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Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes
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Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes

Antcliffe, David Benjamin ; Mi, Yuxin ; Santhakumaran, Shalini ; Burnham, Katie L ; Prevost, A Toby ; Ward, Josie K ; Marshall, Timothy J ; Bradley, Claire ; Al-Beidh, Farah ; Hutton, Paula ; McKechnie, Stuart ; Davenport, Emma E ; Hinds, Charles J ; O'Kane, Cecilia M ; McAuley, Daniel Francis ; Shankar-Hari, Manu ; Gordon, Anthony C ; Knight, Julian C

Thorax, 2024-06, Vol.79 (6), p.515-523 [Periódico revisado por pares]

England: BMJ Publishing Group Ltd and British Thoracic Society

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2
Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes
Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes
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Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes

Gilchrist, James J. ; Fang, Hai ; Danielli, Sara ; Tomkova, Marketa ; Nassiri, Isar ; Ng, Esther ; Tong, Orion ; Taylor, Chelsea ; Muldoon, Dylan ; Cohen, Lea R.Z. ; Al-Mossawi, Hussein ; Lau, Evelyn ; Neville, Matt ; Schuster-Boeckler, Benjamin ; Knight, Julian C. ; Fairfax, Benjamin P.

Cell genomics, 2024-05, Vol.4 (5), p.100541-100541, Article 100541 [Periódico revisado por pares]

United States: Elsevier Inc

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3
An immunodominant NP105-113-B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
An immunodominant NP105-113-B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
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An immunodominant NP105-113-B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Peng, Yanchun ; Felce, Suet Ling ; Dong, Danning ; Penkava, Frank ; Mentzer, Alexander J ; Yao, Xuan ; Liu, Guihai ; Yin, Zixi ; Chen, Ji-Li ; Lu, Yongxu ; Wellington, Dannielle ; Wing, Peter AC ; Dominey-Foy, Delaney CC ; Jin, Chen ; Wang, Wenbo ; Hamid, Megat Abd ; Fernandes, Ricardo A ; Wang, Beibei ; Fries, Anastasia ; Zhuang, Xiaodong ; Ashley, Neil ; Rostron, Timothy ; Waugh, Craig ; Sopp, Paul ; Hublitz, Philip ; Beveridge, Ryan ; Tan, Tiong Kit ; Dold, Christina ; Kwok, Andrew J ; Rich-Griffin, Charlotte ; Dejnirattisa, Wanwisa ; Liu, Chang ; Kurupati, Prathiba ; Nassiri, Isar ; Watson, Robert A ; Tong, Orion ; Taylor, Chelsea A ; Kumar Sharma, Piyush ; Sun, Bo ; Curion, Fabiola ; Revale, Santiago ; Garner, Lucy C ; Jansen, Kathrin ; Ferreira, Ricardo C ; Attar, Moustafa ; Fry, Jeremy W ; Russell, Rebecca A ; COMBAT Consortium ; Stauss, Hans J ; James, William ; Townsend, Alain ; Ho, Ling-Pei ; Klenerman, Paul ; Mongkolsapaya, Juthathip ; Screaton, Gavin R ; Dendrou, Calliope ; Sansom, Stephen N ; Bashford-Rogers, Rachael ; Chain, Benny ; Smith, Geoffrey L ; McKeating, Jane A ; Fairfax, Benjamin P ; Bowness, Paul ; McMichael, Andrew J ; Ogg, Graham ; Knight, Julian C ; Dong, Tao

http://dx.doi.org/10.1038/s41590-021-01084-z 2022-01

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4
An immunodominant NP 105-113 -B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
An immunodominant NP 105-113 -B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
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An immunodominant NP 105-113 -B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Peng, Yanchun ; Felce, Suet Ling ; Dong, Danning ; Penkava, Frank ; Mentzer, Alexander J ; Yao, Xuan ; Liu, Guihai ; Yin, Zixi ; Chen, Ji-Li ; Lu, Yongxu ; Wellington, Dannielle ; Wing, Peter A C ; Dominey-Foy, Delaney C C ; Jin, Chen ; Wang, Wenbo ; Hamid, Megat Abd ; Fernandes, Ricardo A ; Wang, Beibei ; Fries, Anastasia ; Zhuang, Xiaodong ; Ashley, Neil ; Rostron, Timothy ; Waugh, Craig ; Sopp, Paul ; Hublitz, Philip ; Beveridge, Ryan ; Tan, Tiong Kit ; Dold, Christina ; Kwok, Andrew J ; Rich-Griffin, Charlotte ; Dejnirattisa, Wanwisa ; Liu, Chang ; Kurupati, Prathiba ; Nassiri, Isar ; Watson, Robert A ; Tong, Orion ; Taylor, Chelsea A ; Kumar Sharma, Piyush ; Sun, Bo ; Curion, Fabiola ; Revale, Santiago ; Garner, Lucy C ; Jansen, Kathrin ; Ferreira, Ricardo C ; Attar, Moustafa ; Fry, Jeremy W ; Russell, Rebecca A ; Stauss, Hans J ; James, William ; Townsend, Alain ; Ho, Ling-Pei ; Klenerman, Paul ; Mongkolsapaya, Juthathip ; Screaton, Gavin R ; Dendrou, Calliope ; Sansom, Stephen N ; Bashford-Rogers, Rachael ; Chain, Benny ; Smith, Geoffrey L ; McKeating, Jane A ; Fairfax, Benjamin P ; Bowness, Paul ; McMichael, Andrew J ; Ogg, Graham ; Knight, Julian C ; Dong, Tao

Nature immunology, 2022-01, Vol.23 (1), p.50 [Periódico revisado por pares]

United States

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5
Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders
Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders
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Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders

Hargreaves, Chantal E. ; Salatino, Silvia ; Sasson, Sarah C. ; Charlesworth, James E. G. ; Bateman, Elizabeth ; Patel, Arzoo M. ; Anzilotti, Consuelo ; Broxholme, John ; Knight, Julian C. ; Patel, Smita Y.

Journal of clinical immunology, 2021-08, Vol.41 (6), p.1315-1330 [Periódico revisado por pares]

New York: Springer US

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6
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
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Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

Knight, Stephen R ; Holden, Karl A ; Merson, Laura ; Russell, Clark D ; Solomon, Tom ; Carson, Gail ; Olliaro, Piero ; Semple, Malcolm G ; Alex, Beatrice ; Bach, Benjamin ; Dunning, Jake ; da Silva Filipe, Ana ; Horby, Peter W ; Law, Andrew ; Price, Nicholas ; Rambaut, Andrew ; Robertson, David L ; Scott, Janet T ; de Silva, Thushan ; Sigfrid, Louise ; Tedder, Richard S ; Thwaites, Ryan S ; Turtle, Lance CW ; Andrikopoulos, Petros ; Liggi, Sonia ; Sands, Caroline ; Fairfield, Cameron J ; Shaw, Catherine A ; Dalton, Jo ; Girvan, Michelle ; Hendry, Ross ; Greenhalf, William ; McDonald, Sarah E ; Booth, Laura ; Catterall, Benjamin WA ; Clarke, Emily A ; Dincarslan, Oslem ; Dyer, Philip ; Gunning, Philip ; Hartley, Catherine ; Jensen, Rebecca L ; Jones, Christopher B ; Khandaker, Shadia ; Lefteri, Daniella ; Livoti, Lucia A ; Middleton, Joanna ; Reynolds, Will ; Ridley, P. Matthew ; Shaw, Victoria E ; Tanianis-Hughes, Jolanta ; Trochu, Erwan ; Flaherty, Lisa ; Massey, Hannah ; Aldera, Erin L. ; Alegria, Ana ; Barnass, Stella ; Barrett, Nicholas ; Basude, Sneha ; Baxter, David ; Beadsworth, Michael ; Best, Nicola ; Burden, Tom ; Chukkambotla, Srikanth ; Cutino-Moguel, Maria-Teresa ; Douthwaite, Sam ; Fullerton, Duncan ; Garg, Atul ; Hawcutt, Daniel B ; Jennings, Paul ; Kaliappan, Agilan ; Kasipandian, Vidya ; Koduri, Gouri ; Laird, Steven ; Leiner, Tamas ; Little, Jeff ; McEwen, Ruth ; Morris, Craig ; Moses, Samuel ; Norris, Lillian ; Panchatsharam, Selva ; Pattison, Natalie ; Peters, Mark ; Price, David ; Prout, Rachel ; Richardson, Neil ; Rousseau, Guy ; Ryan, Brendan ; Sharma, Anil ; Stambach, Tom ; Stewart, Richard ; Thompson, Robert ; Tridente, Ascanio ; Vuylsteke, Alan ; Waddy, Sam ; Wake, Rachel ; Wilson, Lawrence ; Wiselka, Martin ; Wootton, Daniel G ; Workman, Andrew ; Young, Peter

The Lancet (British edition), 2021-07, Vol.398 (10296), p.223-237 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7
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Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

Davies, Nicholas G ; Jarvis, Christopher I ; Edmunds, W John ; Jewell, Nicholas P ; Diaz-Ordaz, Karla ; Keogh, Ruth H

Nature (London), 2021-05, Vol.593 (7858), p.270-274 [Periódico revisado por pares]

England: Nature Publishing Group

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8
The impact of local and national restrictions in response to COVID-19 on social contacts in England: a longitudinal natural experiment
The impact of local and national restrictions in response to COVID-19 on social contacts in England: a longitudinal natural experiment
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The impact of local and national restrictions in response to COVID-19 on social contacts in England: a longitudinal natural experiment

Jarvis, Christopher I ; Gimma, Amy ; van Zandvoort, Kevin ; Wong, Kerry L M ; Edmunds, W John

BMC medicine, 2021-02, Vol.19 (1), p.52-52, Article 52 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study
Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study
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Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study

Clark, Andrew ; Jit, Mark ; Warren-Gash, Charlotte ; Guthrie, Bruce ; Wang, Harry H X ; Mercer, Stewart W ; Sanderson, Colin ; McKee, Martin ; Troeger, Christopher ; Ong, Kanyin L ; Checchi, Francesco ; Perel, Pablo ; Joseph, Sarah ; Gibbs, Hamish P ; Banerjee, Amitava ; Eggo, Rosalind M ; Nightingale, Emily S ; O'Reilly, Kathleen ; Jombart, Thibaut ; Edmunds, W John ; Rosello, Alicia ; Sun, Fiona Yueqian ; Atkins, Katherine E ; Bosse, Nikos I ; Clifford, Samuel ; Russell, Timothy W ; Deol, Arminder K ; Liu, Yang ; Procter, Simon R ; Leclerc, Quentin J ; Medley, Graham ; Knight, Gwen ; Munday, James D ; Kucharski, Adam J ; Pearson, Carl A B ; Klepac, Petra ; Prem, Kiesha ; Houben, Rein M G J ; Endo, Akira ; Flasche, Stefan ; Davies, Nicholas G ; Diamond, Charlie ; van Zandvoort, Kevin ; Funk, Sebastian ; Auzenbergs, Megan ; Rees, Eleanor M ; Tully, Damien C ; Emery, Jon C ; Quilty, Billy J ; Abbott, Sam ; Villabona-Arenas, Ch Julian ; Hué, Stéphane ; Hellewell, Joel ; Gimma, Amy ; Jarvis, Christopher I

The Lancet global health, 2020-08, Vol.8 (8), p.e1003-e1017 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease
Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease
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Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease

Zhao, Yan ; Qin, Ling ; Zhang, Ping ; Li, Kang ; Liang, Lianchun ; Sun, Jianping ; Xu, Bin ; Dai, Yanchao ; Li, Xuemei ; Zhang, Chi ; Peng, Yanchun ; Feng, Yingmei ; Li, Ang ; Hu, Zhongjie ; Xiang, Haiping ; Ogg, Graham ; Ho, Ling-Pei ; McMichael, Andrew ; Jin, Ronghua ; Knight, Julian C ; Dong, Tao ; Zhang, Yonghong

JCI insight, 2020-07, Vol.5 (13) [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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