer cells
Systematic identification of genomic markers of drug sensitivity in cancer cells
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Systematic identification of genomic markers of drug sensitivity in cancer cells

GARNETT, Mathew J ; EDELMAN, Elena J ; QINGSONG LIU ; IORIO, Francesco ; SURDEZ, Didier ; LI CHEN ; MILANO, Randy J ; BIGNELL, Graham R ; TAM, Ah T ; DAVIES, Helen ; STEVENSON, Jesse A ; BARTHORPE, Syd ; HEIDORN, Sonja J ; LUTZ, Stephen R ; KOGERA, Fiona ; LAWRENCE, Karl ; MCLAREN-DOUGLAS, Anne ; MITROPOULOS, Xeni ; MIRONENKO, Tatiana ; THI, Helen ; RICHARDSON, Laura ; WENJUN ZHOU ; JEWITT, Frances ; GREENMAN, Chris D ; TINGHU ZHANG ; O'BRIEN, Patrick ; BOISVERT, Jessica L ; PRICE, Stacey ; HUR, Wooyoung ; WANJUAN YANG ; XIANMING DENG ; BUTLER, Adam ; HWAN GEUN CHOI ; JAE WON CHANG ; DASTUR, Anahita ; BASELGA, Jose ; STAMENKOVIC, Ivan ; ENGELMAN, Jeffrey A ; SHARMA, Sreenath V ; DELATTRE, Olivier ; SAEZ-RODRIGUEZ, Julio ; GRAY, Nathanael S ; SETTLEMAN, Jeffrey ; ANDREW FUTREAL, P ; HABER, Daniel A ; KING WAI LAU ; STRATTON, Michael R ; RAMASWAMY, Sridhar ; MCDERMOTT, Ultan ; BENES, Cyril H ; GRENINGER, Patricia ; RICHARD THOMPSON, I ; XI LUO ; SOARES, Jorge

Nature (London), 2012-03, Vol.483 (7391), p.570-575 [Periódico revisado por pares]

London: Nature Publishing Group

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7
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

PRAHALLAD, Anirudh ; CHONG SUN ; SIDONG HUANG ; DI NICOLANTONIO, Federica ; SALAZAR, Ramon ; ZECCHIN, Davide ; BEIJERSBERGEN, Roderick L ; BARDELLI, Alberto ; BERNARDS, René

Nature (London), 2012-01, Vol.483 (7387), p.100-103 [Periódico revisado por pares]

London: Nature Publishing Group

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8
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

STRAUSSMAN, Ravid ; MORIKAWA, Teppei ; COOPER, Zachary A ; CHAPMAN, Paul B ; SOLIT, David B ; RIBAS, Antoni ; LO, Roger S ; FLAHERTY, Keith T ; OGINO, Shuji ; WARGO, Jennifer A ; GOLUB, Todd R ; SHEE, Kevin ; BARZILY-ROKNI, Michal ; RONG QIAN, Zhi ; JINYAN DU ; DAVIS, Ashli ; MONGARE, Margaret M ; GOULD, Joshua ; FREDERICK, Dennie T

Nature (London), 2012-07, Vol.487 (7408), p.500-504 [Periódico revisado por pares]

London: Nature Publishing Group

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9
Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients
Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients
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Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients

Ude, Christian ; Schubert-Zsilavecz, Manfred ; Wurglics, Mario

Clinical pharmacokinetics, 2013-09, Vol.52 (9), p.727-749 [Periódico revisado por pares]

Cham: Springer International Publishing

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10
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
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mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Li, Nanxin ; Lee, Boyoung ; Liu, Rong-Jian ; Banasr, Mounira ; Dwyer, Jason M. ; Iwata, Masaaki ; Li, Xiao-Yuan ; Aghajanian, George ; Duman, Ronald S.

Science (American Association for the Advancement of Science), 2010-08, Vol.329 (5994), p.959-964 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

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