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Chronic Administration of Ion Channel Blockers Impact Microglia Morphology and Function in a Murine Model of Alzheimer’s DiseaseBoboc, Ianis Kevyn Stefan ; Cojocaru, Alexandru ; Nedelea, Gabriel ; Catalin, Bogdan ; Bogdan, Maria ; Calina, DanielaInternational journal of molecular sciences, 2023-10, Vol.24 (19), p.14474 [Periódico revisado por pares]Basel: MDPI AGTexto completo disponível |
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TREM2-Deficient Microglia Attenuate Tau Spreading In VivoLee-Gosselin, Audrey ; Jury-Garfe, Nur ; You, Yanwen ; Dabin, Luke ; Soni, Disha ; Dutta, Sayan ; Rochet, Jean-Christophe ; Kim, Jungsu ; Oblak, Adrian L ; Lasagna-Reeves, Cristian ACells (Basel, Switzerland), 2023-06, Vol.12 (12), p.1597 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Stereological Evidence of Non-Selective Hippocampal Neurodegeneration, IGF-1 Depletion, and Behavioral Deficit following Short Term Bilateral Adrenalectomy in Wistar RatsHamadi, Naserddine ; Deniz, Ömür Gülsüm ; Issa, Ahlam Said Abi ; Islam, Azim Ullah Shamsul ; Amir, Naheed ; Minhas, Saeed Tariq ; Madjid, Nather ; Khelifi-Touhami, Fatima ; Kaplan, Süleyman ; Adem, AbduBiomolecules (Basel, Switzerland), 2023-01, Vol.13 (1), p.22 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Novel Small Molecule Positive Allosteric Modulator SPAM1 Triggers the Nuclear Translocation of PAC1-R to Exert Neuroprotective Effects through Neuron-Restrictive Silencer FactorFan, Guangchun ; Chen, Shang ; Liang, Lili ; Zhang, Huahua ; Yu, RongjieInternational journal of molecular sciences, 2022-12, Vol.23 (24), p.15996 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal SexOcañas, Sarah R. ; Ansere, Victor A. ; Tooley, Kyla B. ; Hadad, Niran ; Chucair-Elliott, Ana J. ; Stanford, David R. ; Rice, Shannon ; Wronowski, Benjamin ; Pham, Kevin D. ; Hoffman, Jessica M. ; Austad, Steven N. ; Stout, Michael B. ; Freeman, Willard M.Molecular neurobiology, 2022-08, Vol.59 (8), p.4669-4702 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Efficacy of probucol on cognitive function in Alzheimer’s disease: study protocol for a double-blind, placebo-controlled, randomised phase II trial (PIA study)Lam, Virginie ; Clarnette, Roger ; Francis, Roslyn ; Bynevelt, Michael ; Watts, Gerald ; Flicker, Leon ; Orr, Carolyn F ; Loh, Poh ; Lautenschlager, Nicola ; Reid, Christopher M ; Foster, Jonathan K ; Dhaliwal, Satvinder S ; Robinson, Suzanne ; Corti, Emily ; Vaccarezza, Mauro ; Horgan, Ben ; Takechi, Ryusuke ; Mamo, JohnBMJ open, 2022-02, Vol.12 (2), p.e058826-e058826 [Periódico revisado por pares]England: British Medical Journal Publishing GroupTexto completo disponível |
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Material Type: Artigo
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A chemogenomic approach is required for effective treatment of amyotrophic lateral sclerosisPampalakis, Georgios ; Angelis, Georgios ; Zingkou, Eleni ; Vekrellis, Kostas ; Sotiropoulou, GeorgiaClinical and translational medicine, 2022-01, Vol.12 (1), p.e657-n/a [Periódico revisado por pares]United States: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Therapeutic potential of nanoemulsions as feasible wagons for targeting Alzheimer’s diseaseHanda, Mayank ; Tiwari, Sanjay ; Yadav, Awesh K. ; Almalki, Waleed H. ; Alghamdi, Saad ; Alharbi, Khalid S. ; Shukla, Rahul ; Beg, SarwarDrug discovery today, 2021-12, Vol.26 (12), p.2881-2888 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIAHo, Thao N T ; Abraham, Nikita ; Lewis, Richard JScientific reports, 2021-11, Vol.11 (1), p.21928-21928, Article 21928 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Neurodegenerative Disease: Roles for Sex, Hormones, and Oxidative StressSumien, Nathalie ; Cunningham, J Thomas ; Davis, Delaney L ; Engelland, Rachel ; Fadeyibi, Oluwadarasimi ; Farmer, George E ; Mabry, Steve ; Mensah-Kane, Paapa ; Trinh, Oanh T P ; Vann, Philip H ; Wilson, E Nicole ; Cunningham, Rebecca LEndocrinology (Philadelphia), 2021-11, Vol.162 (11), p.1 [Periódico revisado por pares]United States: Oxford University PressTexto completo disponível |