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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Herman, Sarah E.M. ; Gordon, Amber L. ; Hertlein, Erin ; Ramanunni, Asha ; Zhang, Xiaoli ; Jaglowski, Samantha ; Flynn, Joseph ; Jones, Jeffrey ; Blum, Kristie A. ; Buggy, Joseph J. ; Hamdy, Ahmed ; Johnson, Amy J. ; Byrd, John C.

Blood, 2011-06, Vol.117 (23), p.6287-6296 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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2
Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis
Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis
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Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis

SERMET-GAUDELUS, Isabelle ; DE BOECK, Kris ; MILLERS, Nilsen L ; CONSTANTINE, Scott ; REHA, Allen ; AJAYI, Temitayo ; ELFRING, Gary L ; MILLERS, Langdon L ; CASIMIR, Georges J ; VERMEULEN, François ; LEAL, Teresinha ; MOGENET, Agnès ; ROUSSEL, Delphine ; FRITSCH, Janine ; HANSSENS, Laurence ; HIRAWAT, Samit

American journal of respiratory and critical care medicine, 2010-11, Vol.182 (10), p.1262-1272 [Periódico revisado por pares]

New York, NY: American Thoracic Society

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3
Laminin alpha 2 enables glioblastoma stem cell growth
Laminin alpha 2 enables glioblastoma stem cell growth
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Laminin alpha 2 enables glioblastoma stem cell growth

Lathia, Justin D. ; Li, Meizhang ; Hall, Peter E. ; Gallagher, Joseph ; Hale, James S. ; Wu, Qiulian ; Venere, Monica ; Levy, Emily ; Rani, M.R. Sandhya ; Huang, Ping ; Bae, Eunnyung ; Selfridge, Julia ; Cheng, Lin ; Guvenc, Hacer ; McLendon, Roger E. ; Nakano, Ichiro ; Sloan, Andrew E. ; Phillips, Heidi S. ; Lai, Albert ; Gladson, Candece L. ; Bredel, Markus ; Bao, Shideng ; Hjelmeland, Anita B. ; Rich, Jeremy N.

Annals of neurology, 2012-11, Vol.72 (5), p.766-778 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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4
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
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Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

Hamilton, Jennifer D., PhD ; Suárez-Fariñas, Mayte, PhD ; Dhingra, Nikhil, BS ; Cardinale, Irma, MSc ; Li, Xuan, PhD ; Kostic, Ana, PhD ; Ming, Jeffrey E., MD, PhD ; Radin, Allen R., MD ; Krueger, James G., MD ; Graham, Neil, MD ; Yancopoulos, George D., MD, PhD ; Pirozzi, Gianluca, MD, PhD ; Guttman-Yassky, Emma, MD, PhD

Journal of allergy and clinical immunology, 2014-12, Vol.134 (6), p.1293-1300 [Periódico revisado por pares]

New York, NY: Elsevier Inc

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5
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
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IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

MARCUCCI, Guido ; MAHARRY, Kati ; METZELER, Klaus H ; POWELL, Bayard L ; CARTER, Thomas H ; KOLITZ, Jonathan E ; WETZLER, Meir ; CARROLL, Andrew J ; BAER, Maria R ; CALIGIURI, Michael A ; LARSON, Richard A ; BLOOMFIELD, Clara D ; WU, Yue-Zhong ; RADMACHER, Michael D ; MROZEK, Krzysztof ; MARGESON, Dean ; HOLLAND, Kelsi B ; WHITMAN, Susan P ; BECKER, Heiko ; SCHWIND, Sebastian

Journal of clinical oncology, 2010-05, Vol.28 (14), p.2348-2355 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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6
Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas
Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas
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Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas

SANSON, Marc ; MARIE, Yannick ; DELATTRE, Jean-Yves ; PARIS, Sophie ; IDBAIH, Ahmed ; LAFFAIRE, Julien ; DUCRAY, François ; EL HALLANI, Soufiane ; BOISSELIER, Blandine ; MOKHTARI, Karima ; HOANG-XUAN, Khe

Journal of clinical oncology, 2009-09, Vol.27 (25), p.4150-4154 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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7
Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes
Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes
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Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes

Kong, Ling-Chun ; Tap, Julien ; Aron-Wisnewsky, Judith ; Pelloux, Veronique ; Basdevant, Arnaud ; Bouillot, Jean-Luc ; Zucker, Jean-Daniel ; Doré, Joël ; Clément, Karine

The American journal of clinical nutrition, 2013-07, Vol.98 (1), p.16-24 [Periódico revisado por pares]

Bethesda, MD: American Society for Clinical Nutrition

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8
Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells
Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells
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Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

McNeill, Alisdair ; Magalhaes, Joana ; Shen, Chengguo ; Chau, Kai-Yin ; Hughes, Derralyn ; Mehta, Atul ; Foltynie, Tom ; Cooper, J. Mark ; Abramov, Andrey Y ; Gegg, Matthew ; Schapira, Anthony H.V

Brain (London, England : 1878), 2014-05, Vol.137 (5), p.1481-1495 [Periódico revisado por pares]

Oxford: Oxford University Press

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9
Evidence for a cross-talk between human neutrophils and Th17 cells
Evidence for a cross-talk between human neutrophils and Th17 cells
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Evidence for a cross-talk between human neutrophils and Th17 cells

Pelletier, Martin ; Maggi, Laura ; Micheletti, Alessandra ; Lazzeri, Elena ; Tamassia, Nicola ; Costantini, Claudio ; Cosmi, Lorenzo ; Lunardi, Claudio ; Annunziato, Francesco ; Romagnani, Sergio ; Cassatella, Marco A.

Blood, 2010-01, Vol.115 (2), p.335-343 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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10
miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1
miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1
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miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1

XIAOYONG HUANG ; TAEB, Samira ; BRISTOW, Robert G ; LIU, Fei-Fei ; LIU, Stanley K ; JAHANGIRI, Sahar ; EMMENEGGER, Urban ; TRAN, Elisa ; BRUCE, Jeff ; MESCI, Aruz ; KORPELA, Elina ; VESPRINI, Danny ; SHUN WONG, C

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (23), p.6972-6986 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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