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Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression
Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression
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Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression

Witkin, J M ; Mitchell, S N ; Wafford, K A ; Carter, G ; Gilmour, G ; Li, J ; Eastwood, B J ; Overshiner, C ; Li, X ; Rorick-Kehn, L ; Rasmussen, K ; Anderson, W H ; Nikolayev, A ; Tolstikov, V V ; Kuo, M-S ; Catlow, J T ; Li, R ; Smith, S C ; Mitch, C H ; Ornstein, P L ; Swanson, S ; Monn, J A

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.68-86 [Periódico revisado por pares]

United States

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2
A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP
A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP
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A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP

Lauri, Sari E ; Bortolotto, Zuner A ; Bleakman, David ; Ornstein, Paul L ; Lodge, David ; Isaac, John T.R ; Collingridge, Graham L

Neuron (Cambridge, Mass.), 2001-11, Vol.32 (4), p.697-709 [Periódico revisado por pares]

United States: Elsevier Inc

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3
LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors
LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors
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LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

Kingston, A.E ; Ornstein, P.L ; Wright, R.A ; Johnson, B.G ; Mayne, N.G ; Burnett, J.P ; Belagaje, R ; Wu, S ; Schoepp, D.D

Neuropharmacology, 1998, Vol.37 (1), p.1-12 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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4
Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects
Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects
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Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects

Witkin, J M ; Monn, J A ; Li, J ; Johnson, B ; McKinzie, D L ; Wang, X-S ; Heinz, B A ; Li, R ; Ornstein, P L ; Smith, S C ; Mitch, C H ; Calligaro, D O ; Swanson, S ; Allen, D ; Phillips, K ; Gilmour, G

Pharmacology, biochemistry and behavior, 2017-04, Vol.155, p.43-55 [Periódico revisado por pares]

United States

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5
Kainate receptors are involved in synaptic plasticity
Kainate receptors are involved in synaptic plasticity
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Kainate receptors are involved in synaptic plasticity

Collingridge, Graham L ; Bortolotto, Zuner A ; Clarke, Vernon R. J ; Delany, Caroline M ; Parry, Michael C ; Smolders, Ilse ; Vignes, Michel ; Ho, Ken H ; Miu, Peter ; Brinton, Bradford T ; Fantaske, Robert ; Ogden, Ann ; Gates, Mary ; Ornstein, Paul L ; Lodge, David ; Bleakman, David

Nature (London), 1999-11, Vol.402 (6759), p.297-301 [Periódico revisado por pares]

London: Nature Publishing

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6
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity
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The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity

Fitzjohn, S.M ; Bortolotto, Z.A ; Palmer, M.J ; Doherty, A.J ; Ornstein, P.L ; Schoepp, D.D ; Kingston, A.E ; Lodge, D ; Collingridge, G.L

Neuropharmacology, 1998-12, Vol.37 (12), p.1445-1458 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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7
A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus
A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus
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A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus

Lauri, Sari E ; Bortolotto, Zuner A ; Nistico, Robert ; Bleakman, David ; Ornstein, Paul L ; Lodge, David ; Isaac, John T R ; Collingridge, Graham L

Neuron (Cambridge, Mass.), 2003-07, Vol.39 (2), p.327-341 [Periódico revisado por pares]

United States: Elsevier Limited

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8
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat
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Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat

Simmons, Rosa Maria A. ; Li, Dominic L. ; Hoo, Ken H. ; Deverill, Michelle ; Ornstein, Paul L. ; Iyengar, Smriti

Neuropharmacology, 1998, Vol.37 (1), p.25-36 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Transmembrane AMPA Receptor Regulatory Proteins and Cornichon-2 Allosterically Regulate AMPA Receptor Antagonists and Potentiators
Transmembrane AMPA Receptor Regulatory Proteins and Cornichon-2 Allosterically Regulate AMPA Receptor Antagonists and Potentiators
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Transmembrane AMPA Receptor Regulatory Proteins and Cornichon-2 Allosterically Regulate AMPA Receptor Antagonists and Potentiators

Schober, Douglas A. ; Gill, Martin B. ; Yu, Hong ; Gernert, Douglas L. ; Jeffries, Matthew W. ; Ornstein, Paul L. ; Kato, Akihiko S. ; Felder, Christian C. ; Bredt, David S.

The Journal of biological chemistry, 2011-04, Vol.286 (15), p.13134-13142 [Periódico revisado por pares]

United States: Elsevier Inc

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10
[ 3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells
[ 3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells
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[ 3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells

Johnson, Bryan G ; Wright, Rebecca A ; Arnold, M.Brian ; Wheeler, William J ; Ornstein, Paul L ; Schoepp, Darryle D

Neuropharmacology, 1999-10, Vol.38 (10), p.1519-1529 [Periódico revisado por pares]

England: Elsevier Ltd

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