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1
Conservation of Amino Acids in Human Rhinovirus 3C Protease Correlates with Broad-Spectrum Antiviral Activity of Rupintrivir, a Novel Human Rhinovirus 3C Protease Inhibitor
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Conservation of Amino Acids in Human Rhinovirus 3C Protease Correlates with Broad-Spectrum Antiviral Activity of Rupintrivir, a Novel Human Rhinovirus 3C Protease Inhibitor

BINFORD, S. L ; MALDONADO, F ; BROTHERS, M. A ; WEADY, P. T ; ZALMAN, L. S ; MEADOR, J. W ; MATTHEWS, D. A ; PATICK, A. K

Antimicrobial Agents and Chemotherapy, 2005-02, Vol.49 (2), p.619-626 [Revista revisada por pares]

Washington, DC: American Society for Microbiology

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2
In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease
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In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease

BINFORD, S. L ; WEADY, P. T ; MALDONADO, F ; BROTHERS, M. A ; MATTHEWS, D. A ; PATICK, A. K

Antimicrobial Agents and Chemotherapy, 2007-12, Vol.51 (12), p.4366-4373 [Revista revisada por pares]

Washington, DC: American Society for Microbiology

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3
In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease
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In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

PATICK, A. K ; BINFORD, S. L ; FUHRMAN, S. A ; MEADOR, J. W ; ZALMAN, L. S ; MATTHEWS, D. A ; WORLAND, S. T ; BROTHERS, M. A ; JACKSON, R. L ; FORD, C. E ; DIEM, M. D ; MALDONADO, F ; DRAGOVICH, P. S ; ZHOU, R ; PRINS, T. J

Antimicrobial Agents and Chemotherapy, 1999-10, Vol.43 (10), p.2444-2450 [Revista revisada por pares]

Washington, DC: American Society for Microbiology

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4
Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease
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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Webber, Stephen E. ; Tikhe, Jayashree ; Worland, Stephen T. ; Fuhrman, Shella A. ; Hendrickson, Thomas F. ; Matthews, David A. ; Love, Robert A. ; Patick, Amy K. ; Meador, James W. ; Ferre, Rose Ann ; Brown, Edward L. ; DeLisle, Dorothy M. ; Ford, Clifford E. ; Binford, Susan L.

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5072-5082 [Revista revisada por pares]

Washington, DC: American Chemical Society

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5
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Dragovich, Peter S ; Webber, Stephen E ; Babine, Robert E ; Fuhrman, Shella A ; Patick, Amy K ; Matthews, David A ; Lee, Caroline A ; Reich, Siegfried H ; Prins, Thomas J ; Marakovits, Joseph T ; Littlefield, Ethel S ; Zhou, Ru ; Tikhe, Jayashree ; Ford, Clifford E ; Wallace, Michael B ; Meador, James W ; Ferre, Rose Ann ; Brown, Edward L ; Binford, Susan L ; Harr, James E. V ; DeLisle, Dorothy M ; Worland, Stephen T

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2806-2818 [Revista revisada por pares]

Washington, DC: American Chemical Society

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6
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Dragovich, Peter S ; Webber, Stephen E ; Babine, Robert E ; Fuhrman, Shella A ; Patick, Amy K ; Matthews, David A ; Reich, Siegfried H ; Marakovits, Joseph T ; Prins, Thomas J ; Zhou, Ru ; Tikhe, Jayashree ; Littlefield, Ethel S ; Bleckman, Ted M ; Wallace, Michael B ; Little, Thomas L ; Ford, Clifford E ; Meador, James W ; Ferre, Rose Ann ; Brown, Edward L ; Binford, Susan L ; DeLisle, Dorothy M ; Worland, Stephen T

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2819-2834 [Revista revisada por pares]

Washington, DC: American Chemical Society

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7
Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors
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Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

DRAGOVICH, P. S ; RU ZHOU ; MEADOR, J. W ; PATICK, A. K ; FORD, C. E ; BROTHERS, M. A ; BINFORD, S. L ; MATTHEWS, D. A ; FERRE, R. A ; WORLAND, S. T ; WEBBER, S. E ; PRINS, T. J ; KWOK, A. K ; OKANO, K ; FUHRMAN, S. A ; ZALMAN, L. S ; MALDONADO, F. C ; BROWN, E. L

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.45-48 [Revista revisada por pares]

Oxford: Elsevier

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8
Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease:  Structure-Based Design, Synthesis, and Biological Evaluation
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Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease:  Structure-Based Design, Synthesis, and Biological Evaluation

Reich, Siegfried H ; Johnson, Theodore ; Wallace, Michael B ; Kephart, Susan E ; Fuhrman, Shella A ; Worland, Stephen T ; Matthews, David A ; Hendrickson, Thomas F ; Chan, Fora ; Meador, James ; Ferre, Rose Ann ; Brown, Edward L ; DeLisle, Dorothy M ; Patick, Amy K ; Binford, Susan L ; Ford, Clifford E

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1670-1683 [Revista revisada por pares]

United States: American Chemical Society

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9
Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids
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Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Dragovich, Peter S ; Webber, Stephen E ; Prins, Thomas J ; Zhou, Ru ; Marakovits, Joseph T ; Tikhe, Jayashree G ; Fuhrman, Shella A ; Patick, Amy K ; Matthews, David A ; Ford, Clifford E ; Brown, Edward L ; Binford, Susan L ; Meador, James W ; Ferre, Rose Ann ; Worland, Stephen T

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2189-2194 [Revista revisada por pares]

Oxford: Elsevier Ltd

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10
Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements
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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements

Webber, Stephen E. ; Okano, Koji ; Little, Thomas L. ; Reich, Siegfried H. ; Xin, Yue ; Fuhrman, Shella A. ; Matthews, David A. ; Love, Robert A. ; Hendrickson, Thomas F. ; Patick, Amy K. ; Meador, James W. ; Ferre, Rose Ann ; Brown, Edward L. ; Ford, Clifford E. ; Binford, Susan L. ; Worland, Stephen T.

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2786-2805 [Revista revisada por pares]

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