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MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy
MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy
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MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy

Chao, Jesse T ; Roskelley, Calvin D ; Loewen, Christopher J R

BMC bioinformatics, 2021-04, Vol.22 (1), p.202-202, Article 202 [Periódico revisado por pares]

England: BioMed Central Ltd

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Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction
Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction
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Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction

Post, Kathryn L ; Belmadani, Manuel ; Ganguly, Payel ; Meili, Fabian ; Dingwall, Riki ; McDiarmid, Troy A ; Meyers, Warren M ; Herrington, Caitlin ; Young, Barry P ; Callaghan, Daniel B ; Rogic, Sanja ; Edwards, Matthew ; Niciforovic, Ana ; Cau, Alessandro ; Rankin, Catharine H ; O'Connor, Timothy P ; Bamji, Shernaz X ; Loewen, Christopher J R ; Allan, Douglas W ; Pavlidis, Paul ; Haas, Kurt

Nature communications, 2020-04, Vol.11 (1), p.2073-2073, Article 2073 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Mito-Nuclear Interactions Affecting Lifespan and Neurodegeneration in a Drosophila Model of Leigh Syndrome
Mito-Nuclear Interactions Affecting Lifespan and Neurodegeneration in a Drosophila Model of Leigh Syndrome
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Mito-Nuclear Interactions Affecting Lifespan and Neurodegeneration in a Drosophila Model of Leigh Syndrome

Loewen, Carin A ; Ganetzky, Barry

Genetics (Austin), 2018-04, Vol.208 (4), p.1535-1552 [Periódico revisado por pares]

United States: Genetics Society of America

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4
Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in Saccharomyces cerevisiae
Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in Saccharomyces cerevisiae
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Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in Saccharomyces cerevisiae

Lawrence, Mackenzie B D ; Coutin, Nicolas ; Choi, Jennifer K ; Martin, Benjamin J E ; Irwin, Nicholas A T ; Young, Barry ; Loewen, Christopher ; Howe, LeAnn J

Genetics (Austin), 2017-09, Vol.207 (1), p.347-355 [Periódico revisado por pares]

United States: Genetics Society of America

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5
Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility
Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility
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Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility

Comyn, Sophie A ; Young, Barry P ; Loewen, Christopher J ; Mayor, Thibault Gardner, Richard

PLoS genetics, 2016-07, Vol.12 (7), p.e1006184 [Periódico revisado por pares]

United States: Public Library of Science

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6
Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor
Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor
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Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor

Choudhary, Pooja ; Loewen, Michele C

Journal of biochemistry (Tokyo), 2016-01, Vol.159 (1), p.49-58 [Periódico revisado por pares]

England: Oxford University Press

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7
A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria: e1001969
A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria: e1001969
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A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria: e1001969

Lahiri, Sujoy ; Chao, Jesse T ; Tavassoli, Shabnam ; Wong, Andrew KO ; Choudhary, Vineet ; Young, Barry P ; Loewen, Christopher JR ; Prinz, William A

PLoS biology, 2014-10, Vol.12 (10) [Periódico revisado por pares]

San Francisco: Public Library of Science

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8
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria
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A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria

Lahiri, Sujoy ; Chao, Jesse T ; Tavassoli, Shabnam ; Wong, Andrew K O ; Choudhary, Vineet ; Young, Barry P ; Loewen, Christopher J R ; Prinz, William A Schmid, Sandra L.

PLoS biology, 2014-10, Vol.12 (10), p.e1001969-e1001969 [Periódico revisado por pares]

United States: Public Library of Science

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9
Genetic variation of six desaturase genes in flax and their impact on fatty acid composition
Genetic variation of six desaturase genes in flax and their impact on fatty acid composition
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Genetic variation of six desaturase genes in flax and their impact on fatty acid composition

Thambugala, Dinushika ; Duguid, Scott ; Loewen, Evelyn ; Rowland, Gordon ; Booker, Helen ; You, Frank M ; Cloutier, Sylvie

Theoretical and applied genetics, 2013-10, Vol.126 (10), p.2627-2641 [Periódico revisado por pares]

Berlin/Heidelberg: Springer-Verlag

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10
Chemical and biological characterization of sclerosin, an antifungal lipopeptide
Chemical and biological characterization of sclerosin, an antifungal lipopeptide
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Chemical and biological characterization of sclerosin, an antifungal lipopeptide

Berry, Chrystal L ; Brassinga, Ann Karen C ; Donald, Lynda J ; Fernando, W.G. Dilantha ; Loewen, Peter C ; de Kievit, Teresa R

Canadian journal of microbiology, 2012-08, Vol.58 (8), p.1027-1034 [Periódico revisado por pares]

Ottawa, ON: NRC Research Press

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