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1
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
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Artigo
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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Emery, Caroline M ; Hieronymus, Haley ; Zhao, Jean J ; Boehm, Jesse S ; Golub, Todd ; Yang, Xiaoping ; Root, David E ; Roberts, Thomas M ; Hahn, William C ; Hill, David E ; Wilson, Christopher J ; Weber, Barbara L ; Garraway, Levi A ; Johnson, Laura A ; Kim, Sungjoon ; Harris, Jennifer L ; Kim, So Young ; Vidal, Marc ; Finan, Peter M ; Myer, Vic E ; Sellers, William R ; Barretina, Jordi ; Alkan, Ozan ; Thomas, Sapana R ; Wardwell, Leslie ; Cogdill, Alexandria P ; Dummer, Reinhard ; Schlegel, Robert ; Stransky, Nicolas ; Flaherty, Keith T ; Wargo, Jennifer A ; Murray, Ryan R ; Johannessen, Cory M ; Salehi-Ashtiani, Kourosh ; Caponigro, Giordano

Nature (London), 2010-12, Vol.468 (7326), p.968-972 [Periódico revisado por pares]

London: Nature Publishing Group

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2
Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates
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Artigo
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Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates

Zhang, Xiao-Xiang ; Eden, Henry S. ; Chen, Xiaoyuan

Journal of controlled release, 2012-04, Vol.159 (1), p.2-13 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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3
Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
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Artigo
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Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

DE WILDE, Adriaan H ; JOCHMANS, Dirk ; POSTHUMA, Clara C ; ZEVENHOVEN-DOBBE, Jessika C ; VAN NIEUWKOOP, Stefan ; BESTEBROER, Theo M ; VAN DEN HOOGEN, Bernadette G ; NEYTS, Johan ; SNIJDER, Eric J

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4875-4884 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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4
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
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Artigo
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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

WILSON, Timothy R ; FRIDLYAND, Jane ; RIBAS, Antoni ; JIANG LI ; MOFFAT, John ; SUTHERLIN, Daniel P ; KOEPPEN, Hartmut ; MERCHANT, Mark ; NEVE, Richard ; SETTLEMAN, Jeff ; YIBING YAN ; PENUEL, Elicia ; BURTON, Luciana ; CHAN, Emily ; JING PENG ; EVA LIN ; YULEI WANG ; SOSMAN, Jeff

Nature (London), 2012-07, Vol.487 (7408), p.505-509 [Periódico revisado por pares]

London: Nature Publishing Group

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5
Hydrogels for biomedical applications
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Artigo
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Hydrogels for biomedical applications

Hoffman, Allan S.

Advanced drug delivery reviews, 2012-12, Vol.64, p.18-23 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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6
Alginates as a useful natural polymer for microencapsulation and therapeutic applications
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Artigo
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Alginates as a useful natural polymer for microencapsulation and therapeutic applications

Goh, Cheong Hian ; Heng, Paul Wan Sia ; Chan, Lai Wah

Carbohydrate polymers, 2012-01, Vol.88 (1), p.1-12 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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7
Systematic identification of genomic markers of drug sensitivity in cancer cells
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Systematic identification of genomic markers of drug sensitivity in cancer cells

GARNETT, Mathew J ; EDELMAN, Elena J ; QINGSONG LIU ; IORIO, Francesco ; SURDEZ, Didier ; LI CHEN ; MILANO, Randy J ; BIGNELL, Graham R ; TAM, Ah T ; DAVIES, Helen ; STEVENSON, Jesse A ; BARTHORPE, Syd ; HEIDORN, Sonja J ; LUTZ, Stephen R ; KOGERA, Fiona ; LAWRENCE, Karl ; MCLAREN-DOUGLAS, Anne ; MITROPOULOS, Xeni ; MIRONENKO, Tatiana ; THI, Helen ; RICHARDSON, Laura ; WENJUN ZHOU ; JEWITT, Frances ; GREENMAN, Chris D ; TINGHU ZHANG ; O'BRIEN, Patrick ; BOISVERT, Jessica L ; PRICE, Stacey ; HUR, Wooyoung ; WANJUAN YANG ; XIANMING DENG ; BUTLER, Adam ; HWAN GEUN CHOI ; JAE WON CHANG ; DASTUR, Anahita ; BASELGA, Jose ; STAMENKOVIC, Ivan ; ENGELMAN, Jeffrey A ; SHARMA, Sreenath V ; DELATTRE, Olivier ; SAEZ-RODRIGUEZ, Julio ; GRAY, Nathanael S ; SETTLEMAN, Jeffrey ; ANDREW FUTREAL, P ; HABER, Daniel A ; KING WAI LAU ; STRATTON, Michael R ; RAMASWAMY, Sridhar ; MCDERMOTT, Ultan ; BENES, Cyril H ; GRENINGER, Patricia ; RICHARD THOMPSON, I ; XI LUO ; SOARES, Jorge

Nature (London), 2012-03, Vol.483 (7391), p.570-575 [Periódico revisado por pares]

London: Nature Publishing Group

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8
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
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Artigo
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Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

MURAI, Junko ; HUANG, Shar-Yin N ; BRATA DAS, Benu ; RENAUD, Amelie ; YIPING ZHANG ; DOROSHOW, James H ; JIUPING JI ; TAKEDA, Shunichi ; POMMIER, Yves

Cancer research (Chicago, Ill.), 2012-11, Vol.72 (21), p.5588-5599 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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9
Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
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Artigo
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Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection

DYALL, Julie ; COLEMAN, Christopher M ; JOHANSEN, Lisa M ; LEAR-ROONEY, Calli M ; GLASS, Pamela J ; HENSLEY, Lisa E ; FRIEMAN, Matthew B ; HART, Brit J ; VENKATARAMAN, Thiagarajan ; HOLBROOK, Michael R ; KINDRACHUK, Jason ; JOHNSON, Reed F ; OLINGER, Gene G ; JAHRLING, Peter B ; LAIDLAW, Monique

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4885-4893 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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10
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
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mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Li, Nanxin ; Lee, Boyoung ; Liu, Rong-Jian ; Banasr, Mounira ; Dwyer, Jason M. ; Iwata, Masaaki ; Li, Xiao-Yuan ; Aghajanian, George ; Duman, Ronald S.

Science (American Association for the Advancement of Science), 2010-08, Vol.329 (5994), p.959-964 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

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