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1 |
Material Type: Artigo
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Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signaturesHazlewood, Jessamine E ; Dumenil, Troy ; Le, Thuy T ; Slonchak, Andrii ; Kazakoff, Stephen H ; Patch, Ann-Marie ; Gray, Lesley-Ann ; Howley, Paul M ; Liu, Liang ; Hayball, John D ; Yan, Kexin ; Rawle, Daniel J ; Prow, Natalie A ; Suhrbier, Andreas McFadden, GrantPLoS pathogens, 2021-01, Vol.17 (1), p.e1009215 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastomaPoon, Evon ; Liang, Tong ; Jamin, Yann ; Walz, Susanne ; Kwok, Colin ; Hakkert, Anne ; Barker, Karen ; Urban, Zuzanna ; Thway, Khin ; Zeid, Rhamy ; Hallsworth, Albert ; Box, Gary ; Ebus, Marli E ; Licciardello, Marco P ; Sbirkov, Yordan ; Lazaro, Glori ; Calton, Elizabeth ; Costa, Barbara M ; Valenti, Melanie ; Brandon, Alexis De Haven ; Webber, Hannah ; Tardif, Nicolas ; Almeida, Gilberto S ; Christova, Rossitza ; Boysen, Gunther ; Richards, Mark W ; Barone, Giuseppe ; d, Anthony ; Bayliss, Richard ; Clarke, Paul A ; DE BONO, Johann ; Gray, Nathanael S ; Blagg, Julian ; Robinson, Simon P ; Eccles, Suzanne A ; Zheleva, Daniella ; Bradner, James E ; Molenaar, Jan ; Vivanco, Igor ; Eilers, Martin ; Workman, Paul ; Lin, Charles Y ; Chesler, LouisThe Journal of clinical investigation, 2020-11, Vol.130 (11), p.5875-5892 [Periódico revisado por pares]Ann Arbor: American Society for Clinical InvestigationTexto completo disponível |
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Material Type: Artigo
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Expanded encyclopaedias of DNA elements in the human and mouse genomesMoore, Jill E ; Purcaro, Michael J ; Pratt, Henry E ; Epstein, Charles B ; Shoresh, Noam ; Adrian, Jessika ; Kawli, Trupti ; Davis, Carrie A ; Dobin, Alexander ; Kaul, Rajinder ; Halow, Jessica ; Van Nostrand, Eric L ; Freese, Peter ; Gorkin, David U ; Shen, Yin ; He, Yupeng ; Mackiewicz, Mark ; Pauli-Behn, Florencia ; Williams, Brian A ; Mortazavi, Ali ; Keller, Cheryl A ; Zhang, Xiao-Ou ; Elhajjajy, Shaimae I ; Huey, Jack ; Dickel, Diane E ; Snetkova, Valentina ; Wei, Xintao ; Wang, Xiaofeng ; Rivera-Mulia, Juan Carlos ; Rozowsky, Joel ; Zhang, Jing ; Chhetri, Surya B ; Zhang, Jialing ; Victorsen, Alec ; White, Kevin P ; Visel, Axel ; Yeo, Gene W ; Burge, Christopher B ; Lécuyer, Eric ; Gilbert, David M ; Dekker, Job ; Rinn, John ; Mendenhall, Eric M ; Ecker, Joseph R ; Kellis, Manolis ; Klein, Robert J ; Noble, William S ; Kundaje, Anshul ; Guigó, Roderic ; Farnham, Peggy J ; Cherry, J Michael ; Myers, Richard M ; Ren, Bing ; Graveley, Brenton R ; Gerstein, Mark B ; Pennacchio, Len A ; Snyder, Michael P ; Bernstein, Bradley E ; Wold, Barbara ; Hardison, Ross C ; Gingeras, Thomas R ; Stamatoyannopoulos, John A ; Weng, ZhipingNature (London), 2020-07, Vol.583 (7818), p.699-710 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammationGilan, Omer ; Rioja, Inmaculada ; Knezevic, Kathy ; Bell, Matthew J ; Yeung, Miriam M ; Harker, Nicola R ; Lam, Enid Y N ; Chung, Chun-Wa ; Bamborough, Paul ; Petretich, Massimo ; Urh, Marjeta ; Atkinson, Stephen J ; Bassil, Anna K ; Roberts, Emma J ; Vassiliadis, Dane ; Burr, Marian L ; Preston, Alex G S ; Wellaway, Christopher ; Werner, Thilo ; Gray, James R ; Michon, Anne-Marie ; Gobbetti, Thomas ; Kumar, Vinod ; Soden, Peter E ; Haynes, Andrea ; Vappiani, Johanna ; Tough, David F ; Taylor, Simon ; Dawson, Sarah-Jane ; Bantscheff, Marcus ; Lindon, Matthew ; Drewes, Gerard ; Demont, Emmanuel H ; Daniels, Danette L ; Grandi, Paola ; Prinjha, Rab K ; Dawson, Mark AScience (American Association for the Advancement of Science), 2020-04, Vol.368 (6489), p.387-394 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibilityPatsopoulos, Nikolaos A. ; Baranzini, Sergio E. ; Santaniello, Adam ; Shoostari, Parisa ; Cotsapas, Chris ; Vlachos, Ioannis S. ; Pers, Tune H. ; Brandes, Aaron ; White, Charles ; Panteliadis, Ioannis-Pavlos ; Robbins, Allison ; Andlauer, Till F. M. ; Zarzycki, Onigiusz ; Dubois, Bénédicte ; Søndergaard, Helle Bach ; Sellebjerg, Finn ; Ullum, Henrik ; Saarela, Janna ; Cournu-Rebeix, Isabelle ; Damotte, Vincent ; Fontaine, Bertrand ; Guillot-Noel, Lena ; Lathrop, Mark ; Vukusic, Sandra ; Berthele, Achim ; Pongratz, Viola ; Buck, Dorothea ; Knier, Benjamin ; Lill, Christina M. ; Zipp, Frauke ; Amoroso, Antonio ; Barizzone, Nadia ; Cavalla, Paola ; Comi, Giancarlo ; Cusi, Daniele ; Esposito, Federica ; Ferrè, Laura ; Galimberti, Daniela ; Guaschino, Clara ; Martinelli, Vittorio ; Moiola, Lucia ; Salvetti, Marco ; Vecchio, Domizia ; Zauli, Andrea ; Santoro, Silvia ; Zuccalà, Miriam ; Mescheriakova, Julia ; van Duijn, Cornelia ; Celius, Elisabeth G. ; Spurkland, Anne ; Comabella, Manuel ; Montalban, Xavier ; Alfredsson, Lars ; Hillert, Jan ; Jagodic, Maja ; Lindén, Magdalena ; Piehl, Fredrik ; Martin, Roland ; Sospedra, Mirela ; Baker, Amie ; Ban, Maria ; Hawkins, Clive ; Kalra, Seema ; Khadake, Jyoti ; Molyneux, Paul ; Neville, Matthew ; Thorpe, John ; Bradshaw, Elizabeth ; Caillier, Stacy J. ; Cree, Bruce A. C. ; Davis, Mary ; de Bakker, Paul W. I. ; Delgado, Silvia ; Dembele, Marieme ; Edwards, Keith ; Gourraud, Pierre-Antoine ; Haines, Jonathan L ; Kimbrough, Dorlan ; Isobe, Noriko ; Lathi, Ellen ; Lee, Michelle H. ; An, David ; Zimmer, Andrew ; Manrique, Clara P. ; Mitrovic, Mitja ; Piccio, Laura ; Weiner, Howard ; Compston, Alastair ; Harbo, Hanne F. ; Hauser, Stephen L. ; Stewart, Graeme ; Hadjigeorgiou, Georgios ; Taylor, Bruce ; Booth, David ; Kockum, Ingrid ; Oksenberg, Jorge R. ; Sawcer, Stephen ; Ivinson, Adrian J. ; Olsson, Tomas ; De Jager, Philip L.Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6460), p.1417 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Small-molecule targeting of brachyury transcription factor addiction in chordomaSharifnia, Tanaz ; Wawer, Mathias J ; Chen, Ting ; Huang, Qing-Yuan ; Weir, Barbara A ; Sizemore, Ann ; Lawlor, Matthew A ; Goodale, Amy ; Cowley, Glenn S ; Vazquez, Francisca ; Ott, Christopher J ; Francis, Joshua M ; Sassi, Slim ; Cogswell, Patricia ; Sheppard, Hadley E ; Zhang, Tinghu ; Gray, Nathanael S ; Clarke, Paul A ; Blagg, Julian ; Workman, Paul ; Sommer, Josh ; Hornicek, Francis ; Root, David E ; Hahn, William C ; Bradner, James E ; Wong, Kwok K ; Clemons, Paul A ; Lin, Charles Y ; Kotz, Joanne D ; Schreiber, Stuart LNature medicine, 2019-02, Vol.25 (2), p.292-300 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The consensus molecular subtypes of colorectal cancerGuinney, Justin ; Dienstmann, Rodrigo ; Wang, Xin ; de Reyniès, Aurélien ; Schlicker, Andreas ; Soneson, Charlotte ; Marisa, Laetitia ; Roepman, Paul ; Nyamundanda, Gift ; Angelino, Paolo ; Bot, Brian M ; Morris, Jeffrey S ; Simon, Iris M ; Gerster, Sarah ; Fessler, Evelyn ; De Sousa E Melo, Felipe ; Missiaglia, Edoardo ; Ramay, Hena ; Barras, David ; Homicsko, Krisztian ; Maru, Dipen ; Manyam, Ganiraju C ; Broom, Bradley ; Boige, Valerie ; Perez-Villamil, Beatriz ; Laderas, Ted ; Salazar, Ramon ; Gray, Joe W ; Hanahan, Douglas ; Tabernero, Josep ; Bernards, Rene ; Friend, Stephen H ; Laurent-Puig, Pierre ; Medema, Jan Paul ; Sadanandam, Anguraj ; Wessels, Lodewyk ; Delorenzi, Mauro ; Kopetz, Scott ; Vermeulen, Louis ; Tejpar, SabineNature medicine, 2015-11, Vol.21 (11), p.1350-1356 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Erratum to: Modeling precision treatment of breast cancerDaemen, Anneleen ; Griffith, Obi L ; Heiser, Laura M ; Wang, Nicholas J ; Enache, Oana M ; Sanborn, Zachary ; Pepin, Francois ; Durinck, Steffen ; Korkola, James E ; Griffith, Malachi ; Hur, Joe S ; Huh, Nam ; Chung, Jongsuk ; Cope, Leslie ; Fackler, Mary Jo ; Umbricht, Christopher ; Sukumar, Saraswati ; Seth, Pankaj ; Sukhatme, Vikas P ; Jakkula, Lakshmi R ; Lu, Yiling ; Mills, Gordon B ; Cho, Raymond J ; Collisson, Eric A ; Van't Veer, Laura J ; Spellman, Paul T ; Gray, Joe WGenome Biology, 2015-05, Vol.16 (1), p.95-95, Article 95 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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Modeling precision treatment of breast cancerDaemen, Anneleen ; Griffith, Obi L ; Heiser, Laura M ; Wang, Nicholas J ; Enache, Oana M ; Sanborn, Zachary ; Pepin, Francois ; Durinck, Steffen ; Korkola, James E ; Griffith, Malachi ; Hur, Joe S ; Huh, Nam ; Chung, Jongsuk ; Cope, Leslie ; Fackler, Mary Jo ; Umbricht, Christopher ; Sukumar, Saraswati ; Seth, Pankaj ; Sukhatme, Vikas P ; Jakkula, Lakshmi R ; Lu, Yiling ; Mills, Gordon B ; Cho, Raymond J ; Collisson, Eric A ; van't Veer, Laura J ; Spellman, Paul T ; Gray, Joe WGenome Biology (Online Edition), 2013-01, Vol.14 (10), p.R110-R110 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparibDaemen, Anneleen ; Wolf, Denise M. ; Korkola, James E. ; Griffith, Obi L. ; Frankum, Jessica R. ; Brough, Rachel ; Jakkula, Lakshmi R. ; Wang, Nicholas J. ; Natrajan, Rachael ; Reis-Filho, Jorge S. ; Lord, Christopher J. ; Ashworth, Alan ; Spellman, Paul T. ; Gray, Joe W. ; van’t Veer, Laura J.Breast cancer research and treatment, 2012-09, Vol.135 (2), p.505-517 [Periódico revisado por pares]Boston: Springer USTexto completo disponível |