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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Dev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen P

Nature cell biology, 2018-08, Vol.20 (8), p.954-965 [Peer Reviewed Journal]

England: Nature Publishing Group

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2
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
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Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

Eirew, Peter ; Steif, Adi ; Khattra, Jaswinder ; Ha, Gavin ; Yap, Damian ; Farahani, Hossein ; Gelmon, Karen ; Chia, Stephen ; Mar, Colin ; Wan, Adrian ; Laks, Emma ; Biele, Justina ; Shumansky, Karey ; Rosner, Jamie ; McPherson, Andrew ; Nielsen, Cydney ; Roth, Andrew J L ; Lefebvre, Calvin ; Bashashati, Ali ; de Souza, Camila ; Siu, Celia ; Aniba, Radhouane ; Brimhall, Jazmine ; Oloumi, Arusha ; Osako, Tomo ; Bruna, Alejandra ; Sandoval, Jose L ; Algara, Teresa ; Greenwood, Wendy ; Leung, Kaston ; Cheng, Hongwei ; Xue, Hui ; Wang, Yuzhuo ; Lin, Dong ; Mungall, Andrew J ; Moore, Richard ; Zhao, Yongjun ; Lorette, Julie ; Nguyen, Long ; Huntsman, David ; Eaves, Connie J ; Hansen, Carl ; Marra, Marco A ; Caldas, Carlos ; Shah, Sohrab P ; Aparicio, Samuel

Nature (London), 2015-02, Vol.518 (7539), p.422-426 [Peer Reviewed Journal]

England: Nature Publishing Group

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3
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
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A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

Polak, Paz ; Kim, Jaegil ; Braunstein, Lior Z ; Karlic, Rosa ; Haradhavala, Nicholas J ; Tiao, Grace ; Rosebrock, Daniel ; Livitz, Dimitri ; Kübler, Kirsten ; Mouw, Kent W ; Kamburov, Atanas ; Maruvka, Yosef E ; Leshchiner, Ignaty ; Lander, Eric S ; Golub, Todd R ; Zick, Aviad ; Orthwein, Alexandre ; Lawrence, Michael S ; Batra, Rajbir N ; Caldas, Carlos ; Haber, Daniel A ; Laird, Peter W ; Shen, Hui ; Ellisen, Leif W ; D'Andrea, Alan D ; Chanock, Stephen J ; Foulkes, William D ; Getz, Gad

Nature genetics, 2017-10, Vol.49 (10), p.1476-1486 [Peer Reviewed Journal]

United States: Nature Publishing Group

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4
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies
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Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

Blows, Fiona M ; Driver, Kristy E ; Schmidt, Marjanka K ; Broeks, Annegien ; van Leeuwen, Flora E ; Wesseling, Jelle ; Cheang, Maggie C ; Gelmon, Karen ; Nielsen, Torsten O ; Blomqvist, Carl ; Heikkilä, Päivi ; Heikkinen, Tuomas ; Nevanlinna, Heli ; Akslen, Lars A ; Bégin, Louis R ; Foulkes, William D ; Couch, Fergus J ; Wang, Xianshu ; Cafourek, Vicky ; Olson, Janet E ; Baglietto, Laura ; Giles, Graham G ; Severi, Gianluca ; McLean, Catriona A ; Southey, Melissa C ; Rakha, Emad ; Green, Andrew R ; Ellis, Ian O ; Sherman, Mark E ; Lissowska, Jolanta ; Anderson, William F ; Cox, Angela ; Cross, Simon S ; Reed, Malcolm W R ; Provenzano, Elena ; Dawson, Sarah-Jane ; Dunning, Alison M ; Humphreys, Manjeet ; Easton, Douglas F ; García-Closas, Montserrat ; Caldas, Carlos ; Pharoah, Paul D ; Huntsman, David Marincola, Francesco M.

PLoS medicine, 2010-05, Vol.7 (5), p.e1000279-e1000279 [Peer Reviewed Journal]

United States: Public Library of Science

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5
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

Batra, Rajbir Nath ; Lifshitz, Aviezer ; Vidakovic, Ana Tufegdzic ; Chin, Suet-Feung ; Sati-Batra, Ankita ; Sammut, Stephen-John ; Provenzano, Elena ; Ali, H Raza ; Dariush, Ali ; Bruna, Alejandra ; Murphy, Leigh ; Purushotham, Arnie ; Ellis, Ian ; Green, Andrew ; Garrett-Bakelman, Francine E ; Mason, Chris ; Melnick, Ari ; Aparicio, Samuel A J R ; Rueda, Oscar M ; Tanay, Amos ; Caldas, Carlos

Nature communications, 2021-09, Vol.12 (1), p.5406-5406, Article 5406 [Peer Reviewed Journal]

England: Nature Publishing Group

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6
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
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Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems

Alon, Shahar ; Goodwin, Daniel R ; Sinha, Anubhav ; Wassie, Asmamaw T ; Chen, Fei ; Daugharthy, Evan R ; Bando, Yosuke ; Kajita, Atsushi ; Xue, Andrew G ; Marrett, Karl ; Prior, Robert ; Cui, Yi ; Payne, Andrew C ; Yao, Chun-Chen ; Suk, Ho-Jun ; Wang, Ru ; Yu, Chih-Chieh Jay ; Tillberg, Paul ; Reginato, Paul ; Pak, Nikita ; Liu, Songlei ; Punthambaker, Sukanya ; Iyer, Eswar P R ; Kohman, Richie E ; Miller, Jeremy A ; Lein, Ed S ; Lako, Ana ; Cullen, Nicole ; Rodig, Scott ; Helvie, Karla ; Abravanel, Daniel L ; Wagle, Nikhil ; Johnson, Bruce E ; Klughammer, Johanna ; Slyper, Michal ; Waldman, Julia ; Jané-Valbuena, Judit ; Rozenblatt-Rosen, Orit ; Regev, Aviv ; Church, George M ; Marblestone, Adam H ; Boyden, Edward S

Science (American Association for the Advancement of Science), 2021-01, Vol.371 (6528) [Peer Reviewed Journal]

United States: The American Association for the Advancement of Science

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7
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting
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The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting

Severson, Tesa M ; Wolf, Denise M ; Yau, Christina ; Peeters, Justine ; Wehkam, Diederik ; Schouten, Philip C ; Chin, Suet-Feung ; Majewski, Ian J ; Michaut, Magali ; Bosma, Astrid ; Pereira, Bernard ; Bismeijer, Tycho ; Wessels, Lodewyk ; Caldas, Carlos ; Bernards, René ; Simon, Iris M ; Glas, Annuska M ; Linn, Sabine ; van 't Veer, Laura

Breast cancer research : BCR, 2017-08, Vol.19 (1), p.99-9, Article 99 [Peer Reviewed Journal]

England: BioMed Central Ltd

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8
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
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Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, Serena ; Davies, Helen ; Staaf, Johan ; Ramakrishna, Manasa ; Glodzik, Dominik ; Zou, Xueqing ; Martincorena, Inigo ; Alexandrov, Ludmil B ; Martin, Sancha ; Wedge, David C ; Van Loo, Peter ; Ju, Young Seok ; Smid, Marcel ; Brinkman, Arie B ; Morganella, Sandro ; Aure, Miriam R ; Lingjærde, Ole Christian ; Langerød, Anita ; Ringnér, Markus ; Ahn, Sung-Min ; Boyault, Sandrine ; Brock, Jane E ; Broeks, Annegien ; Butler, Adam ; Desmedt, Christine ; Dirix, Luc ; Dronov, Serge ; Fatima, Aquila ; Foekens, John A ; Gerstung, Moritz ; Hooijer, Gerrit K J ; Jang, Se Jin ; Jones, David R ; Kim, Hyung-Yong ; King, Tari A ; Krishnamurthy, Savitri ; Lee, Hee Jin ; Lee, Jeong-Yeon ; Li, Yilong ; McLaren, Stuart ; Menzies, Andrew ; Mustonen, Ville ; O'Meara, Sarah ; Pauporté, Iris ; Pivot, Xavier ; Purdie, Colin A ; Raine, Keiran ; Ramakrishnan, Kamna ; Rodríguez-González, F Germán ; Romieu, Gilles ; Sieuwerts, Anieta M ; Simpson, Peter T ; Shepherd, Rebecca ; Stebbings, Lucy ; Stefansson, Olafur A ; Teague, Jon ; Tommasi, Stefania ; Treilleux, Isabelle ; Van den Eynden, Gert G ; Vermeulen, Peter ; Vincent-Salomon, Anne ; Yates, Lucy ; Caldas, Carlos ; van't Veer, Laura ; Tutt, Andrew ; Knappskog, Stian ; Tan, Benita Kiat Tee ; Jonkers, Jos ; Borg, Åke ; Ueno, Naoto T ; Sotiriou, Christos ; Viari, Alain ; Futreal, P Andrew ; Campbell, Peter J ; Span, Paul N ; Van Laere, Steven ; Lakhani, Sunil R ; Eyfjord, Jorunn E ; Thompson, Alastair M ; Birney, Ewan ; Stunnenberg, Hendrik G ; van de Vijver, Marc J ; Martens, John W M ; Børresen-Dale, Anne-Lise ; Richardson, Andrea L ; Kong, Gu ; Thomas, Gilles ; Stratton, Michael R

Nature (London), 2016-06, Vol.534 (7605), p.47-54 [Peer Reviewed Journal]

England: Nature Publishing Group

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9
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Woo, Xing Yi ; Giordano, Jessica ; Srivastava, Anuj ; Zhao, Zi-Ming ; Lloyd, Michael W ; de Bruijn, Roebi ; Suh, Yun-Suhk ; Patidar, Rajesh ; Chen, Li ; Scherer, Sandra ; Bailey, Matthew H ; Yang, Chieh-Hsiang ; Cortes-Sanchez, Emilio ; Xi, Yuanxin ; Wang, Jing ; Wickramasinghe, Jayamanna ; Kossenkov, Andrew V ; Rebecca, Vito W ; Sun, Hua ; Mashl, R Jay ; Davies, Sherri R ; Jeon, Ryan ; Frech, Christian ; Randjelovic, Jelena ; Rosains, Jacqueline ; Galimi, Francesco ; Bertotti, Andrea ; Lafferty, Adam ; O'Farrell, Alice C ; Modave, Elodie ; Lambrechts, Diether ; Ter Brugge, Petra ; Serra, Violeta ; Marangoni, Elisabetta ; El Botty, Rania ; Kim, Hyunsoo ; Kim, Jong-Il ; Yang, Han-Kwang ; Lee, Charles ; Dean, 2nd, Dennis A ; Davis-Dusenbery, Brandi ; Evrard, Yvonne A ; Doroshow, James H ; Welm, Alana L ; Welm, Bryan E ; Lewis, Michael T ; Fang, Bingliang ; Roth, Jack A ; Meric-Bernstam, Funda ; Herlyn, Meenhard ; Davies, Michael A ; Ding, Li ; Li, Shunqiang ; Govindan, Ramaswamy ; Isella, Claudio ; Moscow, Jeffrey A ; Trusolino, Livio ; Byrne, Annette T ; Jonkers, Jos ; Bult, Carol J ; Medico, Enzo ; Chuang, Jeffrey H

Nature genetics, 2021-01, Vol.53 (1), p.86-99 [Peer Reviewed Journal]

United States: Nature Publishing Group

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10
Mutations truncating the EP300 acetylase in human cancers
Mutations truncating the EP300 acetylase in human cancers
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Mutations truncating the EP300 acetylase in human cancers

Caldas, Carlos ; Gayther, Simon A ; Batley, Sarah J ; Linger, Lori ; Bannister, Andy ; Thorpe, Karen ; Chin, Suet-Feung ; Daigo, Yataro ; Russell, Paul ; Wilson, Annie ; Sowter, Heidi M ; Delhanty, Joy D.A ; Ponder, Bruce A.J ; Kouzarides, Tony

Nature genetics, 2000-03, Vol.24 (3), p.300-303 [Peer Reviewed Journal]

London: Nature Publishing Group

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