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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Herman, Sarah E.M. ; Gordon, Amber L. ; Hertlein, Erin ; Ramanunni, Asha ; Zhang, Xiaoli ; Jaglowski, Samantha ; Flynn, Joseph ; Jones, Jeffrey ; Blum, Kristie A. ; Buggy, Joseph J. ; Hamdy, Ahmed ; Johnson, Amy J. ; Byrd, John C.

Blood, 2011-06, Vol.117 (23), p.6287-6296 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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2
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
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Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

Shenoy, Niraj ; Bhagat, Tushar D ; Cheville, John ; Lohse, Christine ; Bhattacharyya, Sanchari ; Tischer, Alexander ; Machha, Venkata ; Gordon-Mitchell, Shanisha ; Choudhary, Gaurav ; Wong, Li-Fan ; Gross, LouAnn ; Ressigue, Emily ; Leibovich, Bradley ; Boorjian, Stephen A ; Steidl, Ulrich ; Wu, Xiaosheng ; Pradhan, Kith ; Gartrell, Benjamin ; Agarwal, Beamon ; Pagliaro, Lance ; Suzuki, Masako ; Greally, John M ; Rakheja, Dinesh ; Thompson, R Houston ; Susztak, Katalin ; Witzig, Thomas ; Zou, Yiyu ; Verma, Amit

The Journal of clinical investigation, 2019-04, Vol.129 (4), p.1612-1625 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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3
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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4
The emerging roles of forkhead box (Fox) proteins in cancer
The emerging roles of forkhead box (Fox) proteins in cancer
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The emerging roles of forkhead box (Fox) proteins in cancer

Lam, Eric W. -F ; Myatt, Stephen S

Nature reviews. Cancer, 2007-11, Vol.7 (11), p.847-859 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network
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Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network

Fish, Jason E ; Cantu Gutierrez, Manuel ; Dang, Lan T ; Khyzha, Nadiya ; Chen, Zhiqi ; Veitch, Shawn ; Cheng, Henry S ; Khor, Melvin ; Antounians, Lina ; Njock, Makon-Sébastien ; Boudreau, Emilie ; Herman, Alexander M ; Rhyner, Alexander M ; Ruiz, Oscar E ; Eisenhoffer, George T ; Medina-Rivera, Alejandra ; Wilson, Michael D ; Wythe, Joshua D

Development (Cambridge), 2017-07, Vol.144 (13), p.2428-2444 [Periódico revisado por pares]

England: The Company of Biologists Ltd

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6
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
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MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer

He, Wanming ; Liang, Bishan ; Wang, Chunlin ; Li, Shaowei ; Zhao, Yang ; Huang, Qiong ; Liu, Zexian ; Yao, Zhiqi ; Wu, Qijing ; Liao, Wangjun ; Zhang, Shuyi ; Liu, Yajing ; Xiang, Yi ; Liu, Jia ; Shi, Min

Oncogene, 2019-06, Vol.38 (23), p.4637-4654 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
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Childhood cerebellar tumours mirror conserved fetal transcriptional programs

Vladoiu, Maria C ; El-Hamamy, Ibrahim ; Donovan, Laura K ; Farooq, Hamza ; Holgado, Borja L ; Sundaravadanam, Yogi ; Ramaswamy, Vijay ; Hendrikse, Liam D ; Kumar, Sachin ; Mack, Stephen C ; Lee, John J Y ; Fong, Vernon ; Juraschka, Kyle ; Przelicki, David ; Michealraj, Antony ; Skowron, Patryk ; Luu, Betty ; Suzuki, Hiromichi ; Morrissy, A Sorana ; Cavalli, Florence M G ; Garzia, Livia ; Daniels, Craig ; Wu, Xiaochong ; Qazi, Maleeha A ; Singh, Sheila K ; Chan, Jennifer A ; Marra, Marco A ; Malkin, David ; Dirks, Peter ; Heisler, Lawrence ; Pugh, Trevor ; Ng, Karen ; Notta, Faiyaz ; Thompson, Eric M ; Kleinman, Claudia L ; Joyner, Alexandra L ; Jabado, Nada ; Stein, Lincoln ; Taylor, Michael D

Nature (London), 2019-08, Vol.572 (7767), p.67-73 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Mitochondrial DNA stress primes the antiviral innate immune response
Mitochondrial DNA stress primes the antiviral innate immune response
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Mitochondrial DNA stress primes the antiviral innate immune response

West, A Phillip ; Khoury-Hanold, William ; Staron, Matthew ; Tal, Michal C ; Pineda, Cristiana M ; Lang, Sabine M ; Bestwick, Megan ; Duguay, Brett A ; Raimundo, Nuno ; MacDuff, Donna A ; Kaech, Susan M ; Smiley, James R ; Means, Robert E ; Iwasaki, Akiko ; Shadel, Gerald S

Nature (London), 2015-04, Vol.520 (7548), p.553-557 [Periódico revisado por pares]

England: Nature Publishing Group

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9
DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Vanpouille-Box, Claire ; Alard, Amandine ; Aryankalayil, Molykutty J ; Sarfraz, Yasmeen ; Diamond, Julie M ; Schneider, Robert J ; Inghirami, Giorgio ; Coleman, C Norman ; Formenti, Silvia C ; Demaria, Sandra

Nature communications, 2017-06, Vol.8 (1), p.15618-15618, Article 15618 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase
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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

Garrett, Joan T ; Olivares, María Graciela ; Rinehart, Cammie ; Granja-Ingram, Nara D ; Sánchez, Violeta ; Chakrabarty, Anindita ; Dave, Bhuvanesh ; Cook, Rebecca S ; Pao, William ; McKinely, Eliot ; Manning, H.C ; Chang, Jenny ; Arteaga, Carlos L

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (12), p.5021-5026 [Periódico revisado por pares]

United States: National Academy of Sciences

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