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Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2⁺ breast cancer patientsScaltriti, Maurizio ; Eichhorn, Pieter J ; Cortés, Javier ; Prudkin, Ludmila ; Aura, Claudia ; Jiménez, José ; Chandarlapaty, Sarat ; Serra, Violeta ; Prat, Aleix ; Ibrahim, Yasir H ; Guzmán, Marta ; Gili, Magui ; Rodríguez, Olga ; Rodríguez, Sonia ; Pérez, José ; Green, Simon R ; Mai, Sabine ; Rosen, Neal ; Hudis, Clifford ; Baselga, JoséProceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (9), p.3761-3766 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell responseGangaev, Anastasia ; Rozeman, Elisa A ; Rohaan, Maartje W ; Isaeva, Olga I ; Philips, Daisy ; Patiwael, Sanne ; van den Berg, Joost H ; Ribas, Antoni ; Schadendorf, Dirk ; Schilling, Bastian ; Schumacher, Ton N ; Blank, Christian U ; Haanen, John B A G ; Kvistborg, PiaProceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (43) [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor–mediated upregulation of caveolin-1Wang, Yi ; Roche, Olga ; Xu, Chaoying ; Moriyama, Eduardo H ; Heir, Pardeep ; Chung, Jacky ; Roos, Frederik C ; Chen, Yonghong ; Finak, Greg ; Milosevic, Michael ; Wilson, Brian C ; Teh, Bin Tean ; Park, Morag ; Irwin, Meredith S ; Ohh, MichaelProceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (13), p.4892-4897 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinomaJiang, Xiaomo ; Hao, Huai-Xiang ; Growney, Joseph D. ; Woolfenden, Steve ; Bottiglio, Cindy ; Ng, Nicholas ; Lu, Bo ; Hsieh, Mindy H. ; Bagdasarian, Linda ; Meyer, Ronald ; Smith, Timothy R. ; Avello, Monika ; Charlat, Olga ; Xie, Yang ; Porter, Jeffery A. ; Pan, Shifeng ; Liu, Jun ; McLaughlin, Margaret E. ; Cong, FengProceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (31), p.12649-12654 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Induction of WT1 (Wilms' Tumor Gene)-Specific Cytotoxic T Lymphocytes by WT1 Peptide Vaccine and the Resultant Cancer RegressionOka, Yoshihiro ; Tsuboi, Akihiro ; Taguchi, Tetsuya ; Osaki, Tadashi ; Kyo, Taiichi ; Nakajima, Hiroko ; Elisseeva, Olga A. ; Oji, Yusuke ; Kawakami, Manabu ; Ikegame, Kazuhiro ; Hosen, Naoki ; Yoshihara, Satoshi ; Wu, Fei ; Fujiki, Fumihiro ; Murakami, Masaki ; Masuda, Tomoki ; Nishida, Sumiyuki ; Shirakata, Toshiaki ; Nakatsuka, Shin-ichi ; Sasaki, Ayako ; Udaka, Keiko ; Dohy, Hiroo ; Aozasa, Katsuyuki ; Noguchi, Shinzaburo ; Kawase, Ichiro ; Sugiyama, Haruo ; Sugimura, TakashiProceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (38), p.13885-13890 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signalingKristensen, Vessela N ; Vaske, Charles J ; Ursini-Siegel, Josie ; Van Loo, Peter ; Nordgard, Silje H ; Sachidanandam, Ravi ; Sørlie, Therese ; Wärnberg, Fredrik ; Haakensen, Vilde D ; Helland, Åslaug ; Naume, Bjørn ; Perou, Charles M ; Haussler, David ; Troyanskaya, Olga G ; Børresen-Dale, Anne-LiseProceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2802-2807 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Reactivation of Proliferin Gene Expression is Associated with Increased Angiogenesis in a Cell Culture Model of Fibrosarcoma Tumor ProgressionToft, Daniel J. ; Rosenberg, Suzanne B. ; Bergers, Gabriele ; Volpert, Olga ; Daniel I. H. LinzerProceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (23), p.13055-13059 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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The ErbB3-Binding Protein Ebp1 Suppresses Androgen Receptor-Mediated Gene Transcription and Tumorigenesis of Prostate Cancer CellsZhang, Yuexing ; Wang, Xin-Wei ; Jelovac, Danijela ; Nakanishi, Takeo ; Yu, Myoung-hee ; Akinmade, Damilola ; Goloubeva, Olga ; Ross, Douglas D. ; Brodie, Angela ; Hamburger, Anne W. ; Lardy, HenryProceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (28), p.9890-9895 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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The Human Plakoglobin Gene Localizes on Chromosome 17q21 and is Subjected to Loss of Heterozygosity in Breast and Ovarian CancersAberle, H ; Bierkamp, C ; Torchard, D ; Serova, O ; Wagner, T ; Natt, E ; Wirsching, J ; Heidkämper, C ; Montagna, M ; Lynch, H TProceedings of the National Academy of Sciences - PNAS, 1995-07, Vol.92 (14), p.6384-6388 [Periódico revisado por pares]United States: National Academy of Sciences of the United States of AmericaTexto completo disponível |
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Material Type: Artigo
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The Mechanism of Cancer-Mediated Conversion of Plasminogen to the Angiogenesis Inhibitor AngiostatinGately, Stephen ; Twardowski, Przemyslaw ; Stack, M. Sharon ; Cundiff, Deborah L. ; Grella, Davida ; Castellino, Francis J. ; Enghild, Jan ; Kwaan, Hau C. ; Lee, Francis ; Kramer, Robert A. ; Volpert, Olga ; Bouck, Noel ; Soff, Gerald A.Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (20), p.10868-10872 [Periódico revisado por pares]United States: National Academy of Sciences of the United States of AmericaTexto completo disponível |