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1
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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2
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
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MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer

He, Wanming ; Liang, Bishan ; Wang, Chunlin ; Li, Shaowei ; Zhao, Yang ; Huang, Qiong ; Liu, Zexian ; Yao, Zhiqi ; Wu, Qijing ; Liao, Wangjun ; Zhang, Shuyi ; Liu, Yajing ; Xiang, Yi ; Liu, Jia ; Shi, Min

Oncogene, 2019-06, Vol.38 (23), p.4637-4654 [Periódico revisado por pares]

England: Nature Publishing Group

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3
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

Burr, Marian L. ; Sparbier, Christina E. ; Chan, Kah Lok ; Chan, Yih-Chih ; Kersbergen, Ariena ; Lam, Enid Y.N. ; Azidis-Yates, Elizabeth ; Vassiliadis, Dane ; Bell, Charles C. ; Gilan, Omer ; Jackson, Susan ; Tan, Lavinia ; Wong, Stephen Q. ; Hollizeck, Sebastian ; Michalak, Ewa M. ; Siddle, Hannah V. ; McCabe, Michael T. ; Prinjha, Rab K. ; Guerra, Glen R. ; Solomon, Benjamin J. ; Sandhu, Shahneen ; Dawson, Sarah-Jane ; Beavis, Paul A. ; Tothill, Richard W. ; Cullinane, Carleen ; Lehner, Paul J. ; Sutherland, Kate D. ; Dawson, Mark A.

Cancer cell, 2019-10, Vol.36 (4), p.385-401.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome
Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome
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Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome

Mars, Ruben A.T. ; Yang, Yi ; Ward, Tonya ; Houtti, Mo ; Priya, Sambhawa ; Lekatz, Heather R. ; Tang, Xiaojia ; Sun, Zhifu ; Kalari, Krishna R. ; Korem, Tal ; Bhattarai, Yogesh ; Zheng, Tenghao ; Bar, Noam ; Frost, Gary ; Johnson, Abigail J. ; van Treuren, Will ; Han, Shuo ; Ordog, Tamas ; Grover, Madhusudan ; Sonnenburg, Justin ; D’Amato, Mauro ; Camilleri, Michael ; Elinav, Eran ; Segal, Eran ; Blekhman, Ran ; Farrugia, Gianrico ; Swann, Jonathan R. ; Knights, Dan ; Kashyap, Purna C.

Cell, 2020-09, Vol.182 (6), p.1460-1473.e17 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
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Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases

Ota, Mineto ; Nagafuchi, Yasuo ; Hatano, Hiroaki ; Ishigaki, Kazuyoshi ; Terao, Chikashi ; Takeshima, Yusuke ; Yanaoka, Haruyuki ; Kobayashi, Satomi ; Okubo, Mai ; Shirai, Harumi ; Sugimori, Yusuke ; Maeda, Junko ; Nakano, Masahiro ; Yamada, Saeko ; Yoshida, Ryochi ; Tsuchiya, Haruka ; Tsuchida, Yumi ; Akizuki, Shuji ; Yoshifuji, Hajime ; Ohmura, Koichiro ; Mimori, Tsuneyo ; Yoshida, Ken ; Kurosaka, Daitaro ; Okada, Masato ; Setoguchi, Keigo ; Kaneko, Hiroshi ; Ban, Nobuhiro ; Yabuki, Nami ; Matsuki, Kosuke ; Mutoh, Hironori ; Oyama, Sohei ; Okazaki, Makoto ; Tsunoda, Hiroyuki ; Iwasaki, Yukiko ; Sumitomo, Shuji ; Shoda, Hirofumi ; Kochi, Yuta ; Okada, Yukinori ; Yamamoto, Kazuhiko ; Okamura, Tomohisa ; Fujio, Keishi

Cell, 2021-05, Vol.184 (11), p.3006-3021.e17 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial
Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial
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Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Chiocca, E Antonio ; Yu, John S ; Lukas, Rimas V ; Solomon, Isaac H ; Ligon, Keith L ; Nakashima, Hiroshi ; Triggs, Daniel A ; Reardon, David A ; Wen, Patrick ; Stopa, Brittany M ; Naik, Ajay ; Rudnick, Jeremy ; Hu, Jethro L ; Kumthekar, Priya ; Yamini, Bakhtiar ; Buck, Jill Y ; Demars, Nathan ; Barrett, John A ; Gelb, Arnold B ; Zhou, John ; Lebel, Francois ; Cooper, Laurence J N

Science translational medicine, 2019-08, Vol.11 (505), p.1 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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7
The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment
The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment
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The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment

Brown, Timothy P ; Bhattacharjee, Pushpak ; Ramachandran, Sabarish ; Sivaprakasam, Sathish ; Ristic, Bojana ; Sikder, Mohd Omar F ; Ganapathy, Vadivel

Oncogene, 2020-04, Vol.39 (16), p.3292-3304 [Periódico revisado por pares]

England: Nature Publishing Group

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8
PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance
PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance
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PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance

Mukundan, Lata ; Odegaard, Justin I ; Morel, Christine R ; Heredia, Jose E ; Mwangi, Julia W ; Ricardo-Gonzalez, Roberto R ; Goh, Y P Sharon ; Eagle, Alex Red ; Dunn, Shannon E ; Awakuni, Jennifer U H ; Nguyen, Khoa D ; Steinman, Lawrence ; Michie, Sara A ; Chawla, Ajay

Nature medicine, 2009-11, Vol.15 (11), p.1266-1272 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer
Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer
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Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

Galluzzi, Lorenzo ; Vitale, Ilio ; Senovilla, Laura ; Olaussen, Ken André ; Pinna, Guillaume ; Eisenberg, Tobias ; Goubar, Aïcha ; Martins, Isabelle ; Michels, Judith ; Kratassiouk, Gueorgui ; Carmona-Gutierrez, Didac ; Scoazec, Marie ; Vacchelli, Erika ; Schlemmer, Frederic ; Kepp, Oliver ; Shen, Shensi ; Tailler, Maximilien ; Niso-Santano, Mireia ; Morselli, Eugenia ; Criollo, Alfredo ; Adjemian, Sandy ; Jemaà, Mohamed ; Chaba, Kariman ; Pailleret, Claire ; Michaud, Mickaël ; Pietrocola, Federico ; Tajeddine, Nicolas ; de La Motte Rouge, Thibault ; Araujo, Natalia ; Morozova, Nadya ; Robert, Thomas ; Ripoche, Hugues ; Commo, Frederic ; Besse, Benjamin ; Validire, Pierre ; Fouret, Pierre ; Robin, Angélique ; Dorvault, Nicolas ; Girard, Philippe ; Gouy, Sébastien ; Pautier, Patricia ; Jägemann, Nora ; Nickel, Ann-Christin ; Marsili, Sabrina ; Paccard, Caroline ; Servant, Nicolas ; Hupé, Philippe ; Behrens, Carmen ; Behnam-Motlagh, Parviz ; Kohno, Kimitoshi ; Cremer, Isabelle ; Damotte, Diane ; Alifano, Marco ; Midttun, Øivind ; Ueland, Per Magne ; Lazar, Vladimir ; Dessen, Philippe ; Zischka, Hans ; Chatelut, Etienne ; Castedo, Maria ; Madeo, Frank ; Barillot, Emmanuel ; Thomale, Juergen ; Wistuba, Ignacio Ivan ; Sautès-Fridman, Catherine ; Zitvogel, Laurence ; Soria, Jean-Charles ; Harel-Bellan, Annick ; Kroemer, Guido

Cell reports (Cambridge), 2012-08, Vol.2 (2), p.257-269 [Periódico revisado por pares]

United States: Elsevier Inc

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10
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Yang, Weiwei ; Xia, Yan ; Hawke, David ; Li, Xinjian ; Liang, Ji ; Xing, Dongming ; Aldape, Kenneth ; Hunter, Tony ; Alfred Yung, W.K. ; Lu, Zhimin

Cell, 2012-08, Vol.150 (4), p.685-696 [Periódico revisado por pares]

United States: Elsevier Inc

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