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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Dev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen P

Nature cell biology, 2018-08, Vol.20 (8), p.954-965 [Periódico revisado por pares]

England: Nature Publishing Group

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2
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
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A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

Polak, Paz ; Kim, Jaegil ; Braunstein, Lior Z ; Karlic, Rosa ; Haradhavala, Nicholas J ; Tiao, Grace ; Rosebrock, Daniel ; Livitz, Dimitri ; Kübler, Kirsten ; Mouw, Kent W ; Kamburov, Atanas ; Maruvka, Yosef E ; Leshchiner, Ignaty ; Lander, Eric S ; Golub, Todd R ; Zick, Aviad ; Orthwein, Alexandre ; Lawrence, Michael S ; Batra, Rajbir N ; Caldas, Carlos ; Haber, Daniel A ; Laird, Peter W ; Shen, Hui ; Ellisen, Leif W ; D'Andrea, Alan D ; Chanock, Stephen J ; Foulkes, William D ; Getz, Gad

Nature genetics, 2017-10, Vol.49 (10), p.1476-1486 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

Batra, Rajbir Nath ; Lifshitz, Aviezer ; Vidakovic, Ana Tufegdzic ; Chin, Suet-Feung ; Sati-Batra, Ankita ; Sammut, Stephen-John ; Provenzano, Elena ; Ali, H Raza ; Dariush, Ali ; Bruna, Alejandra ; Murphy, Leigh ; Purushotham, Arnie ; Ellis, Ian ; Green, Andrew ; Garrett-Bakelman, Francine E ; Mason, Chris ; Melnick, Ari ; Aparicio, Samuel A J R ; Rueda, Oscar M ; Tanay, Amos ; Caldas, Carlos

Nature communications, 2021-09, Vol.12 (1), p.5406-5406, Article 5406 [Periódico revisado por pares]

England: Nature Publishing Group

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4
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting
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The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting

Severson, Tesa M ; Wolf, Denise M ; Yau, Christina ; Peeters, Justine ; Wehkam, Diederik ; Schouten, Philip C ; Chin, Suet-Feung ; Majewski, Ian J ; Michaut, Magali ; Bosma, Astrid ; Pereira, Bernard ; Bismeijer, Tycho ; Wessels, Lodewyk ; Caldas, Carlos ; Bernards, René ; Simon, Iris M ; Glas, Annuska M ; Linn, Sabine ; van 't Veer, Laura

Breast cancer research : BCR, 2017-08, Vol.19 (1), p.99-9, Article 99 [Periódico revisado por pares]

England: BioMed Central Ltd

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5
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
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Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, Serena ; Davies, Helen ; Staaf, Johan ; Ramakrishna, Manasa ; Glodzik, Dominik ; Zou, Xueqing ; Martincorena, Inigo ; Alexandrov, Ludmil B ; Martin, Sancha ; Wedge, David C ; Van Loo, Peter ; Ju, Young Seok ; Smid, Marcel ; Brinkman, Arie B ; Morganella, Sandro ; Aure, Miriam R ; Lingjærde, Ole Christian ; Langerød, Anita ; Ringnér, Markus ; Ahn, Sung-Min ; Boyault, Sandrine ; Brock, Jane E ; Broeks, Annegien ; Butler, Adam ; Desmedt, Christine ; Dirix, Luc ; Dronov, Serge ; Fatima, Aquila ; Foekens, John A ; Gerstung, Moritz ; Hooijer, Gerrit K J ; Jang, Se Jin ; Jones, David R ; Kim, Hyung-Yong ; King, Tari A ; Krishnamurthy, Savitri ; Lee, Hee Jin ; Lee, Jeong-Yeon ; Li, Yilong ; McLaren, Stuart ; Menzies, Andrew ; Mustonen, Ville ; O'Meara, Sarah ; Pauporté, Iris ; Pivot, Xavier ; Purdie, Colin A ; Raine, Keiran ; Ramakrishnan, Kamna ; Rodríguez-González, F Germán ; Romieu, Gilles ; Sieuwerts, Anieta M ; Simpson, Peter T ; Shepherd, Rebecca ; Stebbings, Lucy ; Stefansson, Olafur A ; Teague, Jon ; Tommasi, Stefania ; Treilleux, Isabelle ; Van den Eynden, Gert G ; Vermeulen, Peter ; Vincent-Salomon, Anne ; Yates, Lucy ; Caldas, Carlos ; van't Veer, Laura ; Tutt, Andrew ; Knappskog, Stian ; Tan, Benita Kiat Tee ; Jonkers, Jos ; Borg, Åke ; Ueno, Naoto T ; Sotiriou, Christos ; Viari, Alain ; Futreal, P Andrew ; Campbell, Peter J ; Span, Paul N ; Van Laere, Steven ; Lakhani, Sunil R ; Eyfjord, Jorunn E ; Thompson, Alastair M ; Birney, Ewan ; Stunnenberg, Hendrik G ; van de Vijver, Marc J ; Martens, John W M ; Børresen-Dale, Anne-Lise ; Richardson, Andrea L ; Kong, Gu ; Thomas, Gilles ; Stratton, Michael R

Nature (London), 2016-06, Vol.534 (7605), p.47-54 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Woo, Xing Yi ; Giordano, Jessica ; Srivastava, Anuj ; Zhao, Zi-Ming ; Lloyd, Michael W ; de Bruijn, Roebi ; Suh, Yun-Suhk ; Patidar, Rajesh ; Chen, Li ; Scherer, Sandra ; Bailey, Matthew H ; Yang, Chieh-Hsiang ; Cortes-Sanchez, Emilio ; Xi, Yuanxin ; Wang, Jing ; Wickramasinghe, Jayamanna ; Kossenkov, Andrew V ; Rebecca, Vito W ; Sun, Hua ; Mashl, R Jay ; Davies, Sherri R ; Jeon, Ryan ; Frech, Christian ; Randjelovic, Jelena ; Rosains, Jacqueline ; Galimi, Francesco ; Bertotti, Andrea ; Lafferty, Adam ; O'Farrell, Alice C ; Modave, Elodie ; Lambrechts, Diether ; Ter Brugge, Petra ; Serra, Violeta ; Marangoni, Elisabetta ; El Botty, Rania ; Kim, Hyunsoo ; Kim, Jong-Il ; Yang, Han-Kwang ; Lee, Charles ; Dean, 2nd, Dennis A ; Davis-Dusenbery, Brandi ; Evrard, Yvonne A ; Doroshow, James H ; Welm, Alana L ; Welm, Bryan E ; Lewis, Michael T ; Fang, Bingliang ; Roth, Jack A ; Meric-Bernstam, Funda ; Herlyn, Meenhard ; Davies, Michael A ; Ding, Li ; Li, Shunqiang ; Govindan, Ramaswamy ; Isella, Claudio ; Moscow, Jeffrey A ; Trusolino, Livio ; Byrne, Annette T ; Jonkers, Jos ; Bult, Carol J ; Medico, Enzo ; Chuang, Jeffrey H

Nature genetics, 2021-01, Vol.53 (1), p.86-99 [Periódico revisado por pares]

United States: Nature Publishing Group

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7
Signatures of mutational processes in human cancer
Signatures of mutational processes in human cancer
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Signatures of mutational processes in human cancer

Alexandrov, Ludmil B ; Nik-Zainal, Serena ; Wedge, David C ; Aparicio, Samuel A J R ; Behjati, Sam ; Biankin, Andrew V ; Bignell, Graham R ; Bolli, Niccolò ; Borg, Ake ; Børresen-Dale, Anne-Lise ; Boyault, Sandrine ; Burkhardt, Birgit ; Butler, Adam P ; Caldas, Carlos ; Davies, Helen R ; Desmedt, Christine ; Eils, Roland ; Eyfjörd, Jórunn Erla ; Foekens, John A ; Greaves, Mel ; Hosoda, Fumie ; Hutter, Barbara ; Ilicic, Tomislav ; Imbeaud, Sandrine ; Imielinski, Marcin ; Imielinsk, Marcin ; Jäger, Natalie ; Jones, David T W ; Jones, David ; Knappskog, Stian ; Kool, Marcel ; Lakhani, Sunil R ; López-Otín, Carlos ; Martin, Sancha ; Munshi, Nikhil C ; Nakamura, Hiromi ; Northcott, Paul A ; Pajic, Marina ; Papaemmanuil, Elli ; Paradiso, Angelo ; Pearson, John V ; Puente, Xose S ; Raine, Keiran ; Ramakrishna, Manasa ; Richardson, Andrea L ; Richter, Julia ; Rosenstiel, Philip ; Schlesner, Matthias ; Schumacher, Ton N ; Span, Paul N ; Teague, Jon W ; Totoki, Yasushi ; Tutt, Andrew N J ; Valdés-Mas, Rafael ; van Buuren, Marit M ; van 't Veer, Laura ; Vincent-Salomon, Anne ; Waddell, Nicola ; Yates, Lucy R ; Zucman-Rossi, Jessica ; Futreal, P Andrew ; McDermott, Ultan ; Lichter, Peter ; Meyerson, Matthew ; Grimmond, Sean M ; Siebert, Reiner ; Campo, Elías ; Shibata, Tatsuhiro ; Pfister, Stefan M ; Campbell, Peter J ; Stratton, Michael R

Nature (London), 2013-08, Vol.500 (7463), p.415-421 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Integrative analysis of array-comparative genomic hybridisation and matched gene expression profiling data reveals novel genes with prognostic significance in oesophageal adenocarcinoma
Integrative analysis of array-comparative genomic hybridisation and matched gene expression profiling data reveals novel genes with prognostic significance in oesophageal adenocarcinoma
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Integrative analysis of array-comparative genomic hybridisation and matched gene expression profiling data reveals novel genes with prognostic significance in oesophageal adenocarcinoma

Goh, X Y ; Rees, J R E ; Paterson, A L ; Chin, S F ; Marioni, J C ; Save, V ; O'Donovan, M ; Eijk, P P ; Alderson, D ; Ylstra, B ; Caldas, C ; Fitzgerald, R C

Gut, 2011-10, Vol.60 (10), p.1317-1326 [Periódico revisado por pares]

London: BMJ Publishing Group Ltd and British Society of Gastroenterology

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9
Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping
Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping
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Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

Abraham, Jean E ; Maranian, Mel J ; Spiteri, Inmaculada ; Russell, Roslin ; Ingle, Susan ; Luccarini, Craig ; Earl, Helena M ; Pharoah, Paul P D ; Dunning, Alison M ; Caldas, Carlos

BMC medical genomics, 2012-05, Vol.5 (1), p.19-19, Article 19 [Periódico revisado por pares]

England: BioMed Central Ltd

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10
TOX3 mutations in breast cancer
TOX3 mutations in breast cancer
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TOX3 mutations in breast cancer

Jones, James Owain ; Chin, Suet-Feung ; Wong-Taylor, Li-An ; Leaford, Donna ; Ponder, Bruce A J ; Caldas, Carlos ; Maia, Ana-Teresa Soares, Paula

PloS one, 2013-09, Vol.8 (9), p.e74102-e74102 [Periódico revisado por pares]

United States: Public Library of Science

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