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1
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

Stein, Eytan M. ; Garcia-Manero, Guillermo ; Rizzieri, David A. ; Tibes, Raoul ; Berdeja, Jesus G. ; Savona, Michael R. ; Jongen-Lavrenic, Mojca ; Altman, Jessica K. ; Thomson, Blythe ; Blakemore, Stephen J. ; Daigle, Scott R. ; Waters, Nigel J. ; Suttle, A. Benjamin ; Clawson, Alicia ; Pollock, Roy ; Krivtsov, Andrei ; Armstrong, Scott A. ; DiMartino, Jorge ; Hedrick, Eric ; Löwenberg, Bob ; Tallman, Martin S.

Blood, 2018-06, Vol.131 (24), p.2661-2669 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy
Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy
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Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy

Mulligan, George ; Lichter, David I. ; Di Bacco, Alessandra ; Blakemore, Stephen J. ; Berger, Allison ; Koenig, Erik ; Bernard, Hugues ; Trepicchio, William ; Li, Bin ; Neuwirth, Rachel ; Chattopadhyay, Nibedita ; Bolen, Joseph B. ; Dorner, Andrew J. ; van de Velde, Helgi ; Ricci, Deborah ; Jagannath, Sundar ; Berenson, James R. ; Richardson, Paul G. ; Stadtmauer, Edward A. ; Orlowski, Robert Z. ; Lonial, Sagar ; Anderson, Kenneth C. ; Sonneveld, Pieter ; San Miguel, Jesús F. ; Esseltine, Dixie-Lee ; Schu, Matthew

Blood, 2014-01, Vol.123 (5), p.632-639 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
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Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Ljungström, Viktor ; Cortese, Diego ; Young, Emma ; Pandzic, Tatjana ; Mansouri, Larry ; Plevova, Karla ; Ntoufa, Stavroula ; Baliakas, Panagiotis ; Clifford, Ruth ; Sutton, Lesley-Ann ; Blakemore, Stuart J. ; Stavroyianni, Niki ; Agathangelidis, Andreas ; Rossi, Davide ; Höglund, Martin ; Kotaskova, Jana ; Juliusson, Gunnar ; Belessi, Chrysoula ; Chiorazzi, Nicholas ; Panagiotidis, Panagiotis ; Langerak, Anton W. ; Smedby, Karin E. ; Oscier, David ; Gaidano, Gianluca ; Schuh, Anna ; Davi, Frederic ; Pott, Christiane ; Strefford, Jonathan C. ; Trentin, Livio ; Pospisilova, Sarka ; Ghia, Paolo ; Stamatopoulos, Kostas ; Sjöblom, Tobias ; Rosenquist, Richard

Blood, 2016-02, Vol.127 (8), p.1007-1016 [Periódico revisado por pares]

United States: Elsevier Inc

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4
The Association between Deaths Due to Infection and Mutations of the BRAF, FBXW7, NRAS and XPO1 genes: A Report from the LRF CLL4 Trial
The Association between Deaths Due to Infection and Mutations of the BRAF, FBXW7, NRAS and XPO1 genes: A Report from the LRF CLL4 Trial
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The Association between Deaths Due to Infection and Mutations of the BRAF, FBXW7, NRAS and XPO1 genes: A Report from the LRF CLL4 Trial

Else, Monica ; Blakemore, Stuart J ; Strefford, Jonathan C ; Catovsky, Daniel

Blood, 2020-11, Vol.136 (Supplement 1), p.37-38 [Periódico revisado por pares]

Elsevier Inc

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5
PI3Kδ Inhibition Elicits Anti-Leukemic Effects through Bim-Dependent Apoptosis
PI3Kδ Inhibition Elicits Anti-Leukemic Effects through Bim-Dependent Apoptosis
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PI3Kδ Inhibition Elicits Anti-Leukemic Effects through Bim-Dependent Apoptosis

Carter, Matthew J ; Cox, Kerry L ; Blakemore, Stuart J ; Turaj, Anna H ; Oldham, Robert J ; Dahal, Lekh N. ; Tannheimer, Stacey ; Forconi, Francesco ; Packham, Graham ; Cragg, Mark S

Blood, 2016-12, Vol.128 (22), p.3241-3241 [Periódico revisado por pares]

Elsevier Inc

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6
The Incidence of Neonatal Abstinence Syndrome in Babies Born to Women with Sickle Cell Disease: A Single Center Study
The Incidence of Neonatal Abstinence Syndrome in Babies Born to Women with Sickle Cell Disease: A Single Center Study
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The Incidence of Neonatal Abstinence Syndrome in Babies Born to Women with Sickle Cell Disease: A Single Center Study

Anderson, Cynthia L ; Blakemore, Karin J ; Lanzkron, Sophie

Blood, 2012-11, Vol.120 (21), p.3225-3225 [Periódico revisado por pares]

Elsevier Inc

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7
Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study
Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study
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Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study

McDonald, Alice ; Thomas, Elizabeth ; Daigle, Scott ; Morschhauser, Franck ; Salles, Gilles ; Ribrag, Vincent ; McKay, Pamela ; Tilly, Herve ; Schmitt, Anna ; Batlevi, Connie Lee ; Fruchart, Christophe ; Johnson, Peter ; Dickinson, Michael ; Opat, Stephen ; Jurczak, Wojciech ; Cartron, Guillaume ; Lamy, Thierry ; Zinzani, Pier Luigi ; Assouline, Sarit ; Radford, John ; Gribben, John G. ; Haioun, Corinne ; Chaidos, Aristeidis ; Le Gouill, Steven ; Clawson, Alicia ; Larus, John ; Blakemore, Stephen J

Blood, 2018-11, Vol.132 (Supplement 1), p.4097-4097 [Periódico revisado por pares]

Elsevier Inc

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8
Interim Results from an Ongoing Phase 2 Multicenter Study of Tazemetostat, an EZH2 Inhibitor, in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Interim Results from an Ongoing Phase 2 Multicenter Study of Tazemetostat, an EZH2 Inhibitor, in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
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Interim Results from an Ongoing Phase 2 Multicenter Study of Tazemetostat, an EZH2 Inhibitor, in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Ribrag, Vincent ; Morschhauser, Franck ; McKay, Pamela ; Salles, Gilles Andre ; Batlevi, Connie Lee ; Schmitt, Anna ; Tilly, Herve ; Cartron, Guillaume ; Thieblemont, Catherine ; Fruchart, Christophe ; Gribben, John G. ; Lamy, Thierry ; Le Gouill, Steven ; Bouabdallah, Reda ; Dickinson, Michael ; Opat, Stephen ; Adib, Deyaa ; Blakemore, Stephen J ; Larus, John ; Johnson, Peter

Blood, 2018-11, Vol.132 (Supplement 1), p.4196-4196 [Periódico revisado por pares]

Elsevier Inc

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9
Final Report of Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Children with Relapsed or Refractory MLL-r Acute Leukemia
Final Report of Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Children with Relapsed or Refractory MLL-r Acute Leukemia
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Final Report of Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Children with Relapsed or Refractory MLL-r Acute Leukemia

Shukla, Neerav ; Wetmore, Cynthia ; O'Brien, Maureen M ; Silverman, Lewis B. ; Brown, Patrick ; Cooper, Todd M ; Thomson, Blythe ; Blakemore, Stephen J. ; Daigle, Scott ; Suttle, Ben ; Waters, Nigel J. ; Krivstov, Andrei V ; Armstrong, Scott A. ; Ho, Peter T ; Gore, Lia

Blood, 2016-12, Vol.128 (22), p.2780-2780 [Periódico revisado por pares]

Elsevier Inc

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10
Phase 1 Study of Tazemetostat (EPZ-6438), an Inhibitor of Enhancer of Zeste-Homolog 2 (EZH2): Preliminary Safety and Activity in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) Patients
Phase 1 Study of Tazemetostat (EPZ-6438), an Inhibitor of Enhancer of Zeste-Homolog 2 (EZH2): Preliminary Safety and Activity in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) Patients
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Phase 1 Study of Tazemetostat (EPZ-6438), an Inhibitor of Enhancer of Zeste-Homolog 2 (EZH2): Preliminary Safety and Activity in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) Patients

Ribrag, Vincent ; Soria, Jean-Charles ; Michot, Jean-Marie ; Schmitt, Anna ; Postel-Vinay, Sophie ; Bijou, Fontanet ; Thomson, Blythe ; Keilhack, Heike ; Blakemore, Stephen J. ; Reyderman, Larisa ; Kumar, Pavan ; Fine, Greg ; McDonald, Alice ; Ho, Peter T ; Italiano, Antoine

Blood, 2015-12, Vol.126 (23), p.473-473 [Periódico revisado por pares]

Elsevier Inc

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