Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria

Risitano, Antonio M. ; Ricklin, Daniel ; Huang, Yijun ; Reis, Edimara S. ; Chen, Hui ; Ricci, Patrizia ; Lin, Zhuoer ; Pascariello, Caterina ; Raia, Maddalena ; Sica, Michela ; Del Vecchio, Luigi ; Pane, Fabrizio ; Lupu, Florea ; Notaro, Rosario ; Resuello, Ranillo R.G. ; DeAngelis, Robert A. ; Lambris, John D.

United States: Elsevier Inc

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Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab

Kulasekararaj, Austin G. ; Risitano, Antonio M. ; Maciejewski, Jaroslaw P. ; Notaro, Rosario ; Browett, Peter ; Lee, Jong Wook ; Huang, Mingjun ; Geffner, Michael ; Brodsky, Robert A.

United States: Elsevier Inc

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Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab

Risitano, Antonio M. ; Notaro, Rosario ; Marando, Ludovica ; Serio, Bianca ; Ranaldi, Danilo ; Seneca, Elisa ; Ricci, Patrizia ; Alfinito, Fiorella ; Camera, Andrea ; Gianfaldoni, Giacomo ; Amendola, Angela ; Boschetti, Carla ; Di Bona, Eros ; Fratellanza, Giorgio ; Barbano, Filippo ; Rodeghiero, Francesco ; Zanella, Alberto ; Iori, Anna Paola ; Selleri, Carmine ; Luzzatto, Lucio ; Rotoli, Bruno

Washington, DC: Elsevier Inc

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Interaction Between Genotypes for HFE and TFR2 Genes Mutations and Iron Status in Brazilian Blood Donors

Cancado, Rodolfo D ; Santos, Paulo CJL ; Rostelato, Samuel ; Terada, Cristiane T ; Gonzales, Iris ; Hirata, Rosário DC ; Hirata, Mario H ; Chiattone, Carlos ; Guerra-Shinohara, Elvira M

Elsevier Inc

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Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

Rego, Eduardo M. ; Kim, Haesook T. ; Ruiz-Argüelles, Guillermo J. ; Undurraga, Maria Soledad ; Uriarte, Maria del Rosario ; Jacomo, Rafael H. ; Gutiérrez-Aguirre, Homero ; Melo, Raul A.M. ; Bittencourt, Rosane ; Pasquini, Ricardo ; Pagnano, Katia ; Fagundes, Evandro M. ; Chauffaille, Maria de Lourdes ; Chiattone, Carlos S. ; Martinez, Lem ; Meillón, Luis A. ; Gómez-Almaguer, David ; Kwaan, Hau C. ; Garcés-Eisele, Javier ; Gallagher, Robert ; Niemeyer, Charlotte M. ; Schrier, Stanley L. ; Tallman, Martin ; Grimwade, David ; Ganser, Arnold ; Berliner, Nancy ; Ribeiro, Raul C. ; Lo-Coco, Francesco ; Löwenberg, Bob ; Sanz, Miguel A.

United States: Elsevier Inc

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The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment

RISITANO, Antonio M ; NOTARO, Rosario ; LUZZATTO, Lucio ; MICHAEL HOLERS, V ; PASCARIELLO, Caterina ; SICA, Michela ; VECCHIO, Luigi Del ; HORVATH, Christopher J ; FRIDKIS-HARELI, Masha ; SELLERI, Carmine ; LINDORFER, Margaret A ; TAYLOR, Ronald P

Washington, DC: Americain Society of Hematology

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Genetic risk stratification to reduce inhibitor development in the early treatment of hemophilia A: a SIPPET analysis

Rosendaal, Frits R. ; Palla, Roberta ; Garagiola, Isabella ; Mannucci, Pier M. ; Peyvandi, Flora ; for the SIPPET Study Group

United States: Elsevier Inc

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Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies

Stein, Rhona ; Qu, Zhengxing ; Cardillo, Thomas M. ; Chen, Susan ; Rosario, Adriane ; Horak, Ivan D. ; Hansen, Hans J. ; Goldenberg, David M.

Washington, DC: Elsevier Inc

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Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial

Risitano, Antonio M ; Kulasekararaj, Austin ; Roeth, Alexander ; Scheinberg, Phillip ; Ueda, Yasutaka ; de Castro, Carlos ; Di Bona, Eros ; Griffin, Morag ; Langemeijer, Saskia MC ; Schrezenmeier, Hubert ; Barcellini, Wilma ; Mauad, Vitor AQ ; Panse, Jens ; Schafhausen, Philippe ; Tavitian, Suzanne ; Beggiato, Eloise ; Gaya, Anna ; Huang, Wei-Han ; Kitawaki, Toshio ; Kutlar, Abdullah ; Maciejewski, Jaroslaw P. ; Notaro, Rosario ; Pullarkat, Vinod ; Schubert, Jörg ; Terriou, Louis ; Uchiyama, Michihiro ; Sicre De Fontbrune, Flore ; Frieri, Camilla ; Alashkar, Ferras ; Gandhi, Shreyans ; Kumar, Rakesh ; Thorburn, Christine ; Maitra, Samopriyo ; Solar-Yohay, Susan ; Lawniczek, Tomasz ; Dahlke, Marion ; Peffault De Latour, Régis

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Mechanistic Evaluation of Efficacy Using Biomarkers of the Oral, Small Molecule Factor D Inhibitor, Danicopan (ACH-4471), in Untreated Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Risitano, Antonio M. ; Lee, Jong Wook ; Notaro, Rosario ; Brodsky, Robert A. ; Kulasekararaj, Austin ; Maciejewski, Jaroslaw P. ; Huang, Mingjun ; Geffner, Michael ; Browett, Peter

Elsevier Inc

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