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1
Novel 4,5,6,7-tetrahydrobenzothiazole dopamine agonists display very low stereoselectivity in their interaction with dopamine receptors
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Artigo
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Novel 4,5,6,7-tetrahydrobenzothiazole dopamine agonists display very low stereoselectivity in their interaction with dopamine receptors

Jaen, Juan C. ; Caprathe, Bradley W. ; Wise, Lawrence D. ; Smith, Sarah J. ; Pugsley, Thomas A. ; Heffner, Thomas G. ; Meltzer, Leonard T.

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (4), p.189-192 [Periódico revisado por pares]

Elsevier Ltd

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2
RP-70676 - A POTENT SYSTEMICALLY AVAILABLE INHIBITOR OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT)
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Artigo
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RP-70676 - A POTENT SYSTEMICALLY AVAILABLE INHIBITOR OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT)

ASHTON, MJ ; BRIDGE, AW ; BUSH, RC ; DRON, DI ; HARRIS, NV ; JONES, GD ; LYTHGOE, DJ ; RIDDELL, D ; SMITH, C

Bioorganic & medicinal chemistry letters, 1992-05, Vol.2 (5), p.375-380 [Periódico revisado por pares]

OXFORD: Elsevier

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3
Anticonvulsant activity of glycine-site NMDA antagonists. 2. trans 2-carboxy-4-substituted tetrahydroquinolines
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Artigo
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Anticonvulsant activity of glycine-site NMDA antagonists. 2. trans 2-carboxy-4-substituted tetrahydroquinolines

Carling, Robert W. ; Leeson, Paul D. ; Moseley, Angela M. ; Smith, Julian D. ; Saywell, Kay ; Tricklebank, Mark D. ; Kemp, John A. ; Marshall, George R. ; Foster, Alan C. ; Grimwood, Sarah

Bioorganic & medicinal chemistry letters, 1993, Vol.3 (1), p.65-70 [Periódico revisado por pares]

Elsevier Ltd

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4
Amino acid bioisosteres: design of 2-quinolone derivatives as glycine-site N-methyl-D-aspartate receptor antagonists
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Artigo
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Amino acid bioisosteres: design of 2-quinolone derivatives as glycine-site N-methyl-D-aspartate receptor antagonists

Leeson, Paul D. ; Baker, Raymond ; Carling, Robert W. ; Kulagowski, Janusz J. ; Mawer, Ian M. ; Ridgill, Mark P. ; Rowley, Michael ; Smith, Julian D. ; Stansfield, Ian ; Stevenson, Graeme I. ; Foster, Alan C. ; Kemp, John A.

Bioorganic & medicinal chemistry letters, 1993-02, Vol.3 (2), p.299-304 [Periódico revisado por pares]

Elsevier Ltd

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5
Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties
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Artigo
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Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties

Sawyer, T.K. ; Fisher, J.F. ; Hester, J.B. ; Smith, C.W. ; Tomasselli, A.G. ; Tarpley, W.G. ; Burton, P.S. ; Hui, J.O. ; McQuade, T.J. ; Conradi, R.A. ; Bradford, V.S. ; Liu, L. ; Kinner, J.H. ; Tustin, J. ; Alexander, D.L. ; Harrison, A.W. ; Emmert, D.E. ; Staples, D.J. ; Maggiora, L.L. ; Zhang, Y.Z. ; Poorman, R.A. ; Dunna, B.M. ; Rao, C. ; Scarborough, P.E. ; Lowther, W.T. ; Craik, C. ; DeCamp, D. ; Moon, J. ; Howe, W.J. ; Heinrikson, R.L.

Bioorganic & medicinal chemistry letters, 1993-05, Vol.3 (5), p.819-824 [Periódico revisado por pares]

Elsevier Ltd

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6
Dihydropyridine KATP potassium channel openers
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Artigo
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Dihydropyridine KATP potassium channel openers

FRANK, C. A ; FORST, J. M ; GRANT, T ; HARRIS, R. J ; KAU, S. T ; LI, J. H ; OHNMACHT, C. J ; SMITH, R. W ; TRAINOR, D. A ; TRIVEDI, S

Bioorganic & medicinal chemistry letters, 1993-12, Vol.3 (12), p.2725-2726 [Periódico revisado por pares]

Oxford: Elsevier

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7
Design and synthesis of achiral 5-lipoxygenase inhibitors employing the cyclobutyl group
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Artigo
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Design and synthesis of achiral 5-lipoxygenase inhibitors employing the cyclobutyl group

Hodgson, Simon T. ; Wates, Peter J. ; Blackwell, Geoffrey J. ; Craig, Caroline ; Yeadon, Michael ; Boughton-Smith, Nigel

Bioorganic & medicinal chemistry letters, 1993-12, Vol.3 (12), p.2565-2570 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase
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Artigo
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Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase

Field, Robert A. ; Neville, David C.A. ; Smith, Roland W. ; Ferguson, Michael A.J.

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (3), p.391-394 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Synthesis and biological activity of C-5 modified derivatives of (+)-AJ76 and (+)-UH232 : increased dopamine D3 receptor preference and improved pharmacokinetic properties
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Artigo
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Synthesis and biological activity of C-5 modified derivatives of (+)-AJ76 and (+)-UH232 : increased dopamine D3 receptor preference and improved pharmacokinetic properties

HAADSMA-SVENSSON, S. R ; SMITH, M. W ; CHIU-HONG LIN ; DUNCAN, J. N ; SONESSON, C ; WIKSTRÖM, H ; WATERS, N ; CARLSSON, A ; SVENSSON, K

Bioorganic & medicinal chemistry letters, 1994-03, Vol.4 (5), p.689-694 [Periódico revisado por pares]

Oxford: Elsevier

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10
The identification of a novel renin inhibitor of equivalent efficacy following oral or intravenous administration
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Artigo
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The identification of a novel renin inhibitor of equivalent efficacy following oral or intravenous administration

Smith, S.A. ; Al-Barazanji, K.A. ; Buckingham, R.E. ; Cassidy, F. ; Coldwell, M.C. ; Finney, F.J.L. ; Hadley, M.S. ; Ham, P. ; Lawrence, S.A. ; Nash, D.J. ; Tingley, E.J.R. ; Watson, J.M.

Bioorganic & medicinal chemistry letters, 1994-06, Vol.4 (11), p.1291-1296 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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