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Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathwaysStecca, Barbara ; Mas, Christophe ; Clement, Virginie ; Zbinden, Marie ; Correa, Rafael ; Piguet, Vincent ; Beermann, Friedrich ; Ruiz i Altaba, ArielProceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (14), p.5895-5900 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic MelanomaFREDERICK, Dennie T ; PIRIS, Adriano ; WEIYI PENG ; SULLIVAN, Ryan J ; LAWRENCE, Donald P ; HODI, F. Stephen ; OVERWIJK, Willem W ; LIZEE, Gregory ; MURPHY, George F ; HWU, Patrick ; FLAHERTY, Keith T ; FISHER, David E ; COGDILL, Alexandria P ; WARGO, Jennifer A ; COOPER, Zachary A ; LEZCANO, Cecilia ; FERRONE, Cristina R ; MITRA, Devarati ; BONI, Andrea ; NEWTON, Lindsay P ; CHENGWEN LIUClinical cancer research, 2013-03, Vol.19 (5), p.1225-1231 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cellsVilgelm, Anna E ; Pawlikowski, Jeff S ; Liu, Yan ; Hawkins, Oriana E ; Davis, Tyler A ; Smith, Jessica ; Weller, Kevin P ; Horton, Linda W ; McClain, Colt M ; Ayers, Gregory D ; Turner, David C ; Essaka, David C ; Stewart, Clinton F ; Sosman, Jeffrey A ; Kelley, Mark C ; Ecsedy, Jeffrey A ; Johnston, Jeffrey N ; Richmond, AnnCancer research (Chicago, Ill.), 2015-01, Vol.75 (1), p.181-193 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Human Melanoma Metastases Demonstrate Nonstochastic Site-Specific Antigen Heterogeneity That Correlates with T-cell InfiltrationBARTLETT, Edmund K ; FETSCH, Patricia A ; KAMMULA, Udai S ; FILIE, Armando C ; ABATI, Andrea ; STEINBERG, Seth M ; WUNDERLICH, John R ; WHITE, Donald E ; STEPHENS, Daniel J ; MARINCOLA, Francesco M ; ROSENBERG, Steven AClinical cancer research, 2014-05, Vol.20 (10), p.2607-2616 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated FibroblastsANDERBERG, Charlotte ; HONG LI ; FREDRIKSSON, Linda ; ANDRAE, Johanna ; BETSHOLTZ, Christer ; XURI LI ; ERIKSSON, Ulf ; PIETRAS, KristianCancer research (Chicago, Ill.), 2009-01, Vol.69 (1), p.369-378 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Antimetastatic and antiangiogenic activity of trabectedin in cutaneous melanomaCarminati, Laura ; Pinessi, Denise ; Borsotti, Patrizia ; Minoli, Lucia ; Giavazzi, Raffaella ; D’Incalci, Maurizio ; Belotti, Dorina ; Taraboletti, GiuliaCarcinogenesis (New York), 2019-04, Vol.40 (2), p.303-312 [Periódico revisado por pares]UK: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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A spliced antigenic peptide comprising a single spliced amino acid is produced in the proteasome by reverse splicing of a longer peptide fragment followed by trimmingMichaux, Alexandre ; Larrieu, Pierre ; Stroobant, Vincent ; Fonteneau, Jean-François ; Jotereau, Francine ; Van den Eynde, Benoît J ; Moreau-Aubry, Agnès ; Vigneron, NathalieThe Journal of immunology (1950), 2014-02, Vol.192 (4), p.1962-1971 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanomaMassoumi, Ramin ; Kuphal, Silke ; Hellerbrand, Claus ; Haas, Bodo ; Wild, Peter ; Spruss, Thilo ; Pfeifer, Alexander ; Fässler, Reinhard ; Bosserhoff, Anja KThe Journal of experimental medicine, 2009-01, Vol.206 (1), p.221-232 [Periódico revisado por pares]United States: The Rockefeller University PressTexto completo disponível |
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Material Type: Artigo
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Melanoma Cells Express ICOS Ligand to Promote the Activation and Expansion of T-Regulatory CellsMARTIN-OROZCO, Natalia ; YUFENG LI ; YIJUN WANG ; SHIJUAN LIU ; HWU, Patrick ; LIU, Yong-Jun ; CHEN DONG ; RADVANYI, LaszloCancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9581-9590 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic StateYoo, Jae Hyuk ; Brady, Samuel W ; Acosta-Alvarez, Lehi ; Rogers, Aaron ; Peng, Jingfu ; Sorensen, Lise K ; Wolff, Roger K ; Mleynek, Tara ; Shin, Donghan ; Rich, Coulson P ; Kircher, David A ; Bild, Andrea ; Odelberg, Shannon J ; Li, Dean Y ; Holmen, Sheri L ; Grossmann, Allie HCancer research (Chicago, Ill.), 2019-06, Vol.79 (11), p.2892-2908 [Periódico revisado por pares]United StatesTexto completo disponível |