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Refinado por: Nome da Publicação: Journal Of Medicinal Chemistry remover assunto: Structure-Activity Relationship remover Life Sciences & Biomedicine remover
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1
Aldosterone antagonists. 2. New 7 alpha-(acetylthio)-15,16-methylene spirolactones
Aldosterone antagonists. 2. New 7 alpha-(acetylthio)-15,16-methylene spirolactones
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Aldosterone antagonists. 2. New 7 alpha-(acetylthio)-15,16-methylene spirolactones

Nickisch, K ; Bittler, D ; Laurent, H ; Losert, W ; Casals-Stenzel, J ; Nishino, Y ; Schillinger, E ; Wiechert, R

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1403-1409 [Periódico revisado por pares]

United States

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2
Aldosterone antagonists. 3. Synthesis and activities of steroidal 7 alpha-(alkoxycarbonyl)-15,16-methylene spirolactones
Aldosterone antagonists. 3. Synthesis and activities of steroidal 7 alpha-(alkoxycarbonyl)-15,16-methylene spirolactones
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Aldosterone antagonists. 3. Synthesis and activities of steroidal 7 alpha-(alkoxycarbonyl)-15,16-methylene spirolactones

Nickisch, K ; Bittler, D ; Laurent, H ; Losert, W ; Nishino, Y ; Schillinger, E ; Wiechert, R

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.509-513 [Periódico revisado por pares]

United States

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3
Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo[1,2-a]pyrazines
Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo[1,2-a]pyrazines
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Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo[1,2-a]pyrazines

Bonnet, Pierre A ; Michel, Alain ; Laurent, Florence ; Sablayrolles, Claire ; Rechencq, Eliane ; Mani, Jean C ; Boucard, Maurice ; Chapat, Jean P

Journal of medicinal chemistry, 1992-09, Vol.35 (18), p.3353-3358 [Periódico revisado por pares]

WASHINGTON: American Chemical Society

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4
New Benzocycloalkylpiperazines, Potent and Selective 5-HT1A Receptor Ligands
New Benzocycloalkylpiperazines, Potent and Selective 5-HT1A Receptor Ligands
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New Benzocycloalkylpiperazines, Potent and Selective 5-HT1A Receptor Ligands

El Ahmad, Youssef ; Laurent, Elisabeth ; Maillet, Philippe ; Talab, Akram ; Teste, Jean François ; Dokhan, Raymond ; Tran, Gilles ; Ollivier, Roland

Journal of medicinal chemistry, 1997-03, Vol.40 (6), p.952-960 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity
Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity
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Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Schultz, Christiane ; Link, Andreas ; Leost, Maryse ; Zaharevitz, Daniel W ; Gussio, Rick ; Sausville, Edward A ; Meijer, Laurent ; Kunick, Conrad

Journal of medicinal chemistry, 1999-07, Vol.42 (15), p.2909-2919 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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6
Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors
Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors
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Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors

Hennequin, Laurent F ; Thomas, Andrew P ; Johnstone, Craig ; Stokes, Elaine S. E ; Plé, Patrick A ; Lohmann, Jean-Jacques M ; Ogilvie, Donald J ; Dukes, Mike ; Wedge, Steve R ; Curwen, Jon O ; Kendrew, Jane ; Lambert-van der Brempt, Christine

Journal of medicinal chemistry, 1999-12, Vol.42 (26), p.5369-5389 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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7
New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis
New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis
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New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis

Bold, Guido ; Altmann, Karl-Heinz ; Frei, Jörg ; Lang, Marc ; Manley, Paul W ; Traxler, Peter ; Wietfeld, Bernhard ; Brüggen, Josef ; Buchdunger, Elisabeth ; Cozens, Robert ; Ferrari, Stefano ; Furet, Pascal ; Hofmann, Francesco ; Martiny-Baron, Georg ; Mestan, Jürgen ; Rösel, Johannes ; Sills, Matthew ; Stover, David ; Acemoglu, Figan ; Boss, Eugen ; Emmenegger, René ; Lässer, Laurent ; Masso, Elvira ; Roth, Rosemarie ; Schlachter, Christian ; Vetterli, Werner ; Wyss, Dominique ; Wood, Jeanette M

Journal of medicinal chemistry, 2000-06, Vol.43 (12), p.2310-2323 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
Design, Synthesis and Pharmacological Characterization of a Potent Radioiodinated and Photoactivatable Peptidic Oxytocin Antagonist
Design, Synthesis and Pharmacological Characterization of a Potent Radioiodinated and Photoactivatable Peptidic Oxytocin Antagonist
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Design, Synthesis and Pharmacological Characterization of a Potent Radioiodinated and Photoactivatable Peptidic Oxytocin Antagonist

Carnazzi, Eric ; Aumelas, André ; Mouillac, Bernard ; Breton, Christophe ; Guillou, Laurent ; Barberis, Claude ; Seyer, René

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.3022-3030 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
Novel 4-Anilinoquinazolines with C-7 Basic Side Chains:  Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors
Novel 4-Anilinoquinazolines with C-7 Basic Side Chains:  Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors
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Novel 4-Anilinoquinazolines with C-7 Basic Side Chains:  Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors

Hennequin, Laurent F ; Stokes, Elaine S. E ; Thomas, Andrew P ; Johnstone, Craig ; Plé, Patrick A ; Ogilvie, Donald J ; Dukes, Michael ; Wedge, Stephen R ; Kendrew, Jane ; Curwen, Jon O

Journal of medicinal chemistry, 2002-03, Vol.45 (6), p.1300-1312 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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10
Structure-Based Design and Synthesis of 2-Benzylidene-benzofuran-3-ones as Flavopiridol Mimics
Structure-Based Design and Synthesis of 2-Benzylidene-benzofuran-3-ones as Flavopiridol Mimics
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Structure-Based Design and Synthesis of 2-Benzylidene-benzofuran-3-ones as Flavopiridol Mimics

Schoepfer, Joseph ; Fretz, Heinz ; Chaudhuri, Bhabatosh ; Muller, Lionel ; Seeber, Egge ; Meijer, Laurent ; Lozach, Olivier ; Vangrevelinghe, Eric ; Furet, Pascal

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1741-1747 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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