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Material Type: Artigo
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A mutant telomerase defective in nuclear‐cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunctionKovalenko, Olga A. ; Caron, Matthieu J. ; Ulema, Perihan ; Medrano, Carolina ; Thomas, Andrew P. ; Kimura, Masayuki ; Bonini, Marcelo G. ; Herbig, Utz ; Santos, Janine H.Aging cell, 2010-04, Vol.9 (2), p.203-219 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high‐fat dietLeontieva, Olga V. ; Paszkiewicz, Geraldine M. ; Blagosklonny, Mikhail V.Aging cell, 2014-08, Vol.13 (4), p.616-622 [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κB activationMoiseeva, Olga ; Deschênes‐Simard, Xavier ; St‐Germain, Emmanuelle ; Igelmann, Sebastian ; Huot, Geneviève ; Cadar, Alexandra E. ; Bourdeau, Véronique ; Pollak, Michael N. ; Ferbeyre, GerardoAging cell, 2013-06, Vol.12 (3), p.489-498 [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Metformin has heterogeneous effects on model organism lifespans and is beneficial when started at an early age in Caenorhabditis elegans: A systematic review and meta‐analysisParish, Austin J. ; Swindell, William R.Aging cell, 2022-12, Vol.21 (12), p.e13733-n/a [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Depletion of DNA damage binding protein 2 sensitizes triple‐negative breast cancer cells to poly ADP‐ribose polymerase inhibition by destabilizing Rad51Zhao, Lin ; Si, Cheng‐Shuai ; Yu, Yue ; Lu, Jian‐Wei ; Zhuang, YanCancer science, 2019-11, Vol.110 (11), p.3543-3552 [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Targeting the ubiquitin‐proteasome system for cancer therapyYang, Yili ; Kitagaki, Jirouta ; Wang, Honghe ; Hou, De‐Xing ; Perantoni, Alan O.Cancer science, 2009-01, Vol.100 (1), p.24-28 [Periódico revisado por pares]Melbourne, Australia: Blackwell Publishing AsiaTexto completo disponível |
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Material Type: Artigo
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Inflammation and cancer: Role of nuclear factor‐kappaB activationMaeda, Shin ; Omata, MasaoCancer science, 2008-05, Vol.99 (5), p.836-842 [Periódico revisado por pares]Melbourne, Australia: Blackwell Publishing AsiaTexto completo disponível |
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Material Type: Artigo
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Intelligent high‐throughput intervention testing platform in DaphniaCho, Yongmin ; Jonas‐Closs, Rachael A. ; Yampolsky, Lev Y. ; Kirschner, Marc W. ; Peshkin, LeonidAging cell, 2022-03, Vol.21 (3), p.e13571-n/a [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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At the crossroads of longevity and metabolism: the metabolic syndrome and lifespan determinant pathwaysFadini, Gian Paolo ; Ceolotto, Giulio ; Pagnin, Elisa ; de Kreutzenberg, Saula ; Avogaro, AngeloAging cell, 2011-02, Vol.10 (1), p.10-17 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Functional implications of tetraspanin proteins in cancer biologyLazo, Pedro A.Cancer science, 2007-11, Vol.98 (11), p.1666-1677 [Periódico revisado por pares]Melbourne, Australia: Blackwell Publishing AsiaTexto completo disponível |