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Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation
Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation
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Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation

Lopes, Marlene A ; Abrahim-Vieira, Bárbara ; Oliveira, Claudia ; Fonte, Pedro ; Souza, Alessandra M T ; Lira, Tammy ; Sequeira, Joana A D ; Rodrigues, Carlos R ; Cabral, Lúcio M ; Sarmento, Bruno ; Seiça, Raquel ; Veiga, Francisco ; Ribeiro, António J

International journal of nanomedicine, 2015-09, Vol.10 (default), p.5865-5880 [Periódico revisado por pares]

New Zealand: Dove Medical Press

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2
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
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Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design

Butler, Christopher R ; Brodney, Michael A ; Beck, Elizabeth M ; Barreiro, Gabriela ; Nolan, Charles E ; Pan, Feng ; Vajdos, Felix ; Parris, Kevin ; Varghese, Alison H ; Helal, Christopher J ; Lira, Ricardo ; Doran, Shawn D ; Riddell, David R ; Buzon, Leanne M ; Dutra, Jason K ; Martinez-Alsina, Luis A ; Ogilvie, Kevin ; Murray, John C ; Young, Joseph M ; Atchison, Kevin ; Robshaw, Ashley ; Gonzales, Cathleen ; Wang, Jinlong ; Zhang, Yong ; O’Neill, Brian T

Journal of medicinal chemistry, 2015-03, Vol.58 (6), p.2678-2702 [Periódico revisado por pares]

United States: American Chemical Society

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3
5-HT2 receptor mechanisms of the dorsal periaqueductal gray in the conditioned and unconditioned fear in rats
5-HT2 receptor mechanisms of the dorsal periaqueductal gray in the conditioned and unconditioned fear in rats
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5-HT2 receptor mechanisms of the dorsal periaqueductal gray in the conditioned and unconditioned fear in rats

CHRYSTINE OLIVEIRA, Luciana ; BROIZ, Ana Carolina ; EDUARDO DE MACEDO, Carlos ; LANDEIRA-FERNANDEZ, J ; LIRA BRANDAO, Marcus

Psychopharmacologia, 2007-04, Vol.191 (2), p.253-262 [Periódico revisado por pares]

Berlin: Springer

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4
Atrial stretch increases the gastric tonus of anesthetized rats
Atrial stretch increases the gastric tonus of anesthetized rats
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Atrial stretch increases the gastric tonus of anesthetized rats

Palheta, R.C. ; Rola, F.H. ; Lira, G.H.S. ; Gomes, D.A. ; Carvalho, F.M. ; Elias, L.L.K. ; Antunes-Rodrigues, J. ; Oliveira, R.B. ; Santos, A.A.

Life sciences (1973), 2010-03, Vol.86 (11), p.441-447 [Periódico revisado por pares]

Netherlands: Elsevier Inc

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5
Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives
Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives
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Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives

Luis, José A. S. ; Aquino, Thiago M. De ; Lira, Bruno F. ; Filho, Petrônio F. A. ; Scotti, Marcus T. ; Scotti, Luciana ; Moura, Ricardo O. De ; Junior, Francisco J. B. Mendonça

Acta pharmaceutica (Zagreb, Croatia), 2014-06, Vol.64 (2), p.233-245 [Periódico revisado por pares]

Croatia: De Gruyter Open

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6
The blockade of AMPA-kainate and NMDA receptors in the dorsal periaqueductal gray reduces the effects of diazepam withdrawal in rats
The blockade of AMPA-kainate and NMDA receptors in the dorsal periaqueductal gray reduces the effects of diazepam withdrawal in rats
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The blockade of AMPA-kainate and NMDA receptors in the dorsal periaqueductal gray reduces the effects of diazepam withdrawal in rats

Souza-Pinto, Luiz F.S. ; Castilho, Vanessa M. ; Brandão, Marcus Lira ; Nobre, Manoel Jorge

Pharmacology, biochemistry and behavior, 2007-06, Vol.87 (2), p.250-257 [Periódico revisado por pares]

New York, NY: Elsevier Inc

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7
Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: effects of muscimol and midazolam
Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: effects of muscimol and midazolam
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Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: effects of muscimol and midazolam

Nobre, Manoel Jorge ; Brandão, Marcus Lira

European neuropsychopharmacology, 2004, Vol.14 (1), p.45-52 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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8
Pharmacological dissociation of moderate and high contextual fear as assessed by freezing behavior and fear-potentiated startle
Pharmacological dissociation of moderate and high contextual fear as assessed by freezing behavior and fear-potentiated startle
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Pharmacological dissociation of moderate and high contextual fear as assessed by freezing behavior and fear-potentiated startle

Santos, Julia Maria ; Gárgaro, Ana Carolina ; Oliveira, Amanda Ribeiro ; Masson, Sueli ; Brandão, Marcus Lira

European neuropsychopharmacology, 2005-03, Vol.15 (2), p.239-246 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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9
Antinociception induced by stimulation of ventrolateral periaqueductal gray at the freezing threshold is regulated by opioid and 5-HT2A receptors as assessed by the tail-flick and formalin tests
Antinociception induced by stimulation of ventrolateral periaqueductal gray at the freezing threshold is regulated by opioid and 5-HT2A receptors as assessed by the tail-flick and formalin tests
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Antinociception induced by stimulation of ventrolateral periaqueductal gray at the freezing threshold is regulated by opioid and 5-HT2A receptors as assessed by the tail-flick and formalin tests

ZANOTO DE LUCA, Maria Cecilia ; LIRA BRANDAO, Marcus ; MOTTA, Vitor Augusto ; LANDEIRA-FEMANDEZ, J

Pharmacology, biochemistry and behavior, 2003-05, Vol.75 (2), p.459-466 [Periódico revisado por pares]

New York, NY: Elsevier Science

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10
Blockade of μ- and activation of κ-opioid receptors in the dorsal periaqueductal gray matter produce defensive behavior in rats tested in the elevated plus-maze
Blockade of μ- and activation of κ-opioid receptors in the dorsal periaqueductal gray matter produce defensive behavior in rats tested in the elevated plus-maze
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Blockade of μ- and activation of κ-opioid receptors in the dorsal periaqueductal gray matter produce defensive behavior in rats tested in the elevated plus-maze

Nobre, Manoel Jorge ; Ribeiro dos Santos, Nelson ; Aguiar, Maria Socorro ; Brandão, Marcus Lira

European journal of pharmacology, 2000-09, Vol.404 (1), p.145-151 [Periódico revisado por pares]

Amsterdam: Elsevier B.V

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