Neoadjuvant pembrolizumab, dabrafenib and trametinib in BRAFV600-mutant resectable melanoma: the randomized phase 2 NeoTrio trial

Long, Georgina V. ; Carlino, Matteo S. ; Au-Yeung, George ; Spillane, Andrew J. ; Shannon, Kerwin F. ; Gyorki, David E. ; Hsiao, Edward ; Kapoor, Rony ; Thompson, Jake R. ; Batula, Iris ; Howle, Julie ; Ch’ng, Sydney ; Gonzalez, Maria ; Saw, Robyn P. M. ; Pennington, Thomas E. ; Lo, Serigne N. ; Scolyer, Richard A. ; Menzies, Alexander M.

Texto completo disponível

Anakinra in Sanfilippo syndrome: a phase 1/2 trial

Polgreen, Lynda E. ; Chen, Agnes H. ; Pak, Youngju ; Luzzi, Anna ; Morales Garval, Adolfo ; Acevedo, Jonathan ; Bitan, Gal ; Iacovino, Michelina ; O’Neill, Cara ; Eisengart, Julie B.

Texto completo disponível

Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial

Eijsvogel, Pepijn ; Misra, Pinaki ; Concha-Marambio, Luis ; Boyd, Justin D. ; Ding, Shuang ; Fedor, Lauren ; Hsieh, Yueh-Ting ; Sun, Yu Shuang ; Vroom, Madeline M. ; Farris, Carly M. ; Ma, Yihua ; de Kam, Marieke L. ; Radanovic, Igor ; Vissers, Maurits F. J. M. ; Mirski, Dario ; Shareghi, Ghazal ; Shahnawaz, Mohammad ; Singer, Wolfgang ; Kremer, Philip ; Groeneveld, Geert Jan ; Yu, Hui Jing ; Dodart, Jean-Cosme

Texto completo disponível

How to pay for individualized genetic medicines

Pian, Julia M. Y. ; Owusu, Nana ; Vitarello, Julia ; Yan, Winston X. ; Lo, Andrew W. ; Yu, Timothy W.

Texto completo disponível

Exploring the benefits, harms and costs of genomic newborn screening for rare diseases

Baple, Emma L. ; Scott, Richard H. ; Banka, Siddharth ; Buchanan, James ; Fish, Louise ; Wynn, Sarah ; Wilkinson, Dominic ; Ellard, Sian ; MacArthur, Daniel G. ; Stark, Zornitza

Texto completo disponível

Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial

Peters, Solange ; Gadgeel, Shirish M. ; Mok, Tony ; Nadal, Ernest ; Kilickap, Saadettin ; Swalduz, Aurélie ; Cadranel, Jacques ; Sugawara, Shunichi ; Chiu, Chao-Hua ; Yu, Chong-Jen ; Moskovitz, Mor ; Tanaka, Tomohiro ; Nersesian, Rhea ; Shagan, Sarah M. ; Maclennan, Margaret ; Mathisen, Michael ; Bhagawati-Prasad, Vijay ; Diarra, Cheick ; Assaf, Zoe June ; Archer, Venice ; Dziadziuszko, Rafal

Texto completo disponível

Meet the PrEP ambassadors who use social media to combat HIV

Adepoju, Paul

New York: Nature Publishing Group

Texto completo disponível

Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

Widman, Adam J ; Shah, Minita ; Frydendahl, Amanda ; Halmos, Daniel ; Khamnei, Cole C ; Øgaard, Nadia ; Rajagopalan, Srinivas ; Arora, Anushri ; Deshpande, Aditya ; Hooper, William F ; Quentin, Jean ; Bass, Jake ; Zhang, Mingxuan ; Langanay, Theophile ; Andersen, Laura ; Steinsnyder, Zoe ; Liao, Will ; Rasmussen, Mads Heilskov ; Henriksen, Tenna Vesterman ; Jensen, Sarah Østrup ; Nors, Jesper ; Therkildsen, Christina ; Sotelo, Jesus ; Brand, Ryan ; Schiffman, Joshua S ; Shah, Ronak H ; Cheng, Alexandre Pellan ; Maher, Colleen ; Spain, Lavinia ; Krause, Kate ; Frederick, Dennie T ; den Brok, Wendie ; Lohrisch, Caroline ; Shenkier, Tamara ; Simmons, Christine ; Villa, Diego ; Mungall, Andrew J ; Moore, Richard ; Zaikova, Elena ; Cerda, Viviana ; Kong, Esther ; Lai, Daniel ; Malbari, Murtaza S ; Marton, Melissa ; Manaa, Dina ; Winterkorn, Lara ; Gelmon, Karen ; Callahan, Margaret K ; Boland, Genevieve ; Potenski, Catherine ; Wolchok, Jedd D ; Saxena, Ashish ; Turajlic, Samra ; Imielinski, Marcin ; Berger, Michael F ; Aparicio, Sam ; Altorki, Nasser K ; Postow, Michael A ; Robine, Nicolas ; Andersen, Claus Lindbjerg ; Landau, Dan A

New York: Nature Publishing Group

Texto completo disponível

Estimating the total effect of anthropogenic climate change on human health and wellbeing

Ebi, Kristie L. ; Bowen, Kathryn ; Haines, Andy ; Hess, Jeremy J. ; Kovats, R. Sari ; Woodward, Alistair

Texto completo disponível

Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: a phase 1 trial

Bullock, Andrea J. ; Schlechter, Benjamin L. ; Fakih, Marwan G. ; Tsimberidou, Apostolia M. ; Grossman, Joseph E. ; Gordon, Michael S. ; Wilky, Breelyn A. ; Pimentel, Agustin ; Mahadevan, Daruka ; Balmanoukian, Ani S. ; Sanborn, Rachel E. ; Schwartz, Gary K. ; Abou-Alfa, Ghassan K. ; Segal, Neil H. ; Bockorny, Bruno ; Moser, Justin C. ; Sharma, Sunil ; Patel, Jaymin M. ; Wu, Wei ; Chand, Dhan ; Rosenthal, Katherine ; Mednick, Gabriel ; Delepine, Chloe ; Curiel, Tyler J. ; Stebbing, Justin ; Lenz, Heinz-Josef ; O’Day, Steven J. ; El-Khoueiry, Anthony B.

Texto completo disponível