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Material Type: Artigo
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Allosteric conformational change of a cyclic nucleotide-gated ion channel revealed by DEER spectroscopyEvans, Eric G. B. ; Morgan, Jacob L. W. ; DiMaio, Frank ; Zagotta, William N. ; Stoll, StefanProceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (20), p.10839-10847 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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A second S4 movement opens hyperpolarization-activated HCN channelsWu, Xiaoan ; Ramentol, Rosamary ; Perez, Marta E ; Noskov, Sergei Yu ; Larsson, H PeterProceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (37) [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Detection of ultra-rare mutations by next-generation sequencingSchmitt, Michael W ; Kennedy, Scott R ; Salk, Jesse J ; Fox, Edward J ; Hiatt, Joseph B ; Loeb, Lawrence AProceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14508-14513 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activityMaurer, Till ; Garrenton, Lindsay S ; Oh, Angela ; Pitts, Keith ; Anderson, Daniel J ; Skelton, Nicholas J ; Fauber, Benjamin P ; Pan, Borlan ; Malek, Shiva ; Stokoe, David ; Ludlam, Mary J. C ; Bowman, Krista K ; Wu, Jiansheng ; Giannetti, Anthony M ; Starovasnik, Melissa A ; Mellman, Ira ; Jackson, Peter K ; Rudolph, Joachim ; Wang, Weiru ; Fang, GuoweiProceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5299-5304 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish familyCámara-Checa, Anabel ; Perin, Francesca ; Rubio-Alarcón, Marcos ; Dago, María ; Crespo-García, Teresa ; Rapún, Josu ; Marín, María ; Cebrián, Jorge ; Gómez, Ricardo ; Bermúdez-Jiménez, Francisco ; Monserrat, Lorenzo ; Tamargo, Juan ; Caballero, Ricardo ; Jiménez-Jáimez, Juan ; Delpón, EvaProceedings of the National Academy of Sciences - PNAS, 2023-12, Vol.120 (49), p.e2305135120-e2305135120 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)Lucks, Julius B ; Mortimer, Stefanie A ; Trapnell, Cole ; Luo, Shujun ; Aviran, Sharon ; Schroth, Gary P ; Pachter, Lior ; Doudna, Jennifer A ; Arkin, Adam PProceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11063-11068 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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mRNA structure regulates protein expression through changes in functional half-lifeMauger, David M. ; Cabral, B. Joseph ; Presnyak, Vladimir ; Su, Stephen V. ; Reid, David W. ; Goodman, Brooke ; Link, Kristian ; Khatwani, Nikhil ; Reynders, John ; Moore, Melissa J. ; McFadyen, Iain J.Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (48), p.24075-24083 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Homology-independent discovery of replicating pathogenic circular RNAs by deep sequencing and a new computational algorithmWu, Qingfa ; Wang, Ying ; Cao, Mengji ; Pantaleo, Vitantonio ; Burgyan, Joszef ; Li, Wan-Xiang ; Ding, Shou-WeiProceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (10), p.3938-3943 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode arrayStranges, P. Benjamin ; Palla, Mirkó ; Kalachikov, Sergey ; Nivala, Jeff ; Dorwart, Michael ; Trans, Andrew ; Kumar, Shiv ; Porel, Mintu ; Chien, Minchen ; Tao, Chuanjuan ; Morozova, Irina ; Li, Zengmin ; Shi, Shundi ; Aberra, Aman ; Arnold, Cleoma ; Yang, Alexander ; Aguirre, Anne ; Harada, Eric T. ; Korenblum, Daniel ; Pollard, James ; Bhat, Ashwini ; Gremyachinskiy, Dmitriy ; Bibillo, Arek ; Chen, Roger ; Davis, Randy ; Russo, James J. ; Fuller, Carl W. ; Roever, Stefan ; Ju, Jingyue ; Church, George M.Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (44), p.E6749-E6756 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Elevated energy requirement of cone photoreceptorsIngram, Norianne T. ; Fain, Gordon L. ; Sampath, Alapakkam P.Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (32), p.19599-19603 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |