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Material Type: Artigo
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Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's diseaseHermel, E ; Gafni, J ; Propp, S S ; Leavitt, B R ; Wellington, C L ; Young, J E ; Hackam, A S ; Logvinova, A V ; Peel, A L ; Chen, S F ; Hook, V ; Singaraja, R ; Krajewski, S ; Goldsmith, P C ; Ellerby, H M ; Hayden, M R ; Bredesen, D E ; Ellerby, L MCell death and differentiation, 2004-04, Vol.11 (4), p.424-438 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathiesSarkar, S ; Ravikumar, B ; Floto, R A ; Rubinsztein, D CCell death and differentiation, 2009-01, Vol.16 (1), p.46-56 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's DiseasePeng, Qi ; Wu, Bin ; Jiang, Mali ; Jin, Jing ; Hou, Zhipeng ; Zheng, Jennifer ; Zhang, Jiangyang ; Duan, Wenzhen Humbert, SandrinePloS one, 2016-02, Vol.11 (2), p.e0148839-e0148839 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesisLee, C. Y. Daniel ; Cantle, Jeffrey P. ; Yang, X. WilliamThe FEBS journal, 2013-09, Vol.280 (18), p.4382-4394 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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A new Caenorhabditis elegans model of human huntingtin 513 aggregation and toxicity in body wall musclesLee, Amy L ; Ung, Hailey M ; Sands, L Paul ; Kikis, Elise A van der Wel, PatrickPloS one, 2017-03, Vol.12 (3), p.e0173644 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's diseasevan Dellen, Anton ; Cordery, Patricia M ; Spires, Tara L ; Blakemore, Colin ; Hannan, Anthony JBMC neuroscience, 2008-04, Vol.9 (1), p.34-34, Article 34 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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Impaired Glucose Tolerance in the R6/1 Transgenic Mouse Model of Huntington's DiseaseJosefsen, K. ; Nielsen, M. D. ; Jørgensen, K. H. ; Bock, T. ; Nørremølle, A. ; Sørensen, S. A. ; Naver, B. ; Hasholt, L.Journal of neuroendocrinology, 2008-02, Vol.20 (2), p.165-172 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's diseaseEllrichmann, Gisa ; Petrasch-Parwez, Elisabeth ; Lee, De-Hyung ; Reick, Christiane ; Arning, Larissa ; Saft, Carsten ; Gold, Ralf ; Linker, Ralf A Kleinschnitz, ChristophPloS one, 2011-01, Vol.6 (1), p.e16172-e16172 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7Cryan, John F. ; Kelly, Peter H. ; Neijt, Hans C. ; Sansig, Gilles ; Flor, Peter J. ; Van Der Putten, HermanThe European journal of neuroscience, 2003-06, Vol.17 (11), p.2409-2417 [Periódico revisado por pares]Oxford, UK: Blackwell Science, LtdTexto completo disponível |
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Material Type: Artigo
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Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington diseaseKolodziejczyk, Karolina ; Parsons, Matthew P ; Southwell, Amber L ; Hayden, Michael R ; Raymond, Lynn A Fisone, GilbertoPloS one, 2014-04, Vol.9 (4), p.e94562-e94562 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |